2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol stands out as a specialized synthetic compound known for its intricate molecular structure and functional properties in chemical, pharmaceutical, and research industries. People often encounter this substance as an intermediate during manufacturing of advanced organic materials or medicinal agents. A distinctive aspect of this compound is the combination of a 7-chloro-2-quinolinyl group and a hydroxypropyl-phenyl moiety, creating a large, multi-functional molecule with unique chemical reactivity and solubility features. From personal lab experience, working with compounds like this one means regularly considering how aromatic rings and halogenation (the chloro group) influence reactivity, melting point, and safety procedures.
This compound’s molecular formula stacks up as C26H24ClNO2. Each section of the molecule brings different characteristics: the quinoline ring system creates flat, aromatic properties, the chloro substituent alters both electronic character and reactivity, and the hydroxypropyl group introduces polar interaction potential with solvents. Its chemical structure—bulky with several phenyl connections and a tertiary alcohol—leads to solid crystalline or powdery appearances under typical room conditions. Access to a structure like this opens doors to targeted chemical synthesis because the reactive points—such as the hydroxy group and ethylene bridge—let chemists alter the core for different derivatives or pharmacological applications. This flexibility in synthesis lets research teams adapt the molecule for broader applications, which proves vital as novel therapeutic areas emerge.
The compound commonly occurs as an off-white or pale-yellow crystalline solid or powder. Density typically falls between 1.2 and 1.4 g/cm³, which reflects its moderate molecular weight and the presence of chlorinated aromatic rings. The presence of both polar (hydroxy) and nonpolar (aromatic, chloro) groups impacts solubility: it dissolves in common organic solvents such as DMSO, DMF, ethanol, and, to some extent, chloroform. Water solubility remains limited due to the robust hydrophobic core. Based on laboratory handling, fine powders like this flow easily but compact under pressure, and forming flakes or larger crystals depends on recrystallization approaches and cooling rates. Purified samples display sharp melting points, a sign that the structure resists thermal breakdown until higher temperatures are reached. This trait makes storage easier and reduces the risk of accidental decomposition during transport or handling.
Producers offer the compound as a solid—usually powder, flakes, or small crystals—in various container sizes, from grams for laboratory use to industrial quantities stocked in kilograms. Bulk shipments get packed in inert atmosphere bags due to sensitivity of the chloro and hydroxy groups to prolonged light or moisture. Crystal sizes range from fine powders to larger, pearl-like forms, depending on crystallization technique and purity requirements. Researchers often prefer smaller mesh sizes for reaction consistency, while industrial end-users might look for more compact, dust-limiting forms. These options benefit everyone in the supply chain, cutting down on processing times or filtering challenges in bench-top and scaled-up reactions. Color and appearance can signal quality: clean pale-gray to white powder points to purity, while discoloration hints at potential degradation or contamination from manufacturing steps.
Shipments usually classify this molecule under HS Code 2933.39, which covers heterocyclic compounds with nitrogen hetero-atom(s) only, especially those containing quinoline rings. Customs compliance here matters not just for tariffs but for ensuring end-users know which paperwork and hazard labels belong with every drum or sample. International moves require correct documentation due to the chlorinated aromatic system, which sometimes raises regulatory eyebrows as potential precursors for pharmaceuticals or specialty chemicals. A clear HS Code streamlines import/export checks, helping companies reduce border hold-ups and keep research on schedule.
As a material, 2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol exhibits remarkable chemical stability under standard storage conditions when kept cool, dry, and protected from prolonged UV exposure. The chloroquinoline fragment resists casual oxidation, though extended storage—especially in the presence of air and light—invites slow degradation or isomerization. Acidic or basic media can foster hydrolysis or addition reactions at the hydroxypropyl junction; from my own handling, solutions in basic solvents should be made fresh to prevent breakdown. Reactivity centers around the tertiary alcohol and the activated aromatic rings, making the compound a solid candidate for further functionalization in research labs or for polyethylene glycol conjugates. Avoiding excess heat and moisture during use and storage dramatically preserves both purity and shelf-life.
End-users select from several forms: dry powder suits synthesis and reaction-stage controls; flakes or crystalline mass work for batch crystallization or separations; dissolved forms (typically in ethanol or DMSO) support dosing for in-vitro or analytical applications. This variety gives chemists a handle on the material based on required workflow—making it easier to weigh, dissolve, or dilute. Fine powder can present inhalation risks, so an enclosed workspace brings peace of mind. Large batch users appreciate pre-dissolved solutions, which cut down on manual measuring and reduce variability in research results. Material form impacts flowability, ease of transfer, and how quickly the substance reacts or dissolves during experiments or production blending.
This compound’s structure means users treat it with prudent caution. The chloroquinoline portion carries toxicity risks if inhaled or ingested; typical safety data sheets recommend gloves, eye protection, and, where scale permits, use inside a ventilated fume hood. The powder form can dust easily, making respiratory PPE especially important for larger scales or repeated handling. Potential hazards include eye or skin irritation, and accidental ingestion can cause gastrointestinal or nervous system effects due to aromatic and halogenated components. My own habit is to set up a spill kit and keep clean-up materials on standby whenever handling substances in this structural class. The hydroxy group, while less reactive than primary alcohols, can be targeted by strong oxidants or acids, so storing away from such reagents secures both operator and material integrity. Waste disposal needs to match local chemical hazardous material protocols; containers must close tightly to prevent leaks and environmental release.
Raw materials for 2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol trace back to chlorinated quinoline derivatives, styrenic intermediates, and specialized alcohol precursors—often requiring multi-step synthesis in controlled facilities. Experienced chemists value the compound’s versatility: it fits as a building block in drug design and evaluation, material science, and specialty pigment or sensor development. Functionality at the tertiary alcohol lets researchers attach bioactive groups or solubilizing chains, supporting development in both chemical and life sciences. At the same time, producers must account for purity standards, stability during storage, and compliance with evolving chemical safety standards. Strong demand in pharmaceutical research and industrial synthesis means quality control gets intense scrutiny, both for batch consistency and for meeting end-use regulations, especially around healthcare or environmental impact.
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