Creatine Gluconate combines two key components: creatine and gluconic acid. This produces a molecular structure with improved water solubility compared to regular creatine monohydrate. Its chemical formula, C10H19N3O8, and molecular weight of 325.27 g/mol set it apart from other forms of creatine on the market. The creatine base remains a favorite for athletes and bodybuilders, but many opt for the gluconate derivative to experience smoother mixing in water and fewer digestive complaints. This hybrid offers potential advantages for those who struggle with the grainier texture or bloating that sometimes comes with classic creatine forms.
Creatine Gluconate comes as a white to off-white solid, typically produced in fine powder, flakes, or crystalline pearl forms. The solid dissolves easily in water, resulting in a clear, colorless solution that is virtually odorless and slightly sweet. Unlike some chemicals that lump together or form clumps in high humidity, Creatine Gluconate’s stability impresses both manufacturers and users. At ambient temperatures, it typically retains a specific density in the range of 1.45 to 1.50 g/cm3. It has a notable melting point above 120°C, where it begins to decompose, so handling high heat isn’t recommended. Bulk densities may vary depending on granulometry but hover between 0.5 to 0.8 g/ml in powder form. Many companies offer it as a raw material, shipped in multi-layered bags to protect against moisture pickup.
Structurally, each Creatine Gluconate molecule features the well-known creatine backbone linked to a gluconic acid group through a glycosidic bond. This makes the molecule both more hydrophilic and less prone to forming insoluble aggregates. Manufacturers measure purity through HPLC or titrimetric assays, targeting a minimum creatine content of 60%. Loss on drying values usually stay under 8%, affirming low residual moisture. Standard specifications also limit heavy metals below 20 ppm and guarantee absence of harmful impurities. Particle size remains a frequent consideration, where most applications benefit from a D90 value less than 300 microns. Institutions like the FDA recognize it as a food-grade additive, provided firms adhere to strict GMP norms during production and packaging.
The Harmonized System (HS) Code for Creatine Gluconate usually falls under 2925.20.90 for customs classification. For companies importing or exporting this substance, knowing this code helps with tariff calculations and ensures compliance in documentation for customs clearance. Since regulatory agencies focus on traceability and transparency in dietary ingredients, confirming the correct HS Code reduces setbacks at borders. Some countries may require additional safety or purity certificates before products enter food or supplement supply chains.
A lot of performance nutrition products now rely on Creatine Gluconate because it dissolves so efficiently. In powders, the fine particles mix quickly into liquids; athletes rarely complain about sediment in the bottom of their glass. Premixed drinks can maintain a clear appearance, even after days on the shelf. Beyond sports nutrition, researchers look at it as a delivery form for clinical use, especially in hospitals for patients with muscle loss or wasting. Its compatibility with sweeteners, flavors, and other supplements broadens how it’s used, all while retaining stability across a variety of temperatures and pH levels. Companies also sell Creatine Gluconate in solid tablet, pearl, and capsule forms for ease of swallowing.
Safe handling matters, especially with any chemical raw material. Creatine Gluconate falls under the category of non-hazardous material for general handling and shipping when proper procedures are followed. Most users only need gloves and a simple dust mask to prevent mild irritation from air-dispersed powder. The substance is not listed as acutely toxic on government databases, and published studies show low risk of harmful effects at nutritional doses. Manufacturers still keep it clear: store Creatine Gluconate in cool, dry spaces in tightly sealed containers to protect against moisture uptake and clumping. Spilled powder isn’t flammable, nor does it emit harmful fumes under ordinary conditions, but spills should be swept up without generating excess dust.
Despite the safety record, over-consumption brings some risk, as with any dietary ingredient. Exceeding recommended dosages might stress kidneys in people with underlying problems. Some have reported mild digestive upset if taken on an empty stomach, though this effect remains less common than with creatine monohydrate. For the chemically sensitive, it’s better to choose reputable brands with third-party purity testing, since lower-grade imports could contain contaminants. MSDS resources classify Creatine Gluconate as not hazardous for aquatic life and not a corrosive solid, so large-scale accidental spills pose little risk to soil or waterways under normal conditions. Personal experience storing and handling this material for supplement manufacture has shown that with sensible storage habits, the product remains stable and safe well past its published shelf life.
Sourcing Creatine Gluconate sometimes presents hurdles, since global supply chains for gluconic acid and creatine depend on chemical plants that may suffer from disruptions. Manufacturers should diversify suppliers to keep consistency high and costs manageable. Counterfeit powders with lower purity or adulterants sometimes enter commercial supply, so investing in rigorous in-house quality testing pays off in the long run. Clear labelling builds trust among consumers; publishing batch-specific purity and heavy metal levels helps customers make informed choices. Adding QR codes for certificates of analysis on product packages lets end-users verify what they receive. If brands educate consumers about proper use and scientifically supported dosages, they cut the risk of side effects and boost customer satisfaction. As Creatine Gluconate becomes more popular, the supplement industry stands to benefit from building stronger partnerships with regulators, ramping up education among professionals, and enhancing transparency from raw material sourcing all the way to finished products.
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