Noradrenaline Bitartrate Monohydrate: Physical Characteristics and Essential Properties

What is Noradrenaline Bitartrate Monohydrate?

Noradrenaline Bitartrate Monohydrate stands out in the field of pharmaceutical and chemical raw materials, known primarily for its function as an adrenergic agent and neurotransmitter. The molecular formula, C8H11NO3·C4H6O6·H2O, brings together noradrenaline with tartaric acid and water of crystallization, forming a monohydrate crystal with a specific structure. The inclusion of the monohydrate here matters because it impacts storage conditions, stability, and how the compound interacts in solution. For molecular weight calculations, its complete structure comes in around 337.3 g/mol, a figure important for lab preparations and sourcing calculations. As far as its appearance, suppliers usually provide it as a white to off-white crystalline powder, though the size and density of the flakes or crystals can differ from one batch to another. Some might see it prepared as compact pearls for controlled dosing, but most users in laboratories or manufacturing work with it as a powder for easy dissolution and precise measurement.

Physical Properties: Structure, Density, and Appearance

The structure of Noradrenaline Bitartrate Monohydrate delivers a crystalline solid with high solubility in water, which also ties directly into its applications for injectable pharmaceutical solutions. This substance does not present as a liquid under standard conditions, and its melting point hovers around 135°C, which reflects its stability during manufacturing and storage processes. The density lands at about 1.5 g/cm³. These measurements can make a difference during scale-up for pharmaceutical production or compounding. Consistency in physical form, whether as powder or larger crystals, helps with uniform distribution in solutions, and reduces the risk of dosage unevenness. In my time working alongside product development in a chemical manufacturing environment, I learned that such details often separate high-quality medical-grade material from options where purity or solubility issues can create headaches later.

Product Specifications: Safe Handling, Raw Material Insight, and Hazard Considerations

When shipped as a chemical raw material, suppliers and handlers need to focus on both safety and integrity. Noradrenaline Bitartrate Monohydrate does not usually present an extreme hazard in its solid form, though it is considered harmful upon inhalation, ingestion, or contact with skin and eyes. Its status as a pharmaceutical raw material demands careful differentiation from bulk industrial chemicals; cross-contamination or degradation from improper mixing must be avoided. The HS Code tied to this substance is 2939.41.0000, connecting it to the global catalog for import-export and regulatory compliance. Safety storage includes keeping it tightly sealed in a cool, dry environment away from direct sunlight or moisture. Simple steps such as labeling containers properly and ensuring only trained personnel have access can forestall dangerous exposure or product loss. Chemical compatibility checks remain important, since strong oxidizers or acids could compromise stability or lead to hazardous byproducts.

Uses and Solutions for Handling Noradrenaline Bitartrate Monohydrate

The demand for Noradrenaline Bitartrate Monohydrate centers on its role in pharmaceutical synthesis and emergency medicine settings. Transparent sourcing is vital: adulterated or improperly synthesized material poses risks not only to patients but also to the entire supply chain. As manufacturers look for raw material suppliers, lab certification data—such as purity tests and polymorph characterizations—offer concrete assurance against error-prone batches. In my experience, solutions for safe and reliable use often start with robust internal protocols. Each shipment must come with a certificate of analysis and test results, including checks for contaminants and identity confirmation using advanced methods like HPLC. Disposal of expired or damaged product cannot be an afterthought either. Clear procedures for chemical waste go a long way in preventing accidental environmental release or workplace accidents.

Why Knowing These Properties Matters

Overlooking minor property differences—powder versus flakes, for instance—can mean trouble for anyone trying to maintain consistent dosing or solubility in a production setting. Small gains in knowledge about structure, density, and safe handling often translate to fewer errors along the line and more predictable results for patients and practitioners. As production ramps up, keeping molecular details top-of-mind gives both technicians and decision-makers a head start on quality, safety, and compliance with international standards. Education for end users and suppliers builds reliability and allows the broader scientific and medical communities to feel confident in their chemical partners.