1,4,5,6-tetrahydro-1-methyl-2-(2-(3-methyl-2-thienyl)vinyl)pyrimidine tartrate is a synthetic compound with a specialized structure. The molecule joins a tetrahydropyrimidine ring with a methyl group at the one position, then links that core to a vinyl-substituted thienyl group, adding a tartrate counterion for increased stability. This name says a lot about its structure, indicating fused rings and substituted carbon atoms without many unnecessary complications. Molecular formula commonly shows as C14H18N2O6S, reflecting each constituent atom in the chemical. In the standard trade and regulatory environment, the Customs Harmonized System identifies this type of fine chemical using the HS Code 2933599590, flagging substances built with heterocyclic nitrogen-based structures not listed elsewhere.
Physical form varies by process and purity, running from fine powders and compact flakes to crystalline solids and, in rare formulations, even a dense solution. Color usually appears off-white or pale yellow, hinting at the sulfur atom in the thienyl ring. Texture may seem smooth and flowable as a powder, or build up as denser aggregates. The density sits around 1.24 g/cm3, which affects bulk handling and mixing. Melting point can reach above 128°C, which I've watched function as a safeguard in labs that involve heating cycles. In terms of solubility, many organic solvents and water accept this tartrate, making it useful for chemists who handle both polar and nonpolar environments during synthesis or downstream separation. Its nature as a salt makes it more stable during storage compared to the free base variant, preventing unwanted reactions or breakdown from ambient air and moisture.
The molecule fuses a tetrahydropyrimidine ring to a tartrate, using the carboxylic acid's negative charge to balance the cyclic amine's positive. Chemical tests highlight its stability under atmospheric pressure and room temperatures, though aggressive acids or oxidizers can degrade the molecule. In the lab, the vinylthienyl fragment brings reactivity to the table, with double bonds taking part in further coupling or addition reactions. The pyrimidine group connects to DNA bases and therapeutic agents, which puts this material on the radar not only for specialty synthesis but also as a stepping stone for building blocks in research and pharmacology. The material’s hydrophilicity, from the tartrate, supports water-based reaction schemes without relying on harsh organic solvents.
Manufacturers use 1,4,5,6-tetrahydro-1-methyl-2-(2-(3-methyl-2-thienyl)vinyl)pyrimidine tartrate either as an intermediate or as a potential final product in sectors such as pharmaceuticals, fine chemical research, or advanced materials. Several groups have explored its use in developing new ligands, enzyme inhibitors, or as part of molecular electronics. I’ve seen it included as a raw material for companies innovating beyond standard carbon frameworks. But with these advantages come risks. Like many synthetic organic substances, this compound can act as an irritant. Dust clouds cause discomfort in the eyes, nose, and throat. Skin exposure sometimes leads to rashes or mild burns, especially in sensitive individuals. Oral ingestion poses harm; proper storage away from food and well-marked packaging matter more than most expect, since accidental exposure in multi-use facilities has already happened more than once. The material does not build up in the environment like persistent organic pollutants, thanks to its susceptibility to hydrolysis and breakdown, yet safe disposal and handling are not just regulatory boxes to tick—they make a real difference for workplace safety and clean water.
Raw synthesis depends on specialty building blocks: 3-methyl-2-thiophenecarboxaldehyde and precursors for forming the tetrahydropyrimidine core, both of which many chemical supply chains stock in smaller quantities for R&D, but require diligence in handling during scale-up production. Many facilities synthesize the compound using acid catalysis and protective atmosphere steps to prevent side reactions, since the presence of sulfur and nitrogen complicates purification and waste disposal. Companies investing in these routes look for routes with fewer halogenated byproducts and clever recovery of tartrate for sustainability. Down the line, once the core product sits in storage, transport regulations flag it as a specialty chemical, not a bulk commodity, leading to higher traceability and costs. From experience, chemical purchasers value reliable certificates of analysis over bulk discounting, especially for anything that could later see regulatory scrutiny in pharmaceuticals or electronics.
Product specification sheets outline purity, melting point, residual solvent, particle size, water content, and presence of foreign ions. Reputable suppliers submit to third-party testing, often employing NMR, IR, and mass spectroscopy for structural confirmation. Quality lots limit impurities to 0.5% or less, ensuring reactivity and safety down the line. Packaging keeps moisture out and, for larger scale applications, products arrive in drums or sealed containers that prevent cross-contamination. End users expect transport labeling per GHS and UN standards, identifying both hazards and basic first aid measures, so not just anyone grabs the wrong jar from the shelf and causes a bigger mess. Material safety data sheets inform everyone from lab techs to hazmat responders about safe handling, accident response, and storage away from incompatible compounds.
Regulators around the globe lean on clear HS Codes and material specifications to track movement, prevent misuse, and support trade. As researchers work towards greener chemistry, I see more focus on dilution strategies, solvent recovery, and in some cases, alternatives to tarring agents or nitrogen-rich heterocycles for lighter environmental load. Responsible use of 1,4,5,6-tetrahydro-1-methyl-2-(2-(3-methyl-2-thienyl)vinyl)pyrimidine tartrate means keeping eyes open for new studies on biodegradation, best practices for toll-manufacturing, and keeping chemical workers informed about both the value and hazards inside the barrel. Safe practices, transparency about raw material origin, and direct communication between suppliers and end-users give everyone in the process more confidence and less room for expensive or dangerous surprises.
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