(1S,4R)-4-Amino-2-cyclopentene-1-methanol tartrate brings a distinct profile as a specialty organic compound, frequently valued in pharmaceutical raw materials development. Its core structure features a cyclopentene ring, an amino group attached at the fourth position, and a methanol functional group branching off the first carbon. The tartrate component arrives paired as a salt, improving stability and solubility in certain laboratory and industrial environments.
This compound presents itself as a solid, commonly encountered as crystalline powder, but sometimes as distinct flakes or small pearls, depending on the synthesis route and purification stage. You’ll notice a white to off-white hue, with good flow in powdered or granular form, making material handling standard practice for chemical suppliers. Its density aligns with many small organic salts, sitting in the expected range for amino alcohol tartrates around 1.32 to 1.37 g/cm3. Solubility in water lets researchers prepare accurate solutions for biochemical assays, and this material remains stable under normal storage with dry, room temperature conditions.
As you examine the molecular structure, you find the backbone centers on a five-membered cyclopentene ring, with an amino group (NH2) branching from the fourth carbon, and a methanol group (CH2OH) extending from position one. The tartrate comes from the tartaric acid portion, often present as the monohydrate or dihydroxybutanedioate salt, giving improved solubility and crystalline form. This molecular structure—C6H11NO paired with C4H6O6—results in an overall formula of C10H17NO7. This configuration matters most when you’re aiming for high purity in pharmaceutical syntheses, since the chiral centers at positions one and four drive selective reactions later down the manufacturing line.
Specifications for (1S,4R)-4-Amino-2-cyclopentene-1-methanol tartrate focus on chemical purity, typically requiring 98% or higher for research or production. The compound falls under HS Code 29224999, marking it as an organic base with oxygen function, not elsewhere specified. Quality control relies on thorough moisture content testing (Karl Fischer titration is standard) and specific optical rotation, since stereochemistry influences end product effectiveness. You might find the material labeled as “for research and manufacturing use only,” with typical unit sizes ranging from grams to kilograms.
Safety remains front of mind for anyone preparing or storing (1S,4R)-4-Amino-2-cyclopentene-1-methanol tartrate. While the compound does not meet criteria for high acute toxicity, it can act as an irritant, and powder may become airborne during weighing or transfer. Direct skin or eye contact should be avoided—lab coats, gloves, and safety glasses come standard. The compound classifies as “harmful if swallowed or inhaled” due to possible central nervous system effects, reinforcing the need for controlled ventilation or using a fume hood. Storage in sealed, amber containers away from light and moisture preserves chemical integrity, and good inventory control helps prevent wastage. Spill cleanup follows industry norms: collect solids with absorbent materials, ventilate air, and fully clean surfaces to avoid residual contamination.
Manufacture of (1S,4R)-4-Amino-2-cyclopentene-1-methanol tartrate starts with cyclopentene as a core hydrocarbon, adding amino and methanol functional groups through planned organic transformations. Tartrate salt formation usually closes the synthesis, yielding a stable, isolatable powder with solid crystalline properties. Sourcing quality raw materials—especially starting cyclopentene and high-purity tartaric acid—matters for consistent product outcomes. Reagents get screened for impurities, trace metals, and unwanted chiral contaminants, as small differences can disrupt downstream pharmaceutical processes. Analytical support, using NMR, mass spectrometry, and chiral HPLC, anchors manufacturing and final product release.
Research groups push to improve both process safety and environmental footprint. One common approach reduces the use of hazardous solvents during initial functional group additions; greener solvents or solvent-free protocols cut toxic emissions and simplify waste management. Wastewater stands as the largest process byproduct, and filtration or in-line purification systems help recover valuable materials, while reducing disposal needs. For labs and factories, robust training in chemical handling and emergency procedures minimizes accident risks—even small spills receive prompt attention with specialty absorbent materials, protecting both workers and the environment. Sourcing high-purity starting materials from certified suppliers improves both safety and efficiency, reducing the need for repeated purification or rework.
You find (1S,4R)-4-Amino-2-cyclopentene-1-methanol tartrate in key stages of pharmaceutical synthesis, particularly in developing advanced intermediates. Its chiral centers make it indispensable in synthetic pathways for complex molecules, as each stereochemical detail carries forward into final medicinal products. Companies involved in R&D or small-batch manufacturing appreciate detailed specification sheets, certifying both physical and chemical properties before use. From my perspective, as demand for safer and more effective pharmaceuticals rises, so does the value of well-characterized, high-quality raw materials like this one.
Chemical Name: (1S,4R)-4-Amino-2-cyclopentene-1-methanol tartrate
Molecular Formula: C10H17NO7
HS Code: 29224999
Appearance: White to off-white crystalline powder, can occur as flakes or pearls
Density: 1.32–1.37 g/cm3
Solubility: Freely soluble in water
Other Properties: Stable under normal conditions, slightly hygroscopic, safe when handled using standard chemical hygiene practices
Hazards: Harmful if swallowed or inhaled, may irritate skin and eyes
Raw Materials: Cyclopentene derivatives, tartaric acid, methanol-based reactants
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