1-Cyclohexyl-1-Phenyl-3-Piperidine Propanol Hydrochloride: Profile, Properties, and Industry Context

What Is 1-Cyclohexyl-1-Phenyl-3-Piperidine Propanol Hydrochloride?

1-Cyclohexyl-1-Phenyl-3-Piperidine Propanol Hydrochloride stands out as a synthetic chemical compound shaped by both piperidine and propanol characteristics. Its structure pairs a cyclohexyl and phenyl group joined to a piperidine ring, held together by a propanol backbone and stabilized as a hydrochloride salt. Chemists know this class for its stable, crystalline properties and potent physical presence in a range of raw material applications, especially in fields handling chemical synthesis or pharmaceutical research. The arrangement of nitrogen in the piperidine ring, plus the rigidity of the phenyl and cyclohexyl moieties, give this compound a unique blend of steric and electronic effects, making it a versatile intermediate for certain targeted syntheses.

Physical Structure and Appearance

In terms of form, 1-Cyclohexyl-1-Phenyl-3-Piperidine Propanol Hydrochloride typically presents as an off-white to white crystalline solid at room temperature. The hydrochloride yields a stabilized version suitable for long-term handling and storage compared to many free base organics. Density often registers above 1 gram per cubic centimeter, reflecting a tightly packed crystal lattice, which translates to a substantial bulk for shipping and mixing. Unlike amorphous powders, the flakes or fine pearls maintain their integrity well, reducing airborne dust during handling. Melting points often fall within the medium range for organics, suggesting moderate heat tolerance before phase transition, which proves key for controlled reactions or storage stability.

Chemical Properties and Safety Information

The compound’s molecular formula organizes as C20H31NO • HCl, with a molecular mass generally sitting around 337 to 339 g/mol, depending on hydrate content. As a hydrochloride, it dissolves well in polar solvents, including water and ethanol, allowing formulation in aqueous or alcoholic solutions for reaction or testing. In these solvents, the hydrochloride acts as a proton donor, which influences pH and can impact side reactions. Chemists classify this material as a hazardous chemical—contact with skin or inhaled dust poses risks such as irritation, so gloves, goggles, and adequate ventilation prevent exposure. Material safety data points to possible central nervous system effects at significant levels, meaning accidental ingestion or improper disposal puts workers and the environment at risk. Labeling under GHS aligns with ‘harmful if swallowed’ and ‘irritant’ status, and users must store it securely to avoid cross-contamination with incompatible materials.

Role as a Raw Material and Industrial Applications

Handling as a raw material, 1-Cyclohexyl-1-Phenyl-3-Piperidine Propanol Hydrochloride feeds into several sectors. Research labs prize it as an intermediate for complex molecule creation, with the scaffold useful for building blocks in medicinal chemistry, particularly where nitrogen-containing cycles are desired. Its solubility profile and crystalline stability allow simple weighing, transfer, and solution preparation, a noticeable advantage for precise synthetic steps or when scaling up pilot processes. While some chemical suppliers sell this as powder or flakes, others offer it dissolved in compatible carriers to suit automated systems for high-throughput operations.

HS Code, Specifications, and Compliance

Traceability through trade requires identification by Harmonized System (HS) Code. This compound usually aligns with codes for organic base salts, something like 2933.39, though specific assignments vary by national customs. Industry buyers expect reporting on purity, typically upwards of 98%, plus impurity profile, water content, and bulk density. Suppliers must also document batch traceability, proper UN chemical labeling, and hazard statements, which builds confidence among buyers and helps satisfy regulatory audits. Shipping as a powder, flake, or solid bulk demands UN-approved packaging, moisture barriers, and temperate storage away from oxidizers, acids, or direct sunlight to preserve quality and reduce risk.

Solutions and Safe Handling in Operations

Any operation using 1-Cyclohexyl-1-Phenyl-3-Piperidine Propanol Hydrochloride benefits from regular safety training, clear signage, and ready access to safety data sheets (SDS). Secondary containment in labs or production lines prevents accidental releases—spill kits and eyewash stations stand ready for immediate response. Waste streams containing this compound must route through chemical neutralization or approved disposal partners, never into ordinary waste or drains, given its hazardous status. Proper ventilation, PPE, and environmental controls cut down risk, and digital compliance systems help managers monitor stock levels, expiration dates, and storage conditions.

Molecular Insight and Chemical Discussion

A close look at the molecular structure shows a compact core where the cyclohexyl and phenyl rings crowd the piperidine nitrogen. This arrangement shields the amine, which sometimes alters reactivity compared to unbranched piperidines. The propanol arm carries the hydrochloride’s proton, offering a site for salt formation and boosting aqueous solubility. This mix of hydrophobic and hydrophilic features influences partitioning behavior, which matters for formulation and extraction steps in synthetic protocols. For those developing new routes or scaling up, these molecular quirks call for careful process design and pilot batch testing to manage solubility, crystallization, and purification steps.

Storage, Bulk Handling, and Environmental Impact

Facilities that warehouse this material rely on climate-controlled storage with minimal humidity and stable temperatures to check degradation or clumping. Since it’s not volatile, risk of vapors stays low, but dust suppression remains a constant focus. Bulk shipments may arrive in drums, lined containers, or smaller jars for high-value laboratory work. From an environmental standpoint, discharge into water systems prompts immediate corrective action since the compound can persist and potentially harm aquatic organisms or disrupt wastewater treatment. Operations aiming for lower impact invest in closed-loop systems, vapor recovery units, and advanced waste filtration, which not only protect people but help meet stricter regulatory requirements.

Industry Context and Future Discussion

With increasing attention on chemical safety and transparent sourcing, producers now highlight not just technical specs, but origin, trace impurities, and full hazard labeling on every order. Recent scrutiny from health and environmental agencies puts pressure on the supply chain to manage every stage—synthesis, storage, delivery, and disposal—under strict controls. Increasingly, buyers select suppliers with track records for safe shipping, rigorous documentation, and eco-friendly packaging. Developing greener synthetic routes or biodegradable alternatives may reshape the raw material landscape, but for now, 1-Cyclohexyl-1-Phenyl-3-Piperidine Propanol Hydrochloride continues to serve a vital role wherever robust, well-structured nitrogen scaffolds are required.