(R)-2-Methyl Piperazine (L)Tartaric Acid Salt flows from chemical synthesis labs into pharmaceutical, biotech, and specialty chemical manufacturing. Known by chemists for its unique chiral structure, this compound brings together the backbone of piperazine—a six-membered heterocyclic ring with two nitrogens—and the natural touch of tartaric acid’s chiral influence. The R enantiomer sits at the center, giving it significance for those needing absolute stereochemical control over their raw materials. Whenever strict synthesis purity or reliable enantiomeric ratios take the spotlight, this salt steps in, shaped directly from (R)-2-methyl piperazine and L-tartaric acid by carefully controlled acid-base neutralization, yielding a material valued for both its purity and consistency.
Whether handled in the warehouse or scrutinized in the lab, the solid state of (R)-2-methyl piperazine (L)tartaric acid salt reveals itself as a crystalline powder or flake. Most batches come off the production line with white or off-white color and a fine grain, sometimes resembling fine pearls under brighter light. Density hovers around 1.1–1.3 g/cm³, making it denser than many basic organic solids but still light enough for easy handling compared to denser salts or metals. Its structure combines the rigidity of the tartaric core with the flexibility of the piperazine ring, a trait appreciated when downstream solubility is key. This salt dissolves in water quickly, forms clear to slightly opalescent solutions, and remains non-volatile under standard lab conditions. Melting points often sit in the range of 170–195°C, supporting standard storage requirements without specialized thermal control. The absence of major odor, a lack of deliquescence, and resistance to casual moisture give users confidence at multiple process stops, from transfer to storage.
Chemists know that everything begins with reliable specs. The molecular formula—C11H22N2O6—captures both the complexity and the precision with which suppliers must deliver each batch. Molecular weight clocks in at 278.30 g/mol, determined by precise elemental analysis, and verified for each lot before it ever reaches downstream partners. Specifications often demand purity above 98%, with chiral purity closely monitored via HPLC or other chiral assay, as any deviation can throw off final yields in asymmetric syntheses. Water content sits low, often under 1.0%, keeping degradation at bay and ensuring that downstream reactions don’t suffer from mysterious drifts. Many applications require batch-specific specification sheets—pH in aqueous solution, heavy metal content, individual impurity profiles, and clarity of solution—to fulfill both regulatory and performance-driven needs. Each load leaves the dock bearing a customs-handled HS Code, often 2933.59, classifying it as a heterocyclic compound with nitrogen heteroatom(s) for tariff and tracking purposes.
Most users deal with this material as a fine, crystalline solid, though some processes use it in the form of flakes or small pellets. Its powder form pours easily and avoids troublesome clumping if kept dry—moisture remains the biggest enemy on plant floors. Bulk handled in lined drums or high-grade polyethylene bags, the salt resists most ambient oxidation and doesn’t generate dust hazardous to normal health, though proper personal protective equipment (PPE) should always be standard. Liquid or solution forms, usually made fresh, allow for precise dosing in pharmaceutical and peptide manufacture, but aren’t as common for shipping or distribution unless dealing directly with contract formulation labs. Each permanent container includes batch-specific labeling, up-to-date COAs (certificates of analysis), and safety guidance covering all the steps from delivery to use.
Direct experience with this salt shows that it combines mild chemical action with the necessary care of any organic raw material. Dry powder can irritate eyes, respiratory tract, and skin if handled without gloves and goggles. Ingestion or improper disposal can bring environmental risks, as solubilized piperazine derivatives sometimes possess aquatic toxicity. Most plants keep it on the shelf under non-hazardous organic solids, though standard chemical hygiene protocols apply. The Safety Data Sheet (SDS) covers splash risks, first-aid measures, fire-fighting provisions, and accidental release response, and users stick closely to recommendations for secure storage, typically at room temperature, away from acids, strong bases, and oxidizing agents. Waste management routines, as developed in pharmaceutical environments, focus on controlled neutralization and incineration, not down-the-drain disposal. Adherence to global regulatory requirements—REACH, TSCA, and GHS labeling—ensures city and state inspections pass without issue.
If you’ve ever watched a drug synthesis run rely on razor-sharp chiral purity, you’ll appreciate the importance of solid, dependable sources of (R)-2-methyl piperazine (L)tartaric acid salt. Chiral intermediates boost the successful isolation of APIs (active pharmaceutical ingredients), especially in antihistamines, antivirals, and central nervous system compounds. As a resolving agent or an intermediate, this salt helps separate racemic mixtures, ensuring the single-enantiomer outcome that modern drug standards demand. Beyond pharma, specialty chemical manufacturers pick this salt for projects that need precisely tuned reactivity, supporting industries that value fine control over reaction selectivity. Its role as a raw material doesn’t just influence yield, it swings process economics and regulatory filings, fighting for confidence in each kilogram delivered. Lot-to-lot consistency, simple handling, and detailed official certifications support development timelines and scale-up plans that run from the gram scale to multi-metric-ton campaigns.
No shop floor or development lab stays free from the bumps of sourcing, quality control, or safety management. Outsourcing to poorly vetted suppliers risks low chiral purity or unwanted contaminants. The best move is direct relationships with established chemical producers who provide full traceability, routine third-party testing, and transparent compliance records. While storage under ambient conditions works in most plants, humid climates call for extra diligence—pack everything with desiccants or vacuum-seal for long hauls or slow-moving stock. Formulators should always double-check compatibility with other excipients, as some trace components—carryover chloride, organic acids, or metal ions—can influence solubility, shelf life, or downstream synthetic reliability. Regular staff training on new handling techniques or updated protocols tightens the safety net, keeping operations clean and efficient. Waste handlers look to batch-specific SDS guidance before moving any off-spec material into the waste stream, partnering with licensed chemical disposal agents who know the ins and outs of organic salt neutralization and incineration.
From first batches in R&D up to validated production lots, (R)-2-methyl piperazine (L)tartaric acid salt stands out for reliability, precise physical properties, and versatility in a crowded raw material marketplace. Its clear specifications let manufacturers drive faster product development, secure IP positions, and lower the risk of batch-to-batch failures across growing global plants. Stored and handled right, each shipment backs up vital process steps in decades-long product lifecycles, showing why careful supplier partnerships and strict compliance matter every bit as much as physical chemistry basics. For teams building the next wave of life-changing therapies or advancing next-gen materials, this salt stands not as just another reagent, but as a cornerstone supporting scalable, reproducible, and safe innovation.
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