Synephrine L-tartrate is a chemical compound formed by combining synephrine, an alkaloid naturally found in bitter oranges, with L-tartaric acid. Used in both research and manufacturing environments, this compound offers a stable, solid form of synephrine, making it easier to store and work with compared to its free base or other salt forms. From my experience in the lab, this material stands out for its consistent results and manageable properties during handling and processing. Its reputation relies on meeting rigorous standards, ensuring researchers and manufacturers receive high-purity material batch after batch.
Synephrine L-tartrate carries the molecular formula C9H13NO2·C4H6O6. The structure links a synephrine molecule—built of benzene, hydroxyl, and amine groups—to the L-tartrate ion, which is made up of tartaric acid in its L-isomeric form. This union shapes a balanced, crystalline solid. In visual terms, the lattice arrangement stays stable under standard room temperature and humidity, which is significant for those who want predictability in material handling. Detailed analysis using NMR and mass spectrometry confirms the connectivity and lends confidence during audits and quality checks.
Synephrine L-tartrate typically arrives as a white or near-white crystalline powder, sometimes resembling fine flakes or tiny solid pearls. The bulk density usually ranges from 0.5 to 0.7 g/cm³, but packing methods, storage length, and humidity can impact the result. This compound dissolves freely in water, creating a clear solution at room temperature, a benefit for formulation work. Scientists working in solution chemistry appreciate the reliable solubility, which allows for straightforward measurements without complications from cloudiness or separation. From my vantage point in a manufacturing facility, the powder’s flow and lack of stickiness mean fewer stoppages and easy transfer between containers.
Specification sheets typically list purity levels of >98% (HPLC), low moisture content <1.0%, and residue on ignition below 0.1%. Precise particle sizing supports consistent weighing and mixing, whether for laboratory protocols or scalable batch production. Synephrine L-tartrate’s Harmonized System (HS) Code often sits in the 2922.49 category, which covers other nitrogen-function compounds. In practice, procurement specialists cross-check this code against shipping documents for compliant customs clearance. Years in this field showed me that quick turnaround and delivery depend on accurate documentation, so keeping the correct HS code and certifications on the paperwork avoids logistical headaches.
Synephrine L-tartrate stays stable under standard room conditions if stored dry, away from direct sunlight and moisture. Sealed, airtight packaging preserves its low moisture content, which is important for those trying to prevent clumping or hydrolysis. Refrigeration isn’t required, saving on energy bills for companies managing larger inventories. I’ve noticed that warehouses storing organic chemicals stress the importance of secondary containment and regular inventory checks—it prevents cross-contamination, moisture intrusion, and accidental mix-ups.
Knowing what you’re working with keeps you safe. Labeling from suppliers highlights that the material can provoke mild respiratory or skin irritation if handled carelessly. No strong evidence points to significant environmental harm at typical workplace levels, but technicians wear masks and gloves anyway, just as standard operating practice. Safety Data Sheets (SDS) recommend avoiding inhalation and direct contact, and that’s something I’ve seen reinforced in good training programs—engineered controls and personal protective equipment keep risks under control. Even with a clean safety record, treating every batch as potentially hazardous ensures nobody gets complacent.
Manufacturers receive synephrine usually extracted from citrus aurantium fruits, and L-tartaric acid sourced by fermentation or chemical synthesis. The two components combine under controlled conditions, creating a high-yield reaction with minimal byproducts. Reliable supply chains mean manufacturers develop long-term relationships with growers and chemical producers, making sure batch quality and environmental factors line up with regulatory standards. I’ve found that well-managed raw material sourcing allows end users to meet GMP certification and keeps international clients happy.
Though primarily considered a chemical and raw material in industrial settings, synephrine L-tartrate pops up in everything from dietary supplement research to pharmaceutical intermediate development. Its clean, easy-to-handle format supports precise dosing and efficient blending into formulations where solubility and purity make a difference. Routine lab audits look for predictable appearance, accurate labeling, and consistent physical characteristics—qualities that draw both research organizations and industrial buyers. Having worked with both, I know material consistency can save hours, reduce rework, and build trust over time.
To prevent cross-contamination or compromised shipments, dedicated storage areas and routine container inspections stay mandatory in well-run facilities. Tamper-evident containers and precise record-keeping prevent unauthorized access and support reliable batch tracing. Improving training for warehouse staff pays off, reducing mistakes and ensuring only authorized people access chemical stores. On the procurement side, maintaining close relationships with suppliers, backed by detailed audits and compliance checks, helps companies avoid substandard raw materials—a lesson reinforced by every delayed shipment I’ve personally seen cause a ripple effect through production schedules.
| Parameter | Details |
|---|---|
| Molecular Formula | C9H13NO2·C4H6O6 |
| Physical State | White crystalline powder, flakes, or pearls |
| Density | 0.5–0.7 g/cm³ |
| Solubility | Freely soluble in water |
| Purity | Typically >98% by HPLC |
| HS Code | 2922.49 |
| Safe Handling Guidance | Use gloves, mask, and eye protection; keep storage dry and sealed |
| Hazardous Concerns | Low, but can cause mild irritation on contact or inhalation |
| Material Type | Organic salt, raw material for supplements and pharmaceuticals |
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