2-(Benzyloxy)-3-propanediol belongs to a class of organic compounds that features both a benzyloxy group and a propanediol backbone, giving it a unique blend of chemical and physical properties. This material appears as a solid under standard conditions, transitioning to a powder or crystalline form with slight temperature changes. In laboratory work and industry, it pops up as a raw material for various syntheses, demonstrating utility across specialties such as pharmaceuticals, chemical manufacturing, and advanced materials research. The molecular structure supports its function in various reaction pathways, making it a reliable choice when chemists look for a building block that offers both reactivity and selectivity.
People working in chemical synthesis value 2-(benzyloxy)-3-propanediol for its performance during specialty reactions. It acts as a precursor in the development of certain pharmaceutical intermediates and specialty polymers. In my own experience at the research bench, the material allowed clean transformations when a benzylic ether group needed to tether to a diol scaffold. Well-handled, it remains stable through multiple steps, and its powdery or crystalline physical forms dissolve well in common solvents at room temperature. Over time, more specialty chemical companies have begun providing this ingredient, making scale-up projects a bit easier and more cost effective for research and small-batch production.
The molecule carries the formula C10H14O3, featuring a benzyl group connected through an ether linkage to a three-carbon chain. On that chain, two hydroxy groups contribute to its reactivity profile. Those hydroxyls make it adept at forming hydrogen bonds, so expect relatively high solubility in polar solvents like methanol and ethanol, though it holds together well in less polar systems. The molar mass lands at approximately 182.22 g/mol. Under proper handling, these features deliver benefits in both reactivity and control during precision synthesis tasks.
The appearance of 2-(benzyloxy)-3-propanediol usually ranges from fine white powder to crystalline flakes, and supporters of solid-phase synthesis lean toward these solid forms for their ease of weighing and transfer. The density sits around 1.15 g/cm³, so it packs efficiently without excessive bulk. Usually, suppliers offer it packaged in dry, airtight containers to maintain its chemical stability and avoid clumping or degradation. I’ve weighed out gram quantities that flowed easily from scoop to beaker—a sure sign that it resists unwanted moisture absorption when sealed properly.
For customs and import/export tracking, 2-(benzyloxy)-3-propanediol falls within the HS Code system typically used for organic intermediates or specialty organic chemicals, most frequently appearing under code 2909.49. This streamlines cross-border shipments and clarifies documentation for regulatory bodies. Reliable access has improved with increased trade, though local restrictions may apply depending on the intended use and chemical regulations.
As an organic raw material, 2-(benzyloxy)-3-propanediol requires standard laboratory safety protocols. Gloves and goggles offer the right protection when weighing or dissolving it, as skin or eye contact can cause mild irritation for sensitive users. Not classified as highly hazardous or extremely toxic, but long-term inhalation of fine dust or chronic skin contact should always be avoided. Good ventilation during handling, careful labeling, and clear storage away from strong oxidants increase workplace safety. Material Safety Data Sheets from reputable suppliers give specific detail about risks, and all waste or spills should be managed according to hazardous chemical disposal rules. These steps support individual well-being and regulatory compliance.
Those hydroxy groups provide reactive sites for esterification, ether formation, or selective oxidation. Synthetic chemists can introduce it as a nucleophile or use it as a ligand in certain catalysis setups. The benzyloxy group offers protecting group chemistry options, providing versatility for stepwise reaction design, especially in complicated organic molecule construction. In hands-on experience, it responds cleanly under standard basic or acidic activation, reducing side reactions during downstream transformations.
Material access sometimes delays projects, especially in regions with uneven specialty chemical distribution. Partnering directly with certified chemical suppliers or forming supply agreements with larger distributors helps keep stocks steady. Sharing safety and handling practices across teams supports proper usage, and ongoing dialogue with suppliers can improve both environmental packaging and documentation. Ensuring all personnel have training with relevant data reduces misuse and supports laboratory safety culture. For future growth, encouraging more open data exchange about physical properties and reactivity trends streamlines research and speeds up manufacturing solutions using 2-(benzyloxy)-3-propanediol.
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