(S)-(+)-2-Chlorophenylglycine Methyl Ester Tartrate: Practical Overview and Chemical Insight

What is (S)-(+)-2-Chlorophenylglycine Methyl Ester Tartrate?

(S)-(+)-2-Chlorophenylglycine methyl ester tartrate comes from a class of specialty organic compounds that find their use in pharmaceutical research and chemical synthesis. What you find is a fine or crystalline solid with a notable molecular structure: C12H15ClNO6. This molecular formula reveals its makeup and hints at its targeted roles in lab and industrial processes. A closer look at its physical state—usually appearing as white to off-white flakes or power—signals purity and suitability for precise applications. Anyone handling this chemical will notice its structure, as the chirality impacts activity, especially where enantioselectivity matters, like in drug synthesis.

Structure and Molecular Properties

Dissecting its structure, the compound merges a 2-chlorophenylglycine methyl ester with a tartrate backbone. This arrangement creates an optically active molecule, and the configuration is locked as (S)-(+), which points to its role in chiral separations or as a building block for active pharmaceutical ingredients (APIs). The specific rotation matters in synthesis—producers and chemists look for stable enantiomeric excess. Each molecule carries a chlorine atom attached to the aromatic ring, contributing both to the chemical reactivity and safety profile. From experience in labs, crystal forms often display robust lattice energies and maintain integrity during storage. Looking up density, you’ll find it ranges around 1.3–1.5 g/cm3, depending on the crystalline arrangement and purity. These values tie directly to ease of weighing and dosing in small-scale and pilot production.

Physical Form: Utility in Industry

Depending on supplier and synthesis method, (S)-(+)-2-Chlorophenylglycine methyl ester tartrate may come as solid, flakes, crystal powder, or sometimes as pearlescent grains. Practical handling depends on the finished form. Fine powders dissolve faster in common solvents, helping in rapid solution-phase reactions. Flake or crystalline forms find favor when precision dosing is critical—no dust, no loss, no unexpected reactions. In solution chemistry, it mixes well in methanol and ethanol, forming stable solutions up to reasonable concentrations. Labs working on raw material synthesis or drug intermediates value high-purity samples, and so crystalline or pearl forms—achieved through slow evaporation or careful recrystallization—are highly sought after.

HS Code, Specifications, and Applications

Customs management matters just as much as quality. The Harmonized System (HS) Code for this class typically falls within 29224995, filed under organic chemicals with specific functional groups. Anyone shipping or importing bulk quantities needs to tick all regulatory boxes: detailed specifications list melting point (often 130–140°C), specific rotational values, and purity levels above 98%. This sets it apart from less defined starting materials—pharma-grade material faces tighter checks to guarantee batch-to-batch consistency. With these specs in place, the product goes straight into research for drug discovery or as a chiral auxiliary for synthesizing active molecules with desired therapeutic traits.

Safety, Hazards, and Responsible Use

Chemicals like (S)-(+)-2-Chlorophenylglycine methyl ester tartrate demand respect. Researchers must check the latest safety data sheets and be alert to harmful outcomes: dust inhalation, skin, or eye contact can cause irritation. While the compound doesn’t rate as the most hazardous by global standards, responsible chemical stewardship holds—the use of gloves, safety goggles, and well-ventilated workspaces protects everyone, especially as powdered solids can create airborne risks. Waste disposal follows international chemical guidelines; it cannot join regular lab waste streams but needs careful incineration or treatment by licensed chemical disposers. Those overseeing chemical inventories keep detailed logs—mixing up chiral materials with achiral ones can impact research results, not to mention violate internal safety protocols.

Molecular Considerations and Future Development

Raw materials stand at the start line of innovation. Here, this ester functions as a reliable starting point for enantioselective synthesis, not just in pharma but across agrochemical and specialty chemical fields. Labs that work with this compound often push for even higher purity to reduce byproducts; process engineers fine-tune crystallization steps, shifting yields in favor of the desired enantiomer and away from unwanted isomers. Scientists track emerging purification technologies like advanced chromatography to reach the next threshold of quality. Regulatory experts, meanwhile, keep pace with shifting global standards to make sure every shipment enters the market smoothly, with full traceability from raw material to final product. For companies producing new chiral drugs or chemical building blocks, (S)-(+)-2-Chlorophenylglycine methyl ester tartrate offers a proven entry ticket into more advanced research—so understanding it from specifications to shipping code is more than a checkbox, it shapes everything that follows.