This chemical compound belongs to the family of substituted phenoxypropanolamines and takes the form of its hydrochloride salt for common laboratory and industrial handling. The compound incorporates a dimethylamino group, a propanol backbone, an ether linkage, and a methoxy-substituted phenylethyl moiety, reflecting a complex structure that promises specificity in action and behavior. Laboratories and industry value this category of drug intermediates and research materials for their unique properties, making them essential in further synthesis or as reference standards.
The molecular structure balances an aromatic ring system with both hydrophilic and hydrophobic segments, leading to interesting solubility and interaction behaviors. The methoxy group at the 3-position of the phenyl ring increases lipophilicity, affecting both the transport across membranes and the crystal formation upon conversion to the hydrochloride. The hydrochloride group centers stability, converting the otherwise oily or viscous free base into a manageable, stable solid form. The empirical formula, typically represented as C21H28ClNO3, puts its molecular weight at approximately 377.9 g/mol. With such a structure, researchers handle the compound with care not just for its pharmacological interest but also for its material science applications.
2-Propanol, 1-(dimethylamino)-3-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]-, hydrochloride appears in several forms depending on environmental conditions and preparation methods. Most labs and suppliers work with it as a fine powder or crystalline solid, usually white or nearly white. The substance sometimes forms larger flakes, rarely granules or pearls, with a density close to 1.08 g/cm³—about typical for organic hydrochlorides. Melting points typically range from 155°C to 165°C, with high purity samples trending towards the upper limit. Solubility comes out moderate-to-high in water and alcohol, less so in nonpolar solvents, reflecting the polar nature conferred by both the ammonium chloride and methoxy group. Material compatibility demands storage in dry, cool places to suppress hydrolysis or degradation, while keeping the compound free from strong acids, bases, and oxidizing agents. The physical state—solid, powder, flake, or crystalline—determines its handling, mixing, and suitability for scaling in production or research.
Analytical labs and chemical manufacturers enforce tight specifications on material purity, usually up to ≥98%, with strict impurity profiles to avoid any interference in downstream applications. The packaging frequently employs airtight, light-resistant bottles or drums, holding quantities from a few grams for R&D up to kilogram scales for production. Whether people encounter the compound as raw material or a formulated solution, accurate content determination—by techniques like HPLC or NMR—remains routine, securing batch-to-batch reproducibility and regulatory compliance.
Customs and international trade require an accurate classification, and this compound fits within the HS Code 2922.19.00, covering oxygenated amino compounds and derivatives. Classification affects import-export duties and regulatory reporting, both critical for moving such materials between research institutes, manufacturing partners, and drug development facilities. Getting the right HS Code affects not just paperwork but risk management, insurance, and traceability systems across national borders.
People working with 2-Propanol, 1-(dimethylamino)-3-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]-, hydrochloride should take standard laboratory precautions. The hydrochloride exerts a mild-to-moderate irritation to eyes, skin, and respiratory tract on contact, translating into the need for gloves, goggles, and good local ventilation. Technical data sheets and SDSs describe it as harmful on ingestion and possibly hazardous on prolonged exposure, though low volatility reduces the risk of inhalation in most environments. Avoid direct ingestion, inhalation, and skin contact. In case of spills, prompt cleanup with minimal dust generation best preserves personal safety. Waste must go as hazardous chemical material, not routine trash.
The compound serves as an intermediate for more complex drug molecules, or as a reference material across the pharmaceutical industry, especially where β-adrenergic receptor ligands or related molecules are required. Raw materials entering production include dimethylamine, 2-propanol, and bespoke substituted phenol derivatives, with hydrochloric acid entering at the final synthetic step for salt formation. Its specific roles vary, but synthesis, storage, and shipment rely heavily on physical characteristics discussed above to guarantee reproducibility and safety. Those in medicinal chemistry keep close eyes on purity, form, and storage to prevent loss of activity or unexpected reactions. Whether in the form of a liter of solution or a bag of pure powder, the chemical stands at the crossroads of research, regulation, and practical application, always underlining the value of safe, precise handling and quality assurance.
Providing high-quality chemical products and logistics solutions for global trade partners.
