2-(4-Chlorophenyl)-2-methylpropanol holds its ground in industrial chemistry circles because it acts as a useful raw material in different synthesis routes. Folks in chemical manufacturing and research often come across this compound when they talk about intermediates for pharmaceuticals or specialty chemicals. Its structure stands out through a central carbon, bonded to both a methyl group and a 4-chlorophenyl ring, finishing off with a hydroxyl group. This configuration influences both how it reacts and how it behaves in storage and production settings.
Looking at this compound, you get a white or off-white solid under room conditions. It forms in crystal-like flakes, but some batches might show it as fine powder or occasionally as granules, depending on processing. A sharp, faint odor comes with higher concentrations. Not readily soluble in water, it usually dissolves with organic solvents like ethanol or acetone, making it easier to handle in lab or plant environments.
Density rests around 1.1 to 1.2 grams per cubic centimeter, putting it with other organic solids used in similar industries. The melting point usually lands between 70 and 75 degrees Celsius. No significant volatility at ambient temperature, which makes spills less risky from an inhalation perspective but always requires ventilation and care.
The IUPAC name for this compound breaks down its elemental structure and helps with identification across databases and regulatory documents. Structurally, it’s recognized as 2-(4-Chlorophenyl)-2-methylpropan-1-ol, with a formula of C10H13ClO. Chemically, the molecule marries a chlorinated aromatic ring to a tertiary alcohol backbone. In practice, this arrangement supports both stability and a strong reaction potential, depending on what functional group is targeted during synthesis.
Manufacturers focus on purity levels above 98% to support consistent outcomes in chemical reactions. Physical inspections center on color uniformity, checking for absence of yellow or brown hues. Crystals, solid flakes, or pearl-shaped bulk shipments travel in sealed drums to keep away moisture and contamination. In labs, you’ll often find it as a fine powder due to the need for quick dissolution in solvents during reactions or testing.
For customs and international transport, the Harmonized System (HS) Code most often falls under 2906, aligning it with phenols and their derivatives. Folks shipping this compound must confirm their documentation: improper codes slow down clearances or draw regulatory questioning. As a specialty chemical, it’s subject to compliance checks in different regions, with Europe and North America placing careful review due to its use in pharmaceutical settings.
Storage rooms should be cool, dry, and shaded from sunlight. Open containers only under fume hoods and seal tightly after each use. Contact with skin and eyes should always be avoided—this isn’t just standard practice but proves especially relevant here. Nitrile gloves, safety goggles, and lab coats form a basic toolkit for safe handling. If you spill it, scoop into a chemical-resistant container rather than sweeping up dry, reducing risk of dust inhalation or skin contact.
As with many chlorinated aromatic compounds, 2-(4-Chlorophenyl)-2-methylpropanol carries toxicity warnings. Direct contact irritates skin, eyes, or mucous membranes. Fume inhalation, though less likely during proper handling, leads to respiratory irritation. Chronic exposure data remains limited, but guidelines recommend minimizing exposure and using only as required for specific synthesis tasks. Waste and leftover raw material go through proper hazardous waste streams, never down a drain or into local trash.
Large-scale producers turn to this compound because it enables routes into pharmaceuticals like clofibric acid derivatives, antihypertensives, or research-grade specialty chemicals. The secondary alcohol group, activated by the aromatic chlorine ring, offers a launching pad for further functionalization, so manufacturers like the versatility. Small changes upstream—slight impurities or altered densities—cascade into slower reaction times or off-spec final products, underscoring the need to check every batch.
Wastewater from reactions using chlorinated aromatic alcohols raises concerns in local water treatment, as some residues linger in the environment. Professional outfits use closed-loop systems or activated carbon filtration to catch and treat any by-products, and regulatory agencies keep close tabs on discharge. Tracking and traceability audits for safety and compliance stretch from raw materials to intermediates and final products, a practice that not only protects workers but keeps communities safe.
Knowledge gaps sometimes lead to improper mixing, exposure, or waste disposal, especially in settings with newer staff or less technical training. Regular workshops on chemical safety, combined with proper labeling and easy-to-understand documentation, go a long way. I’ve walked through labs and plant rooms over the years where clear signage, well-maintained PPE, and an open-door policy for questions make all the difference. Even with the most stable and familiar substances, active attention to detail ensures everyone gets home safe without accidents.
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