Di-p-Toluoyl-D-Tartaric Acid Monohydrate remains a specialty chemical recognized for its optically active properties, serving roles in chiral resolution and analytical chemistry. Structurally, the compound consists of two p-toluoyl groups attached to a D-tartaric acid backbone, along with one molecule of crystallization water. This raw material appears either as a white or off-white solid, typically in flaky, powder, or crystalline form. Sometimes, larger manufacturing batches yield compact pearls, making handling and measuring straightforward. Its solid form transitions neither to liquid nor easy solution at room temperature, although solubility increases in alcohols and certain organic solvents. Chemists frequently reference the molecular formula C20H20O9•H2O, with a molecular weight of 408.39 g/mol.
The molecular configuration features four carboxyl groups, two p-toluoyl aromatic rings, and asymmetric carbon centers that grant it chiral purity. These aspects ensure high specificity in enantioselective synthesis and facilitate the separation of racemic mixtures. Density hovers around 1.4 g/cm³ at 20°C, which feels very typical for solid organic acids in laboratory contexts. It usually comes as translucent to white crystalline flakes or powder, never as a liquid under normal storage. The crystalline form makes it visually easy to distinguish from less pure materials, helping anyone running a laboratory to quickly verify the quality of their supply. Water of crystallization supports the lattice structure without making the compound any less manageable in everyday use.
Chemical suppliers highlight purity above 98% for chiral applications, sometimes guaranteeing optical rotation values above 105°, measured in ethanol at 20°C. Flakes and powder tend to dominate distributions, reducing physical waste and making dissolution in suitable media more efficient. Materials received in pearl form break cleanly with moderate force, without splintering dust, which cuts down exposure risks and waste. Chemically, this compound falls under HS Code 2918.19, covering carboxylic acids and derivatives, with a global reach in industry compliance. Specific surface area and bulk density specifications generally reflect the supplier’s milling process, yet end-users mostly value easy dispersion in laboratory-scale quantities.
Users can’t ignore safety information. Di-p-Toluoyl-D-Tartaric Acid Monohydrate warrants precautions similar to other aromatic acids. It can irritate eyes, mucous membranes, or skin upon direct contact, especially in powder form, even though it’s less volatile. Always wear gloves, eye protection, and a dust mask or respirator during handling and transfer. Storage recommendations remain consistent: dry conditions, room temperature, and sealed containers to prevent clumping or absorption of atmospheric moisture. Spilled flakes or powder should be swept up promptly and disposed of with chemically compatible waste, never simply washing it down the drain.
The use of Di-p-Toluoyl-D-Tartaric Acid Monohydrate centers on separation science, often as a resolving agent for chiral bases and amines in pharmaceuticals or advanced material synthesis. Modern demands push for reduced wastage and greener disposal, so many labs adopt micro-scale testing and shift toward closed-system dispensers to cut down on airborne particles. Some organizations review source raw materials to favor batch traceability, ensuring less risk of contamination and easier compliance audits. Researchers lean on standardized solutions in ethanol or methanol at set concentrations, which lowers exposure and increases accuracy. Consistent labeling and adherence to local chemical hazard protocols make sure personnel feel supported by a culture of safety, not just written rules.
At its core, the molecule reflects thoughtful design, featuring p-toluoyl rings positioned for maximal performance in asymmetric synthesis. Suppliers source raw materials like D-tartaric acid, carefully selecting botanical or biotechnological origins to meet strict traceability goals. Chemical reactions introduce p-toluoyl chloride, with byproducts removed systematically to support high-purity outcomes. End-users depend on the compound’s predictable melting point (between 131°C and 134°C) and low volatility, giving flexibility across research and scale-up operations. Density, crystalline stability, and ease of weighing lend themselves well to specifications critical for pharmaceutical and analytical chemistry projects.
Consistent availability and price stability shape procurement decisions for research, pharma, or chemical supply chains. Environmental responsibility grows more relevant, especially where sizable quantities reach waste streams. That means stricter documentation, improved batch packaging, and ongoing attention to new green disposal regulations. Workers at every stage—from chemical operators to principal investigators—value reliable product descriptions, technical support, and hands-on training. The industry gradually drives cycle improvements: minimizing hazardous waste, expanding recoverable solvent options, and supporting broader hazardous materials education. All these steps combine to keep Di-p-Toluoyl-D-Tartaric Acid Monohydrate not just useful, but aligned with broader safety and sustainability goals.
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