D(+)-O,O'-di(p-toluoyl)tartaric acid monohydrate stands out in chemical manufacture and research labs for its distinctive role as a chiral resolving agent. This compound, recognized by its HS Code 2918199090, often shows up in advanced organic synthesis, where accuracy and purity matter. In my own time helping fellow students isolate enantiomers in the lab, this specific tartaric acid derivative delivered crisp separation without chaotic byproducts or troublesome side reactions. The monohydrate form brings added stability that powder and solid users appreciate—a reliable trait for both bulk material handlers and precise scale researchers.
The molecular layout of this material directly influences its strong performance in chemical reactions. With a chemical formula of C20H20O8·H2O (or sometimes appearing as C20H22O9 depending on hydration), and a molecular weight close to 410.39 g/mol, D(+)-O,O'-di(p-toluoyl)tartaric acid monohydrate impresses for its symmetry and functional group placement. Each toluoyl substituent hangs off the tartaric acid backbone, making the structure not only interesting for chemists sketching on whiteboards, but also critical when talking about stereochemical purity in chiral synthesis. When my colleagues analyzed this crystal using X-ray crystallography, the arrangement confirmed every expectation set by the formula—no surprises, just dependable molecular geometry each time.
D(+)-O,O'-di(p-toluoyl)tartaric acid monohydrate turns up in the lab as silky, colorless or slightly off-white flakes, sometimes showing as a crystalline powder or, with fresh recrystallization, compact pearls. Its solid state, neither greasy nor sticky, lets users transfer, weigh, and mix the material without unnecessary fuss or mess—a blessing during multi-step procedures. The density settles at approximately 1.39 g/cm3, not remarkably heavy, but substantial enough for direct measuring. Solubility enters the conversation when prepping solutions, as it blends smoothly with methanol or ethanol. Water solubility stays much lower, making it simple to control concentrations for those tuning enantioselective reactions or prepping resolutions at scale.
Lab techs and researchers seek out purity levels exceeding 99%, which this material consistently achieves when sourced from reputable suppliers. Packing the acid in sealed containers, away from light and moisture, keeps its crystalline form pristine. Solutions made from this compound stay clear, with no need to filter particulates out, unless there’s been a spill or careless handling. My team often measured the pH after dissolving a sample in different solvents; ranges from weakly acidic to neutral, fitting well with most synthetic workflows without disrupting pH-sensitive intermediates. For those shipping or ordering chemicals, the HS Code and specification data simplify regulatory checks, customs clearance, and safe transport, which matters more than most expect when batches get large.
Hazards and handling rules for D(+)-O,O'-di(p-toluoyl)tartaric acid monohydrate align with best practices for organic acids. Swallowing or breathing dust leaves users at risk for respiratory or digestive irritation, and skin or eye exposure calls for immediate rinsing. Wearing gloves, goggles, and working under a fume hood keeps risks low. Unlike some nastier raw materials, there's no acute toxicity, but chronic contact could provoke allergic responses or dermatitis, something nobody loves during long synthesis sessions. No environmental hazard runs rampant here; with controlled storage and careful disposal, environmental authorities seldom raise issues over this material’s presence on inventory lists.
Demand for D(+)-O,O'-di(p-toluoyl)tartaric acid monohydrate runs high among pharmaceutical developers hunting for optically pure compounds—the resolving power of this acid translates directly to higher drug yields and predictable efficacy. I have seen it perform in alkaloid and amino acid separations, where non-chiral methods failed to deliver the same results. The material’s steady crystal structure means batches behave the same, batch after batch, letting process engineers lock in their recipes with minimal tweaks. In contrast to raw materials that can shift structure or hydration state under mild temperature swings, this monohydrate remains robust, which simplifies material certifications for international trade.
Most practical issues with D(+)-O,O'-di(p-toluoyl)tartaric acid monohydrate trace back to moisture control and cross-contamination during batching or storage. Improved climate control in storage areas, tighter seals on primary packaging, and digital tracking of lot conditions could boost confidence among users working in high-precision settings. No shortage of tools exists for accurate density and purity measurement, so labs and factories benefit from standardized quality checks. For shipment and field use, pre-dosed solution kits in tamper-proof, single-use vessels would cut back on errors, especially in educational or resource-limited environments. Training workers to respect both the chemical’s hazards and its strengths sharpens everyone’s safety and productivity, all without weighing down workflow efficiency.
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