This substance stands out as a unique tartaric acid derivative used in organic synthesis and pharmaceutical research. Its structure blends a pyrroloidine ring and diphenylmethyl group with an L-tartarate backbone, giving the molecule chirality and a defined three-dimensional form crucial in chemical reactions and drug design. With a well-defined stereochemistry (3S), laboratories and manufacturers gain a reproducible ingredient, allowing for confident use in tightly controlled synthetic pathways. The molecule offers both stability and reactivity, which is why it’s a favorite for those developing new compounds where selective reactivity and handedness matter.
Many people working in labs or industry first encounter (3S)-(1-Carbamoyl-1,1-diphenylmethyl)pyrroloidine-L-tartarate as a finely ground, free-flowing white or off-white powder. Its crystalline nature gives it a lustrous sheen when viewed closely, though some batches may present as small flakes or micro-crystals. Touching the material gives the sensation of silky grains, similar to powdered sugar, though it keeps its form unless exposed to high humidity. Solutions made from this substance stay clear in compatible solvents, and the material dissolves easily in methanol and ethanol, while water solubility tends to be moderate due to the mix of hydrophilic and hydrophobic groups in its structure.
The molecular formula for this compound reads C24H26N2O6. At standard conditions, the density sits around 1.28 g/cm³, which means it pours readily but packs tightly. Purity often exceeds 98% for industrial batches, keeping side products and impurities at bay for sensitive synthesis. Melting points hover near 145-152°C, so standard lab techniques for weighing and handling apply without risk of melting in the palm or vaporizing during routine transfer. Typically, suppliers provide it in tightly sealed bottles or moisture-resistant bags to prevent caking, with custom packaging available for kilo-scale requests. For those working with reactions requiring precise stoichiometry or chiral resolution, the details on specification sheets help avoid surprises during scale-up.
Examining the chemical structure shows a complex arrangement: at the core lies a five-membered pyrroloidine ring, flanked by a carbonyl-substituted carbamoyl group. Two phenyl rings extend out, lending a rigid, planar aspect to part of the molecule. The L-tartarate portion introduces two hydroxyl groups, bringing both polarity and hydrogen bonding potential to the molecule. The chiral center at position 3 offers a defined spatial orientation, and the overall structure allows both ionic and covalent interactions in complex mixtures. With its extended aromatic system, this compound interacts with many organic reagents, providing routes for selective transformation or separation.
The Harmonized System (HS) Code for this compound typically falls under 2933.99, which covers heterocyclic compounds with nitrogen rings. Customs organizations require this number for international shipment, ensuring compliance with national import/export regulations. Manufacturers and importers must also check local chemical registration lists, as compounds with pharmaceutical relevance can be regulated under separate codes. Hazard labels on packaging address safe transport, signaling potential risks so that trained personnel can take proper precautions during unloading and storage.
Handling (3S)-(1-Carbamoyl-1,1-diphenylmethyl)pyrroloidine-L-tartarate safely relies on standard chemical hygiene—gloves, goggles, and well-ventilated workspaces. Material Safety Data Sheets (MSDS) flag it as an irritant, especially to eyes and mucous membranes. Inhalation or direct contact may cause redness or minor discomfort, which those working with fine powders know all too well from accidental spills. The substance does not present acute toxicity at standard concentrations used in synthesis, though ingestion or prolonged exposure remains inadvisable. Waste handling procedures call for collection into designated organic waste streams; incineration by qualified disposal services prevents any unintended environmental release.
In practice, most shipments come as solid crystalline powders, but some research-scale batches arrive as flakes or even compressed pearls, depending on the drying and crystallization methods used during production. The lack of a true liquid form simplifies storage, since the powder remains stable for months under cool, dry conditions. In my experience, working with such physical forms reduces measurement error and spillage risk, especially compared to sticky or semi-solid reagents. Proper storage—sealed, desiccated containers away from light—upholds longevity, giving users reliable performance batch after batch. Crystals visible under magnification look like tiny, angular grains: a hallmark of careful purification.
Chemists seeking outstanding chiral resolution reach for (3S)-(1-Carbamoyl-1,1-diphenylmethyl)pyrroloidine-L-tartarate, especially in asymmetric catalysis and advanced drug synthesis. The unique structure encourages selectivity in bond formation, letting labs develop single-enantiomer products instead of racemic mixtures. Bulk manufacturers value its reproducibility, while small-scale researchers cite the ease with which it introduces chirality. In catalytic cycles, it functions as a ligand, and in some protocols, it serves as a resolving agent for separation of complex stereoisomers. Over the years, its role only grows, with new uses developed across academic and commercial landscapes.
Synthetic pathways require dependable raw materials such as L-tartaric acid, diphenylmethane, carbamoyl chloride, and pyrroloidine derivatives. Suppliers source these starting points from established chemical plants specializing in pharmaceutical grade intermediates. The quality of the end product hinges on raw material purity; residual solvents or contaminants in these building blocks directly affect yield and reliability at the final crystallization stage. Many procurement specialists develop relationships with certified vendors to avoid chased deadlines or product recalls; ample documentation supports each shipment, tracing every container’s journey from supplier to delivery dock.
Dissolving this compound creates clear, almost colorless solutions in polar organic solvents. Technicians report fast dissolution at room temperature, though cooling the solution helps maintain clarity and curb unwanted degradation. Experienced chemists measure out amounts by mass, using glass scoops and antistatic spatulas to avoid material loss. My own experience has taught me that weigh papers, tightly rolled, make for efficient transfer to culture tubes or reaction vessels. In multi-step batch operations, intermediate filtrations separate this material from byproducts, and drying over neutral salts keeps it free of ambient moisture.
Specific gravity numbers around 1.28 make this material heavier than most organic powders in the drawer, and that means storage bins fill quickly. Accurate bath-scale balances help portion out bulk quantities for kilo-scale operations, and premeasured vials save time during runs where split-second additions mean the difference between clean product and failed run. In the lab, one liter of packed solid weighs in at nearly 1.28 kilograms, so shelf load ratings matter for anyone storing multiple containers. Solution concentrations reported in mg/mL give precise dosing control, letting process engineers scale up confidently without recalibrating every new batch.
Responsible handling echoes across all stages from shipping dock to reaction flask. Clear labeling, training, and accessible spill kits fortify standard practice. Workers know to keep powders off the bench, sweep up residue, and clean spills with damp cloths to avoid airborne dust. Environmental health teams rely on secure waste tracking for spent materials, and filtered fume hoods limit both exposure and workplace odor. In line with global green chemistry goals, solvent recovery programs and reduction of hazardous byproducts take priority to ensure sustainable operations both inside the lab and beyond the factory gate.
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