3-(S)-(+)-(1-Carbamoyl-1,1-diphenylmethyl)pyrroloidine-L-(+)-tartarate stands out in the world of specialized chemicals due to its complex molecular backbone. Lab workers and chemical manufacturers recognize it as more than just a chemical name; it carries real weight in pharmaceutical synthesis and research. Many professionals turn to it for its chirality and the role it plays in developing enantiomerically pure compounds. The product emerges in various forms, meeting research goals in powder, crystalline, or even slightly flaked states. Each batch brings visible stability, clear off-white shading, and a touchable texture that resists caking, which makes handling manageable. As a shipping material, it demands airtight packaging because atmospheric moisture agitates its consistency. Laboratories often spot this compound in glass vials, sometimes in bulk jars for larger formulation runs. Denser than typical laboratory reagents, this compound adds a noticable heft, especially compared to related raw materials.
Anyone familiar with specialty chemicals learns to respect clear property boundaries, and 3-(S)-(+)-(1-Carbamoyl-1,1-diphenylmethyl)pyrroloidine-L-(+)-tartarate defines its own space. Chemically, the formula C24H26N2O6 stands out right away — a solid backbone dressed with classic diphenylmethyl and pyrroloidine structures. The molecular weight clocks in around 438.48 g/mol, heavy enough for precise formulation but not so large as to limit dissolution options. In the lab, this substance gives off a clean vibe: crystalline structure catches the light, and in the powder form it pours steadily, avoiding the notoriously messy static cling encountered with other organics. Its density comes in at about 1.2 g/cm³, meaning it sits between standard pharmaceutical excipients and lighter, less complex reagents. It shows no glaring volatility, so you won’t see it evaporate or fume at standard temperatures. Most solutions of this compound prefer neutral-to-slightly-basic pH levels. It fits in comfortably among research chemicals not because it breaks records, but because it stands up to rigorous purification and analysis.
This molecule looks complicated on paper — and under a chemist’s hand lens, the connections between the pyrroloidine ring, diphenyl groups, and the tartarate’s snug fit tell a story about stability and reactivity. The stereochemistry delivers specific outcomes in reactions where orientation and arrangement matter more than mere presence. Knowing its structure translates to knowing how it will act as a chiral auxiliary or intermediate, and lab teams don’t cut corners measuring and tracking it. Its specification sheets trace purity past 99%, showing the consistency that industries crave. NMR, IR, and HPLC fingerprinting all re-confirm the identity every time — a reminder of trust built through repeated, consistent results. One wrong angle in its structure and downstream pharmaceutical reactions would lose their bite. Storage environment matters, too — temperature under 25°C and tight seals, not just for shelf life but also to retain the physical integrity that researchers and synthetic planners count on. Each detail lays out the expectation that quality gets built from starting material up, never left to chance.
Trading this compound across borders or buying it in bulk places it squarely under the global microscope. The World Customs Organization has it tagged under HS Code 2933, which covers heterocyclic compounds with nitrogen hetero-atom(s), setting off regulatory alarms for export, import, and specific end-uses. Administrators in charge of customs paperwork run regular checks on certificate authentication, not just for intellectual property reasons but also to make sure hazardous goods don’t go where they shouldn’t. Country-specific rules fold in: reach into the EU and importers reference REACH dossiers and CLP labeling; send it to the USA, and the EPA or DEA may check up on precursor status, depending on the declared use. Manufactures and distributors keep COAs (Certificates of Analysis) on record just as much for compliance as for reassuring their buyers.
Chemists and technicians working hands-on see the variation: some lots pour in thick, almost fluffy powders, while others arrive as coarse flakes or large, irregular granules. In a vial, it can settle in wide crystal sheets, thick enough you can hear them break with a glass rod. Handling differences depend on the supplier and storage practice — fresher batches resist caking and bridge between granules, but exposure means larger crystals pull moisture and clump. Its presenting form affects weighing’s accuracy, and it changes how quickly it dissolves in solvents, so process techs tend to grind and homogenize before scaling up reactions. Rarely found in liquid or pearl forms, labs prefer the stable crystalline state for both manual and automated addition into reaction vessels.
One thing anyone handling large jars of this compound notices: it packs firmly and settles if stored long. Its bulk density near 1.2 g/cm³ means a half-liter jar carries real weight, useful when batch scaling but demanding sturdy shelving. In suspension, it dissolves best in polar organic solvents; ethanol, methanol, and acetone all draw out its molecules efficiently, while water gives mixed results unless heated or strongly stirred. Most techs quickly move to solution-phase work, knowing undissolved clumps mean wasted material and inconsistent reaction profiles. For those running pilot plants or large kilo-lab units, reliability in behavior allows optimized mix times and solvent use, trimming waste and cost. The powder’s flow character rates average: not prone to explosion risk from static or quick pour, but sensitive enough to require dry scooping conditions and anti-moisture labeling.
Every safe handling protocol for this tartarate centers on precaution. Toolkits for weighing and mixing keep dust exposure down, with teams using gloves and masks to offset minor inhalation or skin sensitivity risks. The compound’s profile shows low acute toxicity, but its full safety data pulls from studies of raw material classes — meaning teams don’t take shortcuts or rely on assumptions from close analogues. Disposal protocols follow chemical regulations: never into the drain, always through lab waste streams segregated for organic hazardous materials. In the event of fire, standard dry chemical extinguishers suffice, but good practice keeps it away from open flames and strong oxidizers. For workers in less formal setups or without full PPE coverage, an extra layer of caution helps avoid eye or throat irritation from accidental exposure. Material Safety Data Sheets stress its safe but cautious handling, pointing to gaps in broader toxicological data and the need for ongoing assessment, especially if new long-term uses or higher production volumes start trending.
Chemical manufacturers searching for reliable chiral auxiliaries put a premium on this tartarate’s structure. The rigid links across the diphenyl and pyrroloidine units lock in the desired configuration, giving synthetic chemists predictable paths through multi-step syntheses. As a starting material, its clear chirality makes it a cornerstone in the production of single-enantiomer pharmaceuticals, while in specialty synthesis its molecular resilience opens up options for further elaboration. The presence of amide, ester, and tartarate groups makes it amenable to a range of transformation steps, cementing its place in the synthetic playbook. Each kilogram delivered to a plant means a new batch of intermediates—direct links from laboratory theory straight to drug development pipelines, where precise starting materials spell the difference between breakthrough and wasted time.
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