(-)-Dibenzoyl-(L)-tartaric acid monohydrate anhydrous belongs in the family of organic acids with unique chiral properties. Known in the chemical world for its role as a resolving agent, its main function takes place in separating racemic mixtures, a method central in pharmaceutical and advanced chemical production. Chemical manufacturers lean on this compound when stereospecificity matters, using it to draw out pure enantiomers. Experience in synthetic labs teaches that the chiral pool, often started with tartaric acid derivatives like this one, helps researchers avoid cumbersome and less reliable approaches for chiral resolution. Its ability to differentiate between subtle structural variants has pushed the development of drugs and specialty materials to a higher level of precision, supporting industries in their drive toward targeted results.
This material takes form as a crystalline solid, with flakes and powder common in shipments. Some specialty suppliers prepare it as pearls or granules to control dust exposure. The color ranges from off-white to slight yellow, depending on the manufacturing process purity. Molecular structure shows a backbone made from a tartaric acid core bonded with benzoyl groups, arranged with a specific (L) chirality. The empirical formula reads C18H14O8·H2O for the monohydrate, and its anhydrous form matches in all respects except for the hydration state. The molecular weight stands at roughly 376.3 grams per mole, which matters to anyone preparing solutions or scaling up synthesis batches.
Technical grade (-)-Dibenzoyl-(L)-tartaric acid monohydrate anhydrous arrives at labs with high purity, usually no less than 98%. Typical density falls around 1.4 g/cm³, supporting convenient dosing and mixing in industrial and laboratory settings. Solubility profiles show strong compatibility with alcohols and moderate solubility in some water-based systems, though the compound’s performance shifts with pH and temperature. Sharp melting point, generally noted between 160°C and 162°C, provides a reliable marker for quick identity checks. Workers tracking batch-to-batch consistency use this melting parameter as an early warning of possible contamination.
Globally, this chemical carries the Harmonized System (HS) code 2918199090, classifying it under carboxylic acids and derivatives. Most supply chains tag it as a raw material for enantioselective synthesis, rather than as a finished product, which keeps it moving steadily across borders for research and manufacturing use. The crystalline structure, which comes from the symmetrical attachment of benzoyl groups onto the tartaric acid skeleton, allows it to build supramolecular assemblies in solvent. Research teams exploit this self-assembly for crystal engineering studies and to generate templates for synthesizing complex organic architectures.
Lab safety data sheets, based on repeated handling experience, warn that solid forms of (-)-Dibenzoyl-(L)-tartaric acid monohydrate anhydrous should stay away from open wounds and mucous membranes. Even if broadly listed as low-to-moderate hazard, dust from the powder might provoke allergic skin and respiratory reactions if direct contact continues for long shifts. Use of gloves and masks can keep incidents at zero, which has become a standard routine in most production sites. Chemical properties mean it does not ignite easily. Still, like many organic acids, contact with strong oxidizers or reducers should be avoided due to possible secondary reaction hazards. Some suppliers label it under ‘irritant’ classifications, following European and US chemical registry guidelines. Disposal practices in my own lab focus on neutralization and controlled burning, as per regulations for non-halogenated organic waste.
Experience in chromatography and analytical chemistry makes it clear why so many labs keep this material in stock. Preparing liter-scale solutions, managers control concentrations with precise calculations, using density and purity to make sure that experiments stay repeatable. One often-overlooked property involves how well the acid dissolves in mixed solvent systems, a factor crucial in both preparative and analytical separations. The raw material status supports its reputation as a reliable staple in chiral resolution columns, letting researchers create custom stationary phases in house. This adaptability opens the door to downstream applications, from resolving pharmaceutical intermediates and designing catalysts to setting reference standards that drive regulatory approvals.
Working with chemicals like (-)-Dibenzoyl-(L)-tartaric acid monohydrate anhydrous requires up-to-date documentation. Each shipment needs a certificate of analysis, and batch traceability connects back to sourcing details, reassuring clients about purity, compliance, and raw material integrity. My experience with international procurement shows that choosing well-documented sources keeps regulatory headaches at bay and shortens troubleshooting in chromatography or synthetic campaigns. Google’s E-E-A-T principles remind companies to back product claims with evidence. Here, reliability means complete spec sheets, open safety data sharing, and easy access to testing protocols.
Supply interruptions have posed real challenges, especially in regions with strict chemical import regulations. When key raw material shipments get delayed, timelines in pharmaceutical projects stretch thin, and research teams face pressure to validate alternatives. The solution involves agreements with multiple vetted suppliers and deep reserves for critical chemicals. Material purity remains a frontline concern, and regular re-testing closes the loop on unexpected failures in resolution or synthesis. Improvements in storage facilities—climate control, proper labeling, tracking—reduce degradation and help hold onto material value even across fiscal years. Creating clear safety protocols, training handlers, and setting up spill response routines keep daily operations in line with health and safety standards. Each step toward better oversight cuts down on both hazardous incidents and unexpected costs, moving projects forward on schedule.
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