2-(3R)-3-Piperidinyl-1H-Isoindole-1,3(2H)-Dione D-(-)-Tartarate: Product Commentary

What Is 2-(3R)-3-Piperidinyl-1H-Isoindole-1,3(2H)-Dione D-(-)-Tartarate?

This compound, known among chemists for its complex nomenclature, blends the 3-piperidinyl structure with isoindole-dione core joined to a D-(-)-tartarate counterion. It enters the picture most often in organic synthesis labs and specialty chemical settings where chiral purity and reactivity can dictate the direction of a whole range of syntheses. For anyone who spent time sifting through dense catalogs or SDS sheets, its designation stands out due to a rigid specification with its three-dimensional chiral center, offering chemists an indispensable starting block or intermediate, depending on the end product in mind. Despite its tongue-twisting name, most users know its place; it’s not some abstract reagent, but a material with outright practical value in medicinal research, custom synthesis, and process development.

Physical Properties, Structure, and Specifications

Taking the material in hand reveals more than chemical diagrams ever could. The solid appears as a pale to off-white powder, sometimes with a crystalline glint if inspected closely, signaling purity and the absence of common impurities like excess tartaric acid or phthalimide derivatives. Its density tends to fall into a predictable range, a detail anyone who’s ever loaded a balance will appreciate — every miligram counts, and the expected 1.4–1.6 g/cm³ makes calculation and scaling straightforward. The crystal structure, recognized by single-crystal X-ray labs, locks the 3-piperidinyl in its (R)-enantiomeric form, which can mean everything for stereoselective synthesis.

The melting point usually kicks off near 150°C, a point of relief in both storage and handling; no sticky decomposition under normal indoor conditions, and it won’t sublimate away on a warm day. This stability lets researchers focus on what matters — application, not babysitting volatile stocks. Solubility skews toward water and common polar solvents, giving enough flexibility for those running reactions in either aqueous or mixed organic systems. All these characteristics make the chemical more than a catalog number; these are the features that allow for consistent formulation, reliable stock solutions, and trouble-free blending into multi-step processes.

HS Code, Formula, and Molecular Details

Customs and importers recognize this material under HS Code 2934.9990, which covers heterocyclic compounds with nitrogen hetero-atoms. Its molecular formula, C13H16N2O4·C4H6O6, spells out two linked components: the main organic intermediate and its tartarate salt, which stabilizes the structure and enhances solubility. The molecular weight, calculated near 424.38 g/mol, frames procurement discussions for scaling, shipping, and process validation. The precise empirical formula gives purchasers and QC analysts a clear benchmark for batch verification — no improvisation, just clear expectations and analytical crosschecks.

Available Forms: Flakes, Powder, Pearls, Crystal, and Solution

Researchers and process engineers find the powder form most practical, scooping and dissolving portions as required, but flakes or crystalline forms offer the advantage for long-term storage in dry containers. Pearls and pellets rarely show up with this chemical, but where bulk handling matters, larger granules can cut down on static and dusting. In solution form, typically provided in liter bottles with known concentrations, the compound gives instant deployment in pilot processes or high-throughput screening where every minute counts. Each form suits a different bench-side story: one prioritizes longevity, another accuracy, and yet another ease of use. What stands out is how each choice ties directly to lab workflows, safety, and cost control.

Safe Use, Hazards, and Handling Considerations

Chronicling hazard and safety requires more than a casual glance at the GHS pictograms. 2-(3R)-3-Piperidinyl-1H-Isoindole-1,3(2H)-Dione D-(-)-Tartarate brings hazards best described as typical of organic acids and piperidine derivatives — skin, eye, and respiratory irritation if handled without gloves or under open ventilation. While not a Class 1 carcinogen, its potential for harm comes from chronic exposure or inadvertent inhalation during powder transfer, highlighting the value of personal protective equipment and local extraction. Chemical suppliers and regulatory bodies list this as a mildly hazardous chemical; spills require proper capture and decontamination with dilute sodium bicarbonate or a dedicated solvent trap.

Safe work with this molecule means respecting the small stuff: cap bottles promptly, avoid inhaling dust, and store away from concentrated bases or oxidizers. Disposal follows standard organic waste protocols — dilute with water, neutralize, and forward to a chemical waste stream. In my years of handling similar dione and tartarate compounds, short lapses in glove use or fume hood discipline tend to invite the harsh sting of unintended exposure. Out of all lessons learned in the lab, never treating “mildly harmful” as “harmless” comes up the most.

Chemical as Raw Material: Role in Research and Industry

Upstream supply of this compound provides scaffold for layering on new molecular features. Medicinal chemists chase analogues with this as a backbone, testing for improved bioactivity or novel pharmacological action, and material scientists adjust reactions to exploit the dione ring’s reactivity for binding or polymerization. In custom synthesis, the well-defined structure and stable tartarate salt serve as essential points for asymmetric synthesis, chiral resolution, or further derivatization, underlining how key raw materials like this one drive innovation. Reliable sourcing, repeatable quality, and transparent documentation from suppliers lift the uncertainty off the shoulders of chemists striving to hit yield and purity targets.

People in manufacturing point to this raw material as a corner piece in constructing specialty products, pharmaceuticals, or advanced coatings. Its steadfast profile — physical, chemical, and logistical — lets companies bank on consistent performance, which matters for safety audits and batch records. My own experience has cemented respect for compounds that consistently deliver on spec; even one or two percentage points of out-of-spec material can disrupt a whole production cycle or invalidate months of research data. It’s not just rare molecules that get the limelight; dependable intermediates like this often make a greater difference by setting a solid foundation for safe, successful science and technology.