Chemical Name: Vanilline Propylene Glycol Acetal
Synonyms: 2-(4-Hydroxy-3-methoxybenzylidene)-1,3-propanediol acetal
CAS Number: 104-46-1
Molecular Formula: C12H16O4
Molecular Weight: 224.25 g/mol
Recommended Use: Flavor and fragrance ingredient in food, cosmetics, personal care, household products
Supplier: Refer to manufacturer or distributor contact details on packaging
Emergency Telephone: Refer to local regulatory requirement or packaging for emergency contact
Product Description: Colorless to pale yellow liquid, sweet characteristic vanilla-like odor, slightly viscous texture
GHS Classification: Eye irritation (Category 2A), Skin sensitization (Category 1B)
Signal Word: Warning
Hazard Statements: Causes serious eye irritation, may cause allergic skin reaction
Precautionary Statements: Avoid contact with eyes/skin, wear protective gloves/eye protection, wash thoroughly after handling
Appearance: Pale yellow liquid
Odor: Sweet vanilla
Route of Entry: Inhalation, skin contact, eye contact, ingestion
Acute Effects: Eye/skin irritation, respiratory tract sensations upon vapor exposure
Chronic Effects: Possible skin sensitization with repeated/prolonged contact
Environmental Hazards: May cause damage in aquatic environments due to high chemical oxygen demand
Main Component: Vanilline Propylene Glycol Acetal, >90% by weight
Impurities: Propylene glycol, vanillin, aromatic byproducts (<1% each, may vary by batch)
CAS Registry Number: 104-46-1 (main ingredient)
Hazardous Components: Vanilline Propylene Glycol Acetal, GHS Category Eye irritant, Sensitizer
Other Additives: None intentionally added
Ingredient Transparency: Contains no substances classified as carcinogenic, mutagenic or reproductive toxins at relevant concentrations
Inhalation: Move person into fresh air, keep comfortable for breathing, seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, wash skin thoroughly with mild soap and water, seek medical advice if irritation develops
Eye Contact: Rinse immediately with water for several minutes, remove contact lenses, continue rinsing, seek ophthalmological evaluation if irritation persists
Ingestion: Rinse mouth, drink water to dilute, do not induce vomiting, get medical attention if feeling unwell
Personal Protective Equipment for First Responders: Chemical-resistant gloves, eye protection
Notes for Doctor: Treat symptomatically, no known antidote
Special Medical Procedures: None recommended under normal use conditions
Extinguishing Media: Carbon dioxide, dry chemical powder, alcohol-resistant foam, water spray
Fire Hazards: Combustible liquid, emits toxic fumes of carbon oxides under fire conditions
Special Protective Equipment: Firefighters should wear self-contained breathing apparatus, full protective gear
Explosion Hazard: Low vapor pressure under ambient conditions, but vapor accumulation indoors may present ignition risk
Unusual Fire/Explosion Hazards: Formation of hazardous decomposition fumes (formaldehyde, carbon monoxide) if heated strongly
Advice for Firefighters: Cool containers with water spray, avoid runoff into water bodies
Personal Precautions: Use personal protective equipment, avoid inhaling vapors/mists, prevent eye/skin contact
Environmental Precautions: Prevent entry into drains, sewers, waterways
Containment: Absorb spills with non-combustible material (sand, soil, vermiculite), place in labeled container
Cleanup Procedures: Mop area with detergent and water, ventilate area well, dispose of waste according to regulations
Reporting: Notify local authorities if large spill poses environmental risk
Safety Practices: Avoid release to the environment, implement good industrial hygiene measures
Handling: Use only in well-ventilated areas, avoid breathing vapors, wear gloves/eye protection, wash hands after handling
Storage Requirements: Keep in tightly closed original container, protect from light and heat, store away from oxidants, acids, strong bases
Incompatible Materials: Strong oxidizing agents, acids
Specific Practices: Store in designated chemical storage cabinet, segregate from food and drink, label containers
Recommended Packaging: Use corrosion-resistant containers, secondary containment for bulk storage
Occupational Exposure Limit: No established limit for this material; minimize exposure
Engineering Controls: Local exhaust ventilation, process enclosures where feasible
Personal Protection: Chemical-resistant gloves, safety goggles or face shield
Respiratory Protection: Use approved respirator if workplace exposure exceeds applicable limits or produces irritation
Skin Protection: Protective clothing, impervious to chemical
Eye Protection: Splash-proof goggles
Hygiene: Do not eat, drink or smoke near work area, wash exposed skin before breaks and after handling
Environmental Control: Prevent chemical release to stormwater or municipal systems
Appearance: Pale yellow clear liquid
Odor: Vanilla-like, sweet and characteristic
pH: Not available
Melting Point: Not determined (liquid at ambient temperature)
Boiling Point: 265–280°C (estimated)
Flash Point: >100°C (closed cup)
Evaporation Rate: Slow
Flammability: Combustible, not highly flammable
Vapor Pressure: <1 mmHg at 20°C (very low)
Relative Density: 1.14–1.16 g/cm³
Solubility: Soluble in alcohol, slightly soluble in water
Partition Coefficient octanol/water (log Kow): 1.3–1.6 (estimated)
Viscosity: Moderately viscous
Autoignition Temperature: Not determined
Decomposition Temperature: Not available
Chemical Stability: Stable under normal storage and use
Conditions to Avoid: Prolonged exposure to heat, light, open flames
Incompatible Materials: Strong oxidizers, acids
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, possible aldehydes
Polymerization Hazard: No known hazardous polymerization
Reactivity Profile: Low reactivity in intended applications, may react with strong acids/bases
Acute Toxicity: Oral LD50 (rat): >2000 mg/kg
Skin Corrosion/Irritation: May cause moderate to severe irritation on prolonged contact
Eye Damage/Irritation: Causes eye irritation based on animal data
Inhalation: Mist or vapor may irritate respiratory tract
Skin Sensitization: May induce allergic reaction in susceptible individuals
Carcinogenicity/Mutagenicity: Not listed as carcinogen or mutagen by IARC, NTP, OSHA
Chronic Effects: No confirmed chronic health effects under normal occupational exposure
Other Health Hazards: Contains no ingredients known to cause reproductive toxicity at relevant concentrations
Ecotoxicity: Low to moderate hazard for aquatic life, no specific LC50 data available
Persistence and Degradability: Expected to undergo biodegradation, breakdown may be slow
Bioaccumulation Potential: Low based on estimated log Kow
Mobility in Soil: Low volatility, limited mobility
Aquatic Release Effects: High concentrations may cause oxygen depletion
Other Information: Not expected to persist in environment when used as directed
Waste Treatment Methods: Dispose via licensed hazardous waste contractor
Unused Material: Incineration or chemical treatment
Packaging Waste: Triple rinse containers, puncture, then recycle or landfill as per local regulations
Contaminated Absorbent: Treat as hazardous chemical waste
Precautions: Do not discharge into drains, avoid environmental contamination
Legal Compliance: Dispose in accordance with all regional, national and local laws
UN Number: Not classified as dangerous goods by most regulations
UN Proper Shipping Name: Not applicable
Transport Hazard Class: Not regulated
Packing Group: Not assigned
Hazard Labels: Not required for transport
Special Precautions: Avoid extreme temperatures during transport, secure containers against leakage or breakage
Environmental Hazards: Not a marine pollutant
OSHA: Not hazardous under OSHA Hazard Communication Standard
TSCA: Listed
REACH: Exempted or registered for intended uses
GHS Label Elements: Eye irritant, Skin Sensitizer
SARA Title III: Not subject to reporting
Chemical Safety Assessment: Not required for non-industrial user concentrations
WHMIS: Classified as D2B (Toxic material causing other effects)
Specific State/Country Information: Ingredient may be listed under regional chemical inventories or restrictions, refer to local regulations for full details
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