(1R,2R)-(+)-Cyclohexane-1,2-diamine L-tartrate stands out as a chiral diamine salt valued across pharmaceutical and chemical industries. Chemists tend to turn to this compound for its role in creating asymmetry in synthesis, which unlocks novel pathways in drug development and fine chemical production. Its molecular formula lands at C10H22N2O6, with a molar mass clocking in at roughly 270.29 g/mol. Looking closer at its structure, it’s made from the pairing of (1R,2R)-(+)-cyclohexane-1,2-diamine with L-tartaric acid, building a crystalline, chiral salt that interacts in predictable ways with reagents and solvents. As a raw material, it commonly arrives as a fine, solid powder or as flaky, white to off-white crystals. Sometimes, the substance appears as small pearls or granules, but never in a liquid state at room temperature. Its density hovers near 1.3 g/cm3, supporting ease of handling and weighing during lab work or production scale-ups.
During hands-on experience, I find this compound shows impressive stability under recommended storage conditions. It resists degradation under standard room lighting and temperature, provided it stays sealed from moisture and excessive heat. The substance remains odorless and free-flowing, simplifying accurate transfer and precise measurement, whether you’re preparing small analytical samples or larger syntheses. As a crystalline solid, it dissolves readily in water, methanol, or ethanol, building clear solutions essential for many reaction setups or analytical procedures. When converting to a solution, the density shifts more toward the solvent side, which matters for those conducting stoichiometric calculations. Users will want to make sure glassware stays dry and free from acidic or basic contaminants to preserve the quality of the compound. It also pays to avoid oxidizing agents in the same workspace, since these could trigger unwanted side reactions or safety incidents.
Chemists identify (1R,2R)-(+)-Cyclohexane-1,2-diamine L-tartrate by its clear, defined molecular geometry. The diamine portion, derived from trans-cyclohexane, provides two primary amine groups at the 1 and 2 positions of the ring, both locked into the (R,R) stereochemistry. L-tartrate acts as the counter-ion, conferring further chirality and allowing for strong hydrogen-bonding networks in both solution and solid state. This structure takes on a C6H14N2 fragment paired with the L-tartrate, which is C4H6O6. Reliable for asymmetric inductions and chiral auxiliaries, this compound plays a part in preparing a wide range of pharmaceuticals and agrochemicals, and practical users appreciate its predictable reactivity in both lab-scale and industrial reactions. Compared to unstable organic salts, this product stands up well during storage, retaining its crystalline form and chiral purity even after repeated use. This brings undeniable value for repeated syntheses or long-term studies, since replacement or recalibration becomes a rare concern.
Shipments of (1R,2R)-(+)-Cyclohexane-1,2-diamine L-tartrate often arrive with a purity standard of at least 98%, and typical specifications share allowable ranges for water content, residue on ignition, melting point (usually between 185°C and 192°C), and optical rotation. These detailed analyses build confidence for pharmaceutical quality control, especially when enantiomeric purity comes under regulatory scrutiny. The most accessible form for research and production remains the crystalline powder, though some suppliers provide flakes or compacted pearls for specific blending needs. Users gravitate toward this solid form thanks in part to its low bulk density and resistance to caking. In aqueous or alcoholic solutions, operators should expect transparent liquids, critical for integrating with catalytic reaction workflows or for use in chiral resolution steps. Every container ships with clear safety labeling and documentation tracking CAS number 107619-73-8, providing traceability from manufacturer to end-user.
On the regulatory front, the product ships under HS Code 2922.29, covering “amino compounds with oxygen function.” Clear coding simplifies customs processes and supports international logistics for materials destined for chemistry labs, pilot plants, and manufacturing facilities. As a raw ingredient, (1R,2R)-(+)-Cyclohexane-1,2-diamine L-tartrate often finds a place in the early stages of pharmaceutical synthesis, catalysis research, and materials discovery. Over the years, I’ve seen it adopted in the crafting of complex, optically-pure molecules, where its chiral backbone helps build layered chemical structures that resist racemization. Manufacturers gravitate toward this diamine salt because it retains excellent physical integrity throughout shipping, storage, and use.
Handling a substance with primary amines such as this compound brings routine safety considerations common to organic chemistry labs. By industry practice, workers suit up with nitrile gloves, goggles, and lab coats, since direct contact can irritate the skin or eyes. Inhalation, though less likely with the solid form, could bring discomfort, so proper ventilation matters during weighing or mixing. This chemical does not build up in the body or break down into persistent organic pollutants when managed according to standard waste disposal protocols. Spills clean up with sweeping or vacuum systems that keep powders from dispersing into the air. Product safety sheets highlight the need to avoid ingestion, inhalation of dust, and prolonged exposure, but the substance doesn’t rank among highly hazardous chemicals. For shipping or storage, transport containers must remain dry and closed tightly to protect both users and material quality. Waste management follows standard local rules for amine-containing chemicals, involving designated collection bins and approved incineration or chemical neutralization processes.
In daily operations, I see (1R,2R)-(+)-Cyclohexane-1,2-diamine L-tartrate shaping high-value sectors. Pharma labs lean on it for building selective catalysts and resolving agents critical to synthesizing medicines where a single enantiomer matters for safety and efficacy. Agrochemical teams turn to its chiral influence in forming crop protection molecules. Its ready availability as a solid or solution saves time, lowers error rates, and delivers clean results—as long as teams stick to best practices for storage and handling. With recyclable containers and robust physical stability, it fits both small-scale research and full-scale production, reflecting a blend of chemical ingenuity and practical know-how in the world of raw materials and life sciences.
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