(+)-Di-p-toluoyl-D-tartaric acid (Anhydrous) steps into the discussion as a chiral resolving agent, widely valued across chemical and pharmaceutical circles. Its systematic name sums up a mouthful, but the character and utility stick out in research labs and industrial settings. Its molecular formula, C20H18O8, drops a hint at its structure: two p-toluoyl groups attached to D-tartaric acid, making a compound designed to separate mirror-image molecules. This quality holds huge importance in the synthesis of drugs and advanced materials where only one enantiomer gets the job done or passes regulatory hurdles.
The physical form of this compound straddles solid territory. People often spot it as white to off-white crystalline flakes or powder. Touching it feels gritty. Sometimes, you come across pearls or dense granules, but flakes and powdered samples dominate the shelves. It carries no distinct smell, but airborne dust can tickle the nose or throat—a gentle reminder to work with a mask and gloves. Density hovers around 1.36 g/cm3. Its melting point, about 180°C, serves as a guidepost for handling and processing. The molecule’s backbone, complete with four oxygen atoms poised for hydrogen bonding, builds intermolecular strength—think stability in storage, less risk of clumping, steady shelf life.
Chemists recognize (+)-Di-p-toluoyl-D-tartaric acid (Anhydrous) not just by its molecular formula, but by its CAS number: 32634-66-5, and by the HS Code 2918199090 in customs paperwork. Every specification sheet brings up its high assay values, usually no lower than 98.0% purity. Heavy metal content sinks as low as possible, often under 10 ppm. Infrared and NMR analysis lines up with its structure; specific optical rotation sits in the range expected from D-tartaric backbones branched with p-toluoyl groups. Not all batches flow like water, but proper particle size keeps weighing and mixing straightforward, especially when working up calibration standards in analytical labs.
This material rarely shows up in liquid form. Production lines and research benches bust open bottles with solid, crystalline product. Whether you scoop out fluffy flakes or coarse, slightly glossy powder, the substance blends well in solution or suspensions. Dissolving (+)-Di-p-toluoyl-D-tartaric acid in ethanol, methanol, or water produces clear to faintly hazy solutions, depending on concentration and temperature—something to check before committing to reaction setups. Delivered in sealed drums, bottles, or polyethylene-lined containers, every shipment must steer clear of moisture. Any slip can turn the compound sticky or clumpy, never a good sign in an analytical workflow.
There’s a practical side to safety here. (+)-Di-p-toluoyl-D-tartaric acid (Anhydrous) doesn’t explode, support combustion, or bring immediate environmental drama. At the same time, nobody should treat it as harmless—like many tartaric derivatives, it can cause eye and skin irritation. Breathing in fine dust creates risk, particularly in tightly sealed production spaces. Safety Data Sheets recommend gloves, goggles, dust masks, and proper ventilation, since chronic exposure, even at low levels, hasn’t been mapped out in fine detail. Avoid combining it with strong bases or oxidizers. Rushed, careless mixing creates chemical waste and headaches. Following regular disposal channels keeps everyone on the right side of hazardous chemical legislation.
(+)-Di-p-toluoyl-D-tartaric acid (Anhydrous) transforms chiral drug synthesis. Companies focused on antihistamines, beta-blockers, and antidepressant manufacturing use it to purify and resolve mixtures into single enantiomers—one always works better, triggers fewer side effects, and achieves better regulatory outcomes. Chemical engineers use bulk shipments to drive kilo-scale separations; academic groups pour grams at a time in glass columns, aiming for the cleanest analytical splits. Its dependable solubility and high melting point streamline recovery and reuse after extraction, giving budget-conscious labs a break on raw material costs. As regulations keep steering production toward pure, well-characterized molecules, sourcing quality (+)-Di-p-toluoyl-D-tartaric acid (Anhydrous) makes the difference between a successful process and a regulatory rerun.
Raw material supply comes from refined tartaric acid and carefully controlled toluoylation reactions. Producers with established environmental monitoring push for green production routes, cut down on solvent waste, and recycle mother liquors. End-users focus not just on chemical purity, but traceability, batch-to-batch consistency, and verified non-contamination from genetically modified organisms or regulated allergens—a response to growing demands in the pharmaceutical and nutritional supplement sectors. Some vendors offer smaller-scale, premium-grade product for cutting-edge chiral research. Others drive prices down with bulk container shipments, targeting the industrial manufacturer with an eye on every dollar spent.
The line between safe handling and risky shortcuts runs through the heart of chiral separating agents. Teams stay alert, track new safety data, and push for automation wherever possible to keep workers away from dust and skin contact. Laboratories training new chemists teach proper weighing, handling, and disposal from the start. No system shields everyone from spills, but regular training and good equipment go a long way. Chemical suppliers tweak materials to control dust, improve resuspension, and shrink packaging waste. Tighter controls over contaminant metals and solvent residues raise the bar for pharmaceutical-grade supply—meeting a standard that supports public health as well as day-to-day safe chemistry.
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