1 2-Propanediol 3-amino- (2S)- belongs to a class of amino alcohols commonly used in laboratory and industrial applications. Its IUPAC name marks it as a molecule derived from propanediol with an amino group at the third carbon, locked in the (2S) configuration. This chiral center gives the compound unique biological interactions, influencing its function as a building block in synthetic chemistry. Professionals in chemical research, pharmaceuticals, and specialty manufacturing often turn to this material for its reliable functional groups and stable backbone.
Looking at the molecular level, 1 2-Propanediol 3-amino- (2S)- features a three-carbon chain. Two carbons carry hydroxyl groups, and the third bears an amino group. The general formula stands as C3H9NO2, uniting essential chemical versatility with compact molecular size. Its structure supports wide-ranging reactivity and compatibility with diverse reagents. The presence of the S-configuration can play a crucial role in applications where optical activity makes a difference, such as chiral catalysis or drug development. This configuration often means different biological outcomes compared to its mirror image, directly affecting efficacy and safety in pharmaceutical use.
As a raw material, 1 2-Propanediol 3-amino- (2S)- appears most frequently in crystalline solid or fine powder form. Depending on storage conditions, one can also find it as flakes or in pearl-like granules. It dissolves well in water and reacts with standard acids or bases, creating multiple downstream derivatives. Its specific density generally measures around 1.08-1.15 g/cm³ at room temperature. The melting point typically lies in the range of 40°C to 60°C, though slight variations arise depending on purity levels. This compound displays low volatility, contributing to its ease of handling in both open and closed systems. Maintaining stability under standard conditions, it resists decomposition except under excessive heat or strong oxidizing environments. Chemists and manufacturers value this stability, which lowers labor and storage risks.
Safety forms a core part of working with all chemicals, including 1 2-Propanediol 3-amino- (2S)-. Contact with skin or eyes may cause mild to moderate irritation. Inhalation of dust or fine particles, especially during weighing or transfers, can lead to discomfort. Proper ventilation, gloves, and eye protection reduce this risk. According to current GHS guidelines, the compound sits outside the most hazardous categories but warrants respect for its potential impacts if mishandled. Standard data sheets designate this compound as non-flammable, and it carries neither explosive nor carcinogenic tags in conventional use. The HS Code, crucial for international movement and inventory tracking, often falls under 2922.49—representing amino alcohols and their derivatives. In my experience, robust labeling and locked storage go a long way toward preventing unauthorized access or accidental exposure. Waste from processes involving this compound usually must be treated as chemical waste and should never enter the general drainage system, protecting water sources and the broader environment.
In many laboratories, 1 2-Propanediol 3-amino- (2S)- functions as a reagent, intermediate, or raw material for synthesizing active pharmaceutical ingredients. Its chiral nature makes it a practical choice for asymmetric synthesis routes, where the final product’s handedness affects therapeutic value. Industrial operations harness this molecule for the assembly of custom surfactants, specialty coatings, and advanced composites. Sometimes, companies use it in fine-tuning pH or as a building block in biodegradable polymers. Clear guidelines and best practices ensure consistent product performance whether the material is processed as a liquid, dissolved in solution, or handled as a dry solid.
Awareness of how materials move through the environment matters, especially for specialized chemicals like this one. Although 1 2-Propanediol 3-amino- (2S)- breaks down over time when exposed to natural conditions, concentrated discharge can cause harm to aquatic systems. Facilities must follow local regulations for chemical disposal and maintain proper documentation of handling and storage. Treatment systems and solvent recovery protocols can limit environmental impact, turning waste into a manageable byproduct. Efforts to educate staff about these practices have paid off in my own work environments, cutting incident rates while maintaining compliance and community trust.
End users care a lot about material quality and consistent specification, especially for applications in pharmaceuticals and fine chemicals. Pure samples of 1 2-Propanediol 3-amino- (2S)- show high infrared absorption at key functional group frequencies—an analytical check for identity and purity. Laboratories commonly confirm enantiomeric excess by chiral chromatography before using the compound in critical syntheses. Specifications provided by reputable suppliers typically include melting point, water content, specific density, and impurity profile. Regular testing and batch tracking minimize risk from off-spec delivery, strengthening customer confidence and process reliability.
Managing complex raw materials like 1 2-Propanediol 3-amino- (2S)- means taking stock of safety, quality, and environmental stewardship at every stage. Suppliers offering transparent documentation, robust packaging, and responsive support help reduce risks. Simple procedural training—double-checking labels, securing storage, monitoring for spills—shapes outcomes for teams across manufacturing, academic, and industrial sites. Building solid records of sourcing and usage, along with ongoing hazard assessments, supports both everyday safety and long-range sustainability. Good practice here does more than check legal boxes; it protects workers, product value, and broader community well-being.
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