This compound, known as (+)-2,3-Dibenzoyl-D-tartaric acid, stands out within the family of organic tartaric acid derivatives. Chemically, it belongs to the class of dicarboxylic acids, featuring two benzoyl groups attached to the core tartaric acid skeleton. Its molecular formula reads C18H14O7, with a molecular weight of 342.30 g/mol. Its appearance often draws attention—usually a white or off-white solid, this material may show as fine powder, crystals, or rougher flakes, depending on processing and storage.
(+)-2,3-Dibenzoyl-D-Tartaric Acid does not dissolve easily in water, which sets it apart from some relatives in the tartaric acid group. Organic solvents like methanol, ethanol, and acetone encourage greater solubility, a key benefit for labs that operate with these common chemicals. At room temperature, the material feels dry to the touch and retains a firm crystalline structure. The melting point usually hovers around 181–185 °C. For chemists, specific gravity averages close to 1.43 g/cm3. The sharp crystalline nature and clean color aid identification, while the dense texture comes from the two benzoyl groups enhancing molecular packing. This chemical remains stable in dry air, yet keeping the container tightly sealed helps to minimize moisture uptake.
The molecular structure shows two benzoyl (C6H5CO) groups linked to the tartaric acid core at the 2 and 3 positions, highlighting both symmetry and chirality. With two carboxylic acid functionalities and two aromatic rings, the structure offers a unique balance between hydrophilic and hydrophobic elements. These features make it attractive for chiral resolution processes, as its specific configuration (the D-enantiomer) allows selective interactions.
Molecular Formula: C18H14O7
Molecular Weight: 342.30 g/mol
Melting Point: 181–185 °C
Density: Approximately 1.43 g/cm3
Appearance: White/off-white solid; powder, flake, or crystalline forms
HS Code: 2918190090 (based on international customs classification for carboxylic acids and derivatives)
Production and storage practices lead to variations in texture and shape. The most common presentation comes as a dry, flowable powder, though larger pearl-like beads and glassy flakes appear in some lots. In a lab setting, the substance fills glass bottles or thick plastic containers, each lined to prevent moisture intrusion. Bulk lots might ship in composite drums, lined and sealed for safety in transit.
The typical raw material pathway begins with D-tartaric acid and benzoyl chloride, using a controlled reaction that ensures the specific (+)-enantiomer forms in high yield and purity. This material finds utility in chemical synthesis—most practitioners turn to it during chiral separations, where it helps split racemic bases or amines by forming salts that allow for isolation of one mirror-image form. This property supports pharmaceutical production, where the regulatory environment puts a premium on single-enantiomer ingredients. The education sector also values it: chemistry instructors use this acid to demonstrate stereochemistry in action.
Even with its stable profile, (+)-2,3-Dibenzoyl-D-Tartaric Acid asks for careful handling. Like other organic acids, it may cause skin or eye irritation after direct contact, so gloves and protective goggles never feel like overkill. Inhaling dust creates similar risks, calling for dust masks or fume hoods during measuring and transfer. Disposal must follow chemical waste protocol, as even relatively benign organic acids can disrupt wastewater balance. The product does carry a hazardous material tag for transportation, flagged under UN numbers established by local and global agencies, and its HS Code sits within globally recognized customs guidelines for dicarboxylic acids.
This acid plays a crucial role when separating and synthesizing chiral drugs, where purity requirements are strict, and the margin for error runs low. My own experience echoes the broader industry trend: mounting regulatory scrutiny in drug manufacturing means labs demand both reliable performance and unquestioned provenance for all raw materials. Market shifts in upstream benzoic acid or tartaric acid pricing directly affect the cost and availability of this compound. This impacts everything downstream, from the cost of research compounds to the unit price of mass-produced medicines.
Process improvements can make a real difference. Automated powder handling and closed-system dissolving systems reduce exposure during weighing and mixing. Education around proper storage and safe handling keeps incidents low, while regular inspections spot caked powder or moisture problems before they affect purity. Substitute packaging, such as moisture-scavenging linings, helps extend shelf life and cuts down on waste from spoiled lots. Open communication between labs and suppliers about quality expectations and batch certification means both science and safety keep pace with demand.
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