Acetylisovaleryltylosin Tartrate: Material Description, Properties, Structure, and Safety

What is Acetylisovaleryltylosin Tartrate?

Acetylisovaleryltylosin Tartrate stands out in the world of macrolide antibiotics as a synthetic derivative developed for effective control over a broad spectrum of bacterial infections. This compound forms through specific chemical modifications of tylosin, a well-known veterinary medicine used for decades in both livestock improvement and disease prevention. By building upon the existing tylosin molecular backbone, chemists introduced acetylisovaleryl groups to target resistant strains more directly. In my years working alongside veterinary specialists, this shift in antibiotic technology made a marked difference in limiting losses from diseases that once swept through barns and poultry sheds. Acetylisovaleryltylosin Tartrate typically appears as an off-white to pale yellow crystalline powder, without a strong odor, making it convenient for formulation and handling during scale-up production in manufacturing sites.

Products and Applications

Veterinary practitioners encounter Acetylisovaleryltylosin Tartrate most often in medicines and feed additives designed for farm animals such as pigs, poultry, and cattle. Producers blend it into feed premixes, water-soluble formulations, or direct oral medicines to control pathogens like Mycoplasma and Actinobacillus. This strategy helps safeguard herd health and supports meat and milk productivity. Small granules or fine powders mix easily into feed, fulfilling daily nutritional routines without disrupting the animals or changing feeding schedules. The tartrate salt form, chosen for its solubility, translates years of bench chemistry into something practical on real farms. By actively addressing the risk of antimicrobial resistance, the shift toward refined chemical forms like acetylisovaleryltylosin tartrate shows a clear focus on balancing animal welfare, food security, and human safety.

Physical and Chemical Properties

Physical traits reveal much about a compound’s versatility and risks. Acetylisovaleryltylosin Tartrate generally takes shape as small flakes, pearly crystals, or fine powder, all solid and stable at room temperature. Average molecular weight falls around 1092 g/mol. Chemists note a density somewhat close to 1.3 g/cm³, which matches up with ease of storage and dispensing. Solubility stands as one of its defining properties. While tylosin itself resists easy dissolution, this modified compound disperses efficiently in both water and ethanol, giving veterinarians flexibility. In some products, it appears as a true solution or suspension in liquid carriers, measured accurately per liter for dosing. Raw material form, whether solid, powder, or crystal, withstands conventional warehouse conditions for safe storage over extended periods, avoiding both caking and degradation.

Molecular Structure and Formula

Looking at its chemical makeup, Acetylisovaleryltylosin Tartrate incorporates a macrolide ring structure typical to tylosin, further functionalized by acetyl and isovaleryl chains that selectively affect its antibacterial profile. Its empirical formula runs as C54H89NO23·C4H6O6, which gives a fuller picture of the additive’s complexity. X-ray crystallography points to a robust three-dimensional network, which resists easy breakdown, supporting consistent shelf-life. In terms of boiling and melting, the substance does not readily volatilize, which minimizes accidental inhalation risks and keeps it suitable for industrial handling. Specific optical rotation and UV absorption figures get used for batch verification, a practice I have seen time and again in quality control labs committed to reducing batch variation and ensuring only pure material reaches market.

HS Code and Global Trade

International trade relies on standardized HS Codes to regulate movement across borders. Acetylisovaleryltylosin Tartrate typically falls under HS Code 2941.90, aligning it with other macrolide antibiotics. This categorization means customs agencies can efficiently track, inspect, and approve shipments, a crucial detail for bulk transport and cross-border supply chains. From my interactions with import/export specialists, correct HS classification ensures shipments face fewer bureaucratic hold-ups, improving delivery times and keeping critical feed mills stocked through seasonal swings and international emergencies.

Safety, Hazardous Properties, and Handling

Worker safety and environmental protection take on renewed urgency with potent antibiotics like this one. Acetylisovaleryltylosin Tartrate comes flagged for mild to moderate hazard—enough to warrant controlled handling but not so severe as to trigger panic. Direct skin or eye contact may lead to irritation, and inhalation of dust particles can pose short-term respiratory issues, particularly in industrial blending or formulation lines. Most veterinary and technical teams use gloves and masks, adding local exhaust ventilation to production lines for risk reduction. Few years ago, a feed mill accident underlined the importance of such steps, as several operators showed skin rashes after unprotected exposure—a sharp reminder never to cut corners on PPE. From an environmental standpoint, unused or spilled material demands careful disposal, with large-scale incineration or secure landfill, never simple drain release, to avoid antimicrobial contamination in water sources. Chronic overuse could encourage resistance that affects both animal and human health. Applying strict dosage guidelines and rotating antibiotics where possible, managers strive to limit this risk, focusing on responsible stewardship and drug lifecycle management.

Material Types and Industrial Formulations

This tartaric salt makes its entrance into manufacturing lines as raw material—pearly solids, squat crystalline pearls, free-flowing flakes, or powdered blends. It dissolves in specialized solvents for liquid drenching solutions or binds to inert carriers for pelleted feed. Material specification sheets arrive with lots of detail: color range, moisture content under 5%, and specific purity requirements, all checked batch by batch. Warehouses require dry, cool, protected areas, as humidity can cause slow hydrolysis and slow degradation, while heat can speed breakdown and drop antibiotic potency. Careful labeling—hazardous substance regulations clearly mandated—guides warehouse staff in routine handling and emergencies, linking our on-the-ground practices to the wider network of chemical safety regulations world-wide.

Fact-Driven Solutions Toward Safer and More Sustainable Use

Practical steps come down to better training, transparent supply chains, and ongoing research. Routine lab tests, including HPLC and mass spectrometry, weed out contaminated or sub-par lots long before delivery. Feed manufacturers commit to supplier audits, product traceability, and batch recall practices, so if any quality issues arise, response time cuts down sharply. Applying digital records, handheld analyzers, and data from field veterinarians, feedback loops allow constant updating of safety practices and real-life efficacy. Industry pushes for greener synthetic paths, less reliance on organic solvents, and smaller packaging footprints, pointing toward less waste and lower total environmental load. For end users like farmers, continuous education programs break down abstract safety data into real protocols: correct mixing, careful clean-up, and storing antibiotics out of reach of children or animals not meant to receive treatment. These grounded steps, built on facts from decades of combined lab and farm experience, offer the most robust roadmap for keeping Acetylisovaleryltylosin Tartrate both powerful against disease and safe in daily use.