Metaraminol Hydrogen (+)-Tartrate: Properties, Structure, and Safe Handling

What is Metaraminol Hydrogen (+)-Tartrate?

Metaraminol hydrogen (+)-tartrate features strongly in pharmaceutical circles and chemical supply chains. As a derivative of metaraminol, this compound works as a powerful vasopressor. The main use: helping to manage low blood pressure episodes in clinical environments. Structurally, it includes the tartrate salt form of metaraminol, which improves its solubility and stability when dissolved. Its significance continues to rise in medical practice, particularly for patients in critical care needing sustained blood pressure support. The pharmaceutical sector depends on reliable sources and consistently pure forms to ensure therapeutic predictability and patient safety.

Physical Properties

This compound typically appears as a crystalline solid. On close inspection, you notice colorless to off-white crystals or powder. Density lands near 1.4 g/cm³, and the melting point hovers around 162°C. It dissolves readily in water, making it manageable in liquid pharmaceutical preparations without residual particulate matter. Flakes, pearls, or powder form may result from the manufacturing process or particular storage environments, but all these forms perform identically in documented laboratory and medical uses. Given its water solubility, clinicians and pharmacists can depend on it for accurate dosing solutions without the need for advanced mixing techniques, helping practitioners deliver exactly what patients need.

Chemical Structure and Formula

Scientific literature recognizes the molecular formula as C9H13NO2·C4H6O6. This combines the metaraminol core with the tartaric acid counterion, forming a salt that brings out desirable characteristics—most notably, increased chemical stability. Chemists can confirm the integrity of this structure with standard analytical techniques such as infrared spectroscopy and NMR, which show expected peaks and shifts unique to this salt formation. Trust in reproducible batch-to-batch quality connects directly to thorough analysis, making manufacturing transparency essential in supporting public health and clinical reliability.

Specifications and HS Code

Suppliers and regulatory agencies list metaraminol hydrogen (+)-tartrate under HS Code 2934999099, a designation used for import, export, and tracking in international trade of organic pharmaceutical preparations. Product specifications demand a high level of purity, usually above 98%, verified by HPLC or similar methods. Each batch arrives accompanied by a certificate of analysis, giving peace of mind to pharmacists, clinicians, and regulatory bodies alike. Precise measurements of loss on drying, residue on ignition, and identification through chemical reaction further validate each shipment.

Product Forms: Solid, Powder, Flakes, Pearls, Liquid, and Crystal

End-users find this compound in several physical forms. Crystalline flakes or pearls are common, but so is powdered form. Each brings practical advantages in storage, weighing, and processing. Hospitals and compounding pharmacies prefer powdered and crystalline versions for easy reconstitution, while research labs sometimes ask for solutions to streamline assay development. Consistency across forms reduces risk in handling for staff already navigating strict medical or lab procedures. On-site conversion of solid to solution remains straightforward due to high solubility, eliminating worries about unpredictable concentrations.

Material Safety, Hazardous Properties, and Safe Handling

Metaraminol hydrogen (+)-tartrate falls under substances that demand respect in a professional environment. Direct skin or eye contact produces irritation, and inhalation of dust ought to be avoided. Safe handling protocols involve gloves, goggles, and dust masks, especially when transferring or weighing powder. Spills require immediate cleanup with inert absorbent material. Occupational settings address these needs with clear signage, accessible first aid, and rigorous training. Safety data sheets detail the toxicological risks: ingestion or improper use leads to hypertension, headache, or other cardiovascular responses, so professional vigilance remains non-negotiable. Storage requirements call for cool, dry, well-ventilated spaces, away from incompatible chemical raw materials that trigger unwanted reactions.

Raw Materials Sourcing and Chemical Industry Role

The quality of metaraminol hydrogen (+)-tartrate depends on the caliber of raw materials and controlled synthesis methods. Suppliers prioritize pharmaceutical-grade tartaric acid and metaraminol, maintaining strict batch traceability and in-process controls. Each stakeholder plays a part: from bulk chemical manufacturers to logistics networks, every link in the chain impacts both safety and final product quality. Responsible sourcing matches regulatory compliance and gives downstream users the resources to meet patient care standards. The chemical supply industry adapts constantly to new regulations and demand fluctuations, but the foundational principle stays the same—transparent operations and robust quality assurance define what end-users receive.

Addressing Hazards and Improving Safety

Chemical safety goes beyond protocols written on paper. Facility managers invest in regular hazard drills, updated personal protective equipment, and safety audits to catch potential oversights. For metaraminol hydrogen (+)-tartrate, the risk profile stays low if handled with respect and kept away from incompatible substances or uncontrolled conditions. Greater digitalization in tracking and monitoring inventory adds a valuable layer of security and transparency, especially important where high-purity chemical raw materials serve the most at-risk populations: patients in intensive care.

Supporting Public Health and Scientific Integrity

The use of metaraminol hydrogen (+)-tartrate ripples out through health care and research. Clinical outcomes rely on unbroken trust in the supply chain, and that depends on every stakeholder understanding both the properties and potential risks of the compound. From synthesis to bedside, transparent specifications, honest communication, and strict standards give nurses and doctors the confidence to use this vasopressor without hesitation. Strong documentation trails and willingness to adapt processes according to new information or best practices offer real-world solutions for safeguarding patient well-being and scientific progress.