3-(S)-(1-carbamoyl-1,1-diphenylmethyl)pyrrolidine tartrate, known by chemists for its stable structure and unique stereochemistry, belongs to a category of complex organic compounds that stand out in specialty synthesis. The backbone of this material, the pyrrolidine ring, joins with a 1-carbamoyl-1,1-diphenylmethyl group, bringing in bulk, rigidity, and reactivity. This configuration helps researchers explore advanced pharmaceutical intermediates, agrochemical building blocks, or even specialty catalysis. In daily use, most labs interact with the tartrate salt form for its increased solubility and ease of manipulation. Scientists often focus on the pure (S)-enantiomer, favoring predictable chiral reactions and clean processing lines.
The formula for this compound, C20H22N2O5 (molecular weight around 370.4 g/mol), reflects a dense structure rich in functional groups. Each molecule holds both amide and carboxylate functionalities, as well as twin phenyl rings that help stabilize it during reactions. High-performance liquid chromatography usually confirms the stereochemical purity, which matters for medical or regulatory acceptance. The tartrate counter-ion—derived from tartaric acid—adds extra layers of hydrogen bonding, making crystallization and solid-state storage more reliable. Seen under standard microscopes, pure batches appear as fine crystalline flakes or white powder, sometimes forming dense pearls or, if moisture sneaks in, compact lumps.
This compound makes itself known in the lab by its texture and density. Typically, fresh samples turn out as bright white, crystalline solid, or sometimes off-white flakes depending on drying methods or particle size. When measured, the density lands near 1.28 g/cm³ among solid samples at 20°C; this information helps when measuring reagents or making stock solutions. Its melting point often sits around 98–102°C, though sample purity, particle size, and atmospheric humidity can shift this by a few degrees. Most chemists dissolve it in polar organic solvents—methanol, ethanol, DMSO—enabling clean mixing and filtration. As a non-hygroscopic solid under sealed conditions, it keeps well, but poor storage brings on caking and minor discoloration. Large operations sometimes move the solid into solution (often between 20–50% w/v in organics), allowing for precision dosing and ease in automated delivery.
Making 3-(S)-(1-carbamoyl-1,1-diphenylmethyl)pyrrolidine tartrate demands robust controls at every step. Raw materials run from substituted diphenylacetonitrile, carefully protected pyrrolidine intermediates, and crystalline tartaric acid. Each precursor gets screened for minor contamination since stereochemical drift or byproduct formation affects downstream applications. Industrial setups stress tight filtration, rigorous monitoring of stereochemistry, and batch-specific documentation. High purity, usually greater than 99% for pharmaceutical or research use, underpins regulatory and end-user confidence. Product gets packed in tightly-sealed bottles or lined drums, labeled with net weight, batch number, and synthesis date, along with safety sheets for all handlers.
Import and export rules for 3-(S)-(1-carbamoyl-1,1-diphenylmethyl)pyrrolidine tartrate follow international customs standards. The applicable Harmonized System (HS) Code, subject to confirmation by local authorities, most often belongs to organic chemicals or pharmaceutical intermediates—2905, 2922, or close variants depending on jurisdiction. The precise assignment considers functional groups, exact molecular structure, and end application. Manufacturers and traders stay vigilant, as misclassification can gum up shipments and create legal headaches. Certificates of Analysis, Material Safety Data Sheets, and country-of-origin documentation travel with every lot, streamlining clearance at ports and border inspections.
Working with 3-(S)-(1-carbamoyl-1,1-diphenylmethyl)pyrrolidine tartrate means respecting both its chemical and health hazards. The compound, while stable under normal conditions, may act as an irritant to skin or eyes if touched or splashed. Inhalation of fine powder dust during weighing or mixing triggers mild but persistent respiratory irritation. Safety training in most research labs includes proper PPE—nitrile gloves, safety goggles, and dust masks during transfer. Spills need thorough cleanup with appropriate absorbents; fine powders drift far on a stray breeze. Material safety data and international chemical safety regulations (such as GHS) mark it as potentially harmful if ingested, although acute toxicity remains low barring reckless exposure. Disposal routes align with standard treatment for non-halogenated organic materials—combustion in industrial incinerators or careful dilution and chemical neutralization, keeping groundwater and ecosystems safe. Waste minimization and closed systems usually cut down workplace exposure and environmental risk.
In real-world labs and industrial plants, 3-(S)-(1-carbamoyl-1,1-diphenylmethyl)pyrrolidine tartrate shows up inside development projects for experimental drug candidates, chiral ligands, enzyme mimics, or next-generation pesticides. Synthesis specialists rely on its reliable chiral configuration to unlock new forms of selectivity during catalytic hydrogenation or asymmetric addition reactions. The compound’s chemical backbone holds up under tough processing steps, resisting racemization at moderate temperatures and staying intact in most polar solvents. Its use as a raw material or intermediate climbs when teams hunt for patent-protected compounds that shrug off generic competitors. In academic and start-up settings, students and young chemists run hands-on explorations of reactivity, learning how stereochemistry transforms molecular behavior. Safe packaging, clear documentation, and tracked storage keep day-to-day risks in line, supporting a responsible research culture.
The global demand for this compound reflects the growing push towards precision medicines and green chemistry. International suppliers build capacity to keep up with orders from high-tech pharmaceutical companies, specialty chemical outfits, and academic programs. Careful selection of transport partners minimises exposure to crushing or moisture during long hauls, especially for sensitive crystalline forms. Vendors maintain clear supply chain traceability, reporting batch origins and stepwise synthesis data right down to solvent lots and drying times. Recent years have seen custom synthesis options for alternative salt forms or D-isomers, but the (S)-tartrate draws the widest range of buyers. As regulatory burdens rise worldwide, the best producers invest in product stewardship, hazard communication, and transparent pricing—giving research and production chemists fewer logistical headaches and more room to innovate.
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