2-Benzyloxy-1,3-Propanediol: Properties, Structure, and Chemical Identity

What is 2-Benzyloxy-1,3-Propanediol?

2-Benzyloxy-1,3-propanediol draws attention as an organic molecule featuring two alcohol groups and a benzyloxy substituent. The chemical formula, C10H14O3, points to a structure combining a benzyl ether with a propanediol backbone. Chemists and manufacturers know this compound as a colorless to off-white crystalline solid, recognized for its moderate density and clear molecular identity. A typical HS Code related to intermediates or specialty chemicals often applies, placing this compound in the category for hydroxy compounds or derivatives.

Key Physical and Molecular Properties

This solid stands out for its flake, granular, powder, or pearl form depending on synthesis technique and degree of purity. The density hovers near 1.14 g/cm3, comparable to other propanediol derivatives, so handling doesn’t require extreme precautions around weight or volume calculations. Solubility leans toward polar organic solvents, and thick solutions result when mixed at high concentrations. Storage conditions often involve keeping the material dry and away from high heat, since exposure to moisture or strong acids threatens the benzyloxy group’s integrity.

Chemical Structure and Functional Characteristics

Looking at the structure, 2-benzyloxy-1,3-propanediol offers an ether functionality at the 2-position, with hydroxyl groups waiting at either terminus of the propane chain. The benzyloxy unit promotes lipophilicity compared to basic glycols, shaping both its reactivity and its role in synthesis. In raw material terms, this compound ends up as a protected intermediate for further transformation, often protecting one of the alcohol groups during stepwise organic reactions.

Hazard Information and Safety Considerations

While not classified as highly hazardous, 2-benzyloxy-1,3-propanediol still deserves respect around the lab. Gloves and goggles make up standard defenses against accidental skin or eye contact, especially in powder or finely divided crystal form, which easily become airborne. Literature sources suggest minimal volatile fume release at room temperature, but heating or mishandling may generate small quantities of benzyl alcohol, a mild irritant. Spills and dust require prompt cleanup to avoid slippery surfaces and inhalation risk.

Use as Raw Material and Sourcing Details

As a raw material, this chemical sees action as a building block in organic synthesis, serving pharmaceutical, cosmetic, and fine chemical industries. It plays a part in multi-step routes for complex molecules, where selective functional group protection and deprotection are essential. Sourcing relies on specialty chemical suppliers with transparent documentation on assay, residual solvents, and batch specifications. These details support traceability and meet industry requirements for consistent quality and safety compliance.

Regulatory and Trade Data: HS Code and Compliance

The harmonized system code attached to 2-benzyloxy-1,3-propanediol fits into the category for organic intermediates or ether derivatives of diols. Accurate assignment supports smooth import, export, and customs clearance. Requests from clients or partners for documentation about origin, purity, and certificate of analysis come up often, especially with increased attention to regulatory scrutiny in pharmaceutical and specialty processing environments.

Conclusion: Practical Experience and Future Needs

From my experience handling compounds like 2-benzyloxy-1,3-propanediol, reliable storage and documentation prove just as important as understanding its reactivity. Facilities value transparent supplier practices above all, especially as regulations keep tightening. Research projects or production lines involving this chemical benefit from proper training and hazard awareness, rather than reliance on blanket statements or unverified technical sheets. Teams that treat every drum or flask of product with diligence often avoid incidents and costly interruptions. Above all, working with specialty chemicals like this one highlights the ongoing need for up-to-date safety protocols and responsive supplier partnerships.