D-tartaric acid is generally considered safe for consumption. Regulatory agencies, including the U.S. Food and Drug Administration, have classified it as a "generally recognized as safe" substance. In Europe, it is approved as a food additive. After ingestion, most D-tartaric acid is metabolized by gastrointestinal bacteria, with approximately 15-20% excreted unchanged in the urine. Excessive intake may lead to mild side effects such as increased thirst, vomiting, diarrhea, abdominal pain, and gastrointestinal inflammation. Direct contact may cause skin or eye irritation, and inhalation of airborne particles may irritate the respiratory tract.
Although D-tartaric acid can cause muscle toxicity at extremely high doses, this is very rare and usually requires the ingestion of exceptionally large quantities. For sensitive individuals, including newborns, children, and pregnant women, it is recommended to consult a healthcare professional before taking large amounts or using it for extended periods.