This compound, with a name long enough to challenge even seasoned lab techs, falls into the category of specialty chemicals shaped for pharmaceutical research and manufacturing. Its backbone links a chloroquinoline ring, a phenyl group, and a chiral benzenepropanol moiety, each contributing function and behavior inside various applications. Years of work in chemical labs have shown me that molecules designed with such intricate architecture tend to signal high specificity, making them attractive as key actives in medicinal chemistry pathways, especially in areas aimed at targeting infections or resistant disease strains.
The presence of aromatic rings, a chloride substituent, and an alcohol group guarantees that this material does not just look interesting under a microscope. In hand, this compound commonly appears as off-white to pale yellow crystalline flakes or powder. Solid at room temperature, it boasts a density around 1.3 to 1.4 g/cm³, based on similar structures cataloged in chemical databases. Crystals isolated in pure form pass light unevenly, reflecting their high degree of order at the molecular level—a feature that usually nudges purity higher, an essential factor in regulated industries like pharmaceuticals. Dissolution occurs best in organic solvents such as ethanol, DMF, or DMSO. Water solubility stays limited, and handling fine powder will remind anyone of its need for containment and extraction systems to avoid airborne spread—a common topic in lab safety meetings.
This molecule merges several active functional groups: the quinoline ring draws from the antimalarial and antibacterial toolkit often found in drugs like chloroquine, while the para-chloro group modifies both bioactivity and metabolic stability. The ethenyl bridge links the quinoline and phenyl group, a feature adding rigidity. The benzenepropanol section carries a chiral center (S-enantiomer), impacting how this material interacts with enzymes and biological targets. The molecular formula for this compound runs roughly C27H24ClNO2, delivering a molecular weight near 430 grams per mole. Every chemist who has tried to synthesize or purify a structure with this much complexity can tell you the process demands strict control over reagents and reaction conditions. Specific melting points typically fall between 148°C and 154°C, which fits where organic intermediates of similar size and polarity land on the temperature scale.
Trade and movement of this compound fundamentally get shaped by its HS Code, commonly falling under 293349 for heterocyclic compounds with nitrogen hetero-atoms. Compliance teams file this as part of intermediate pharmaceutical ingredients or active pharmaceutical ingredients (API), sometimes splitting hairs over the exact description. Sourcing raw materials to produce this specialty item includes working with anilines, aldehydes, and quinoline skeletons—building blocks every synthetic chemist knows for their potential hazards and stringent purity needs. Raw materials often carry their own risk-laden profiles, heightening the importance of full-chain provenance tracking and supplier audits.
Industrial suppliers most commonly deliver this compound as a powder or crystalline solid, sometimes compressed as flakes to ease handling. These textures change little in reactivity, but the form chosen affects how labs measure, transport, and blend the substance into solutions. In pharma plants, dense flakes prevent static buildup, reducing contamination risk, while fine powders allow faster dissolution but require more robust dust management protocols. Liquids and pearls rarely apply to this structure unless modified into a salt or extended with solvents for solution-phase reactions. Regardless of form, everyone who has cleaned a powder spill knows the value of a good vacuum line and a quick hand with the broom.
Preparing working solutions requires careful tracking of molarity, as this compound’s weight adds up quickly. Researchers often use concentrations between 1mM to 100mM, depending on whether the goal is screening, crystallography, or bioassay development. Solutions clear up in DMSO, acetone, and, less easily, in less polar alcohols. A liter of stock solution, depending on need, stretches across projects, but storage remains a challenge—shielding from light and moisture is critical, a lesson learned after observing samples degrade to brown mush under poorly sealed caps. Gloves, goggles, and chemical fume hoods are non-negotiable, part of routine procedures in any lab with GxP compliance. It isn’t just about keeping people safe—a single slip can contaminate a batch, wrecking weeks of efforts and incurring regulatory headaches.
Government databases and material safety data sheets (MSDS) rate compounds like this for both acute and chronic health effects. Inhalation, ingestion, and skin contact each carry risk; the quinoline and chloroaromatic core in particular flag higher toxicity than simple alcohols or alkanes. Signs can include skin irritation, headaches, or more severe complications if handled without respect. Proper chemical storage means segregating from oxidizers, avoiding acid or base contact, and labeling containers with full chemical names. Facilities must equip themselves with spill kits compatible with aromatic and halogenated compounds. Disposal must follow approved hazardous waste protocols, and experienced lab staff know better than to let even a milligram slip into regular waste streams. Handling these materials brings responsibility—each gram has journeyed through costly syntheses and rigorous quality checks, and the environmental impact makes sustainable disposal and solvent recovery not just regulatory necessities but ethical imperatives for researchers and manufacturers alike.
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