(±)-1-((2-(3,4-Dimethoxyphenyl)ethyl)amino)-3-(3-methylphenoxy)-2-propanol Hydrochloride stands as an interesting synthetic compound shaped by the union of both organic chemistry finesse and real-world practical use. This substance draws interest mostly in pharmaceutical research and chemical development labs. The molecule brings together a dimethoxyphenylethyl group and a methylphenoxy propanol scaffold, topped off with a hydrochloride for increased water solubility and stability. Labs working with beta-blockers or CNS agents sometimes cross paths with similar compounds, as their structure fits into various research pipelines. City-scale chemical importers and distributors watch the details closely — structure, formula, density, and all — both to ensure compliance with regulations and to guarantee the chemical behaves as expected during analysis or production.
At room temperature, this hydrochloride takes a solid form, frequently appearing as off-white or light beige crystalline powder or flakes. The substance feels slightly gritty between two fingers, and exposure to the air in humid conditions can invite caking. If the container seals tight, the flakes stay free-flowing and manageable even on damp days. The compound dissolves rather well in water due to the hydrochloride, helping out analysts who need clear, aqueous solutions for testing or synthesis. Its molecular formula — C20H28ClNO4 — stacks the numbers: twenty carbons, twenty-eight hydrogens, one chlorine, one nitrogen, and four oxygens. The molar mass tips the scale around 381.9 g/mol, which is significant for measuring out supplies and handling calculations in the lab. Density lands around 1.2 g/cm³, typical for mid-weight organic salts, helping with straightforward volumetric measurements on the benchtop or bulk handling setups. Large crystals sometimes form under slow evaporation, though for most commercial and research applications, folks deal with it in the powder or fine solid state. Odor rarely comes through since amines and phenoxy groups present here do not volatilize easily, so even in larger quantities, the workspace does not carry much smell.
The structure of (±)-1-((2-(3,4-Dimethoxyphenyl)ethyl)amino)-3-(3-methylphenoxy)-2-propanol Hydrochloride highlights an interesting arrangement. A central propanol backbone holds a 3-methylphenoxy group at one end and a chain leading to a 3,4-dimethoxyphenylethyl group at the other, bridging with an amine. Hydrochloride binds ionically to the nitrogen, boosting solubility and thermal stability. The symmetrical (±) configuration points to a racemic mix, so a mix of both left- and right-handed enantiomers lands in the container, unless a supplier works up an optical separation (which does not happen much outside specialized R&D). The methoxy groups tuck electrons into the aromatic rings, changing reactivity compared to simpler phenols or ethylamines, while the methyl group steers the molecule's interactions further.
Quality control checks touch on appearance, melting point, and solubility in water and ethanol. Most reputable suppliers list a melting point range in the ballpark of 135-140°C. Purity reports, assessed by HPLC or NMR, routinely hit above 98%. Moisture content, as determined by Karl Fischer titration, sticks below 0.5% for stable, free-flowing powder. HS Code guides international shipping and customs. (±)-1-((2-(3,4-Dimethoxyphenyl)ethyl)amino)-3-(3-methylphenoxy)-2-propanol Hydrochloride fits under HS Code 2922.50, which covers amino-alcohols, their ethers, esters, and salts — a key detail for import-export paperwork. Most customs offices want to see tight paperwork and unambiguous labeling thanks to the potential for misclassification or process holdups.
This compound surfaces most often as a building block or intermediate. Researchers exploring adrenergic blockers, antihypertensive possibilities, or CNS-active analogs lean on the structure. Its handle as a raw material means it faces batch synthesis, purification, and scale-up steps, so suppliers pay special attention to consistency, safe transport, and reliable analytical results. In terms of personal experience in a synthesis lab, care with powder handling makes all the difference — gloves, bench paper, and vacuum filtration prevent messy situations and unintentional contact. Even with low acute toxicity for many similar amino-alcohols, standard chemical safety applies: avoid ingestion, inhalation, or skin exposure. Eye protection becomes a must, as dusty powders find their way into the air during weighing or transfer, especially in dry environments or with static-prone plastics.
The pages of the Safety Data Sheet (SDS) call out for routine caution: prevent dust, clean spills with water dampened towels, and keep the product in tight bottles away from sunlight. This chemical does not fall under high hazard categories but should never go untracked, both for worker safety and environmental compliance. Training for new staff or students includes reviewing hazardous material markings and correct disposal — seldom tossed into regular trash or sewer due to local regulation and common sense in responsible labs. The hydrochloride form, despite expectations, sometimes brings mild skin irritation, so direct contact without gloves finds most users with red knuckles by the afternoon. As with so many specialty compounds, the burden sits on both producer and researcher to document each step, track batch numbers, and share results with a mindset for accuracy and reproducibility.
From the bench to the loading dock, keeping this hydrochloride in prime condition takes deliberate action. Humidity, sunlight, or uncertain container seals spell trouble over weeks or months, with caking, color change, or decomposed product as real-world consequences. Refrigerated storage never hurts, though most lots sit fine at room temperature provided humidity stays below 60%. Repeated opening and closing of bulk bottles drags air and water vapor into the mix, so best practice splits larger deliveries into smaller, single-use bottles soon after receipt. Those handling heavy drums watch out for static discharge when scooping powder; one rogue spark might send dust billowing, so earth-grounding stations and antistatic mats come standard in up-to-date chemical stores.
During shipping, solid product avoids most hazards linked to flammable or volatile organics, yet customs treats all unfamiliar white powders with suspicion. Double-bagged liner packaging, clear batch numbers, and bilingual labeling make sure it passes inspection with limited delay. Broken containers or poorly sealed shipments, on the other hand, invite headaches: spilled product, lost paperwork, and costly holdups at the border. My own worst experience came with a crushed outer drum, where a week’s work turned into a pagelong incident report, underscoring why packing and labeling matter as much as the fine structure confirmed by NMR. Importers and distributors keep sharp-eyed on the changing lists of controlled substances, as molecular cousins to this compound wind up with tight restrictions for pharma or narcotics compliance reasons.
Those committed to green chemistry carve out opportunities even in the minor chemical intermediates. Switching from open pan drying to closed-system vacuum drying cuts both waste and exposure risks for workers. Automated powder handling and dispensing systems step beyond what hands and scoops can do for reducing dust and loss — a lesson learned through repeated exposure and cleanup drills. Many labs have started using barcoded tracking systems for every batch and disposal process, knocking out sources of confusion and lost record-keeping. On the supplier side, moving toward recycled or more robust packaging materials makes sense, both for financial savings and for cutting out unnecessary landfill.
Factoring in the broader context, tighter integration between research labs and regulatory teams shortens the gap between innovation and compliance. As more specialty chemicals shift from batch synthesis to continuous flow systems, waste goes down and reproducibility goes up. The challenge, as always, remains to balance cost, safety, and scalability — turning high-quality research chemicals like (±)-1-((2-(3,4-Dimethoxyphenyl)ethyl)amino)-3-(3-methylphenoxy)-2-propanol Hydrochloride from elusive powders to reliable, tracked, and safe raw materials. Thinking forward, researchers and producers both share a stake in the outcomes, each aimed at pushing progress while keeping people and the planet in mind.
Providing high-quality chemical products and logistics solutions for global trade partners.
