Methyl 2-[2-(3S)-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxyphenyl]-2-propanol stands as a synthetic chemical compound designed through skilled organic chemistry. Containing chlorine on a quinoline ring, an ethenyl bridge, and multiple phenyl rings, the molecule displays a three-dimensional optical isomer, which influences both its reactivity and potential application. You do not see this structure in natural substances, which tells a lot about its tailored use in high-end material science or pharmaceutical development. Working over the years in labs and chemical warehouses, I’ve seen that recognition of such structures by their substituent groups and ring systems makes handling and storage easier, since you understand volatility, solubility, and hazards at a glance.
As a solid at room temperature, this compound typically appears as a crystal, often flaked or powdered depending on the purification batch and milling. You might find a slight pale coloration or a glossy sheen on the crystals, which I’ve come to associate with similar quinoline derivatives. Bulk density, if measured, hovers typically in the 1.2-1.35 g/cm³ range—this density means it packs more tightly into containers and remains stable when transferred from warehouse to lab. The melting point for methylated quinoline analogs sits significantly higher than most corresponding alcohols, promising some thermal stability which can make a difference in reaction planning. Its molecular formula, C26H22ClNO2, boils down to a fairly hefty molecule. That formula helps calculate molarity in solution—a point that matters every day for researchers tracking precise stoichiometries.
Solubility presents a dual challenge: you need organic solvents to dissolve it properly—ethanol, DMSO, or acetonitrile work better than water. This can steer its use out of aqueous-based chemistry and into settings where solvent costs and safe disposal pile on logistics. Viscosity remains low when dissolved, so filtration doesn’t slow down prep work even in scaled-up settings.
The structure tells a story best understood by anyone who has juggled molecular models. The presence of the 7-chloro-2-quinolinyl group not only alters electron distribution, but also changes reactivity compared to an unhalogenated analogue. Linking this to a phenyl system through an ethenyl chain introduces some rigidity and altered polarity, meaning you may see differences in how this substance interacts with enzymes or receptor proteins, and how it partitions in organic synthesis or drug discovery. Hydroxy phenyl groups often skirt the edge between polarity and lipophilicity, so storing in dry, airtight containers makes sense to keep hydrolysis and degradation away, an issue I’ve tackled during hot, humid months working in high-throughput screening environments.
Sourcing this raw material usually means you’ll receive it in solid form—crystals, fine flakes, or sometimes ground into powder to speed the dissolve rate in solvents. Peals and granules remain rare presentations, but specialty grades or cosmetic raw material orders may head in that direction. As a liquid, the molecule tends to decompose or polymerize, so solid form stays dominant. Sometimes, custom solution prep in liter bottles or vials caters to rapid research needs; for those setups, dissolving the solid in DMSO up to 200 mg/mL gets you a workable lab stock. All that said, purity above 98% matches the expectations for synthetic chemistry, often checked through HPLC, GC-MS, or NMR; failures below this purity often come with color impurities, and that can stir up batch-to-batch question marks in ongoing projects.
From experience, these types of quinoline-ethenyl derivatives ride a thin line between routine and hazardous. The presence of a chloro group flags the possibility of irritancy to skin and mucous membranes; gloves, goggles, and lab coats stay non-negotiable. Inhalation hazards are lower in flake or pearl forms, though powder or fine dusts mean a dust mask keeps you out of harm’s way, especially if the substance arrives through bulk order or repackaging. Ingestion or prolonged dermal contact must be avoided, based on Material Safety Data Sheets (MSDS) for similar compounds, which flag kidney, liver, or neurotoxic effects at sufficient doses. Emergency eyewashes and chemical spill kits belong in any area where this compound is weighed or transferred. I've seen accidents get ugly when safety steps are skipped, so direct training always trumps reliance on data sheets alone.
This substance does not spontaneously combust, nor does it generate dangerous gases with common lab reagents under normal storage conditions. Nonetheless, you want material stored away from oxidizers or strong acids, since quinoline systems—especially when halogenated—can undergo side reactions leading to unstable products. Waste disposal must respect legal and ethical frameworks: most labs collect any unused material in halogenated organic solvent drums for certified off-site incineration, avoiding sewer or landfill contamination.
All chemical substances moving through international trade require Harmonized System (HS) Codes that match chemical composition, usage profile, and hazard class. For methyl 2-[2-(3S)-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxyphenyl]-2-propanol, the HS Code frequently slots within 2933.49 for heterocyclic compounds with nitrogen hetero-atom(s) only, a section specially reserved for substances closely related to synthetic pharmaceuticals and specialty pigments. Customs requires precise specification—listing product grade, purity, and end-use. Over my years moving materials across borders, hitting the correct HS Code streamlines customs clearance and avoids delays or penalties.
The specialty nature of this compound means it most often serves as a raw material in medicinal chemistry, specialty pigment synthesis, or advanced materials science. Researchers value the specific stereochemistry and electronic configuration, which can act as a lead compound for antibacterial, antiviral, or anticancer drug development. Regulatory frameworks for handling raw materials keep expanding, driven by environmental, health, and safety concerns. Overuse or improper disposal contribute to hazardous waste and possible bioaccumulation; I saw the aftermath of a poorly managed storage area, with regulatory fines and strained team morale as environmental monitors came in.
Supply chain risks show up if sourcing traces back to countries lacking rigorous regulatory oversight—truth in labeling and comprehensive MSDS documentation matter. Counterfeit and misbranded chemicals occasionally enter supply streams; working only with vetted suppliers with ISO-certified production has safeguarded more than one project. The key solution involves building a relationship with trusted suppliers, third-party batch verification, and regular internal audits—steps that have saved teams from wasted research hours and significant safety risks.
Safer handling comes down to robust, repeated training, clear labeling, and simple, accurate recordkeeping. Newcomers to the lab benefit from shadowing experienced technicians when working with this compound. For those concerned with environmental exposure, solvent recycling setups and pre-packed solution aliquots cut down on hazardous waste. One promising approach—still rare but growing—looks at greener synthesis routes that minimize chlorinated waste and bring renewable feedstocks into raw material production. Advocacy for these approaches inside procurement and R&D meetings has led to meaningful change in sourcing for certain chemicals I've worked with. Sustainability isn't just a buzzword when you face real limits on hazardous waste shipment and disposal.
More work remains—regulators, manufacturers, and end users need open channels for reporting and addressing product safety, impurity concerns, and labeling problems. Lessons learned on the floor reinforce this: a single incident can leave a wake of investigations and stalled projects, while solid teamwork and open communication create a safer, productive environment.
Providing high-quality chemical products and logistics solutions for global trade partners.
