Product Name: Tripropyleneglycol monomethyl ether
Synonyms: 1-methoxy-2,6,10-trioxaundecane; PPG3ME
Chemical Family: Glycol ether
Recommended Use: Solvent in paints, coatings, cleaning agents
Supplier: Contact manufacturer for current supply chain details
CAS Number: 25498-49-1
Emergency Telephone: Refer to emergency contact number on shipping documents
GHS Classification: Eye irritation (Category 2A), Specific target organ toxicity
Hazard Statements: Causes serious eye irritation; May cause respiratory irritation; Harmful if swallowed
Pictograms: Exclamation mark
Signal Word: Warning
Precautionary Statements: Wear protective gloves, eye protection; Avoid breathing vapors; Wash hands thoroughly after handling
Potential Health Effects: Eye and skin contact may cause irritation; Inhalation of vapor can bring dizziness or headaches; Swallowing may cause nausea
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Chemical Name: Tripropyleneglycol monomethyl ether
Common Name: PPG3ME
Concentration: >95% by weight
Impurities: Other glycol ethers (trace), Propylene oxide derivatives
CAS Number: 25498-49-1
Molecular Formula: C10H22O4
Inhalation: Move person to fresh air; keep comfortable for breathing; seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing; rinse skin with soap and water; seek medical help for persistent irritation
Eye Contact: Rinse cautiously with water for at least 15 minutes; remove contact lenses if present and easy to do; get prompt medical advice
Ingestion: Rinse mouth; do not induce vomiting; get immediate medical attention
Most Important Symptoms: Irritation, redness, discomfort, dizziness
Note to Physicians: Provide symptomatic and supportive treatment as required
Suitable Extinguishing Media: Water spray, dry chemical, foam, carbon dioxide
Unsuitable Extinguishing Media: Direct water jet can spread fire
Special Hazards: Vapors can form explosive mixtures with air; combustion releases carbon monoxide, carbon dioxide
Protective Equipment: Firefighters should use self-contained breathing apparatus and protective clothing
Fire Fighting Procedures: Cool fire area with water to prevent reignition; Contain run-off to prevent environmental contamination
Personal Precautions: Evacuate personnel from affected area; ensure good ventilation; avoid breathing vapors
Protective Equipment: Wear chemical-resistant gloves, safety goggles, suitable protective clothing
Methods for Containment: Contain spillage with non-combustible absorbent materials (sand, earth, vermiculite)
Methods for Cleaning Up: Sweep up and place in suitable sealed containers; wash area with water; avoid release to the environment
Environmental Precautions: Prevent entry to drains, water courses, or soil; notify authorities if large spills cannot be contained
Safe Handling: Use only in well-ventilated areas; avoid inhalation of vapors and skin or eye contact; do not eat, drink or smoke during use
Handling Procedures: Transfer and handle with equipment rated for flammable or combustible liquids
Storage Requirements: Store in tightly sealed containers in cool, dry, well-ventilated areas; keep away from heat sources and incompatible materials
Incompatible Materials: Strong oxidizing agents, strong acids, strong bases
Special Considerations: Keep containers tightly closed and properly labeled; check for leaks regularly
Occupational Exposure Limits: No specific OSHA or ACGIH exposure limits established; maintain levels as low as achievable
Engineering Controls: Local exhaust and general ventilation required to control vapor concentrations
Personal Protective Equipment:
Respiratory—approved organic vapor mask;
Eyes—chemical tight safety goggles;
Skin—impervious gloves, clothing covering arms and legs
Hygiene Measures: Wash hands before breaks and at the end of work; remove contaminated clothing and wash before reuse
Appearance: Clear, colorless to pale yellow liquid
Odor: Mild ether-like odor
pH: Not applicable
Melting/Freezing Point: -70°C
Boiling Point: 250-275°C
Flash Point: 108°C (closed cup)
Evaporation Rate: Slower than ether
Flammability: Not classified as highly flammable, but can ignite
Upper/Lower Flammability: 0.9% (LFL), 7.5% (UFL) by volume
Vapor Pressure: 0.06 mmHg at 20°C
Vapor Density: 5 (air = 1)
Relative Density: 0.96–0.98 (water = 1)
Solubility: Soluble in water and organic solvents
Auto-ignition Temperature: 320°C
Decomposition Temperature: Data not available
Viscosity: 8–15 mPa·s at 25°C
Chemical Stability: Stable under normal storage and handling conditions
Hazardous Reactions: Reacts with strong oxidizers; may form peroxides under air and light exposure
Conditions to Avoid: Heat, sparks, flames, freezing; avoid contact with moisture
Incompatible Materials: Strong acids, bases, oxidizing substances
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, and other toxic gases may form under fire conditions
Acute Toxicity: Oral LD50 (rat) >4000 mg/kg; Dermal LD50 (rabbit) >2000 mg/kg
Inhalation: May cause respiratory irritation, dizziness, drowsiness at high concentrations
Skin Corrosion/Irritation: Prolonged or repeated contact can irritate
Serious Eye Damage: Causes moderate to severe eye irritation on contact
Skin Sensitization: Not known to be a skin sensitizer
Chronic Effects: Prolonged exposure may affect the central nervous system, liver, or kidneys in rare cases
Carcinogenicity: Not listed by IARC, NTP, OSHA
Reproductive Toxicity: No clear evidence from animal studies of reproductive harm
Other Effects: Repeated high exposures can aggravate preexisting conditions in sensitive organs
Ecotoxicity: Low acute toxicity to fish (LC50 >100 mg/L for 96 hr in aquatic species); Low toxicity to aquatic invertebrates and algae
Persistence and Degradability: Readily biodegradable in water and soil; significant breakdown in the environment
Bioaccumulative Potential: Low bioaccumulation expected; partition coefficient (log Kow) 0.56
Mobility in Soil: High mobility due to water solubility
Other Adverse Effects: Large spills may damage aquatic environments by oxygen depletion; avoid uncontrolled releases
Waste Treatment Methods: Dispose through certified waste contractor or at an authorized hazardous waste facility; always follow local and national regulations
Container Disposal: Empty containers may contain residues; do not reuse; triple rinse and puncture before disposal
Disposal Restrictions: Do not release into drains, surface, or ground water; do not incinerate closed containers
Recommended Disposal: Incinerate or landfill in accordance with government and environmental guidance
UN Number: Not regulated for most transport modes
UN Proper Shipping Name: Not classified as a dangerous good by DOT, IMDG, or IATA
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Marine Pollutant: Not a marine pollutant by criteria
Special Precautions: Observe standard transport regulations; avoid excessive heat, packaging damage, or moisture
Safety, Health and Environment Regulations: Covered by TSCA (US inventory), REACH (EU registration), Canadian DSL
Label Elements: Complies with GHS/CLP requirements for chemical labeling
SARA Title III (Sections 311/312): Classified as an immediate (acute) health hazard
SARA Title III (Section 313): Not subject to reporting
California Proposition 65: Not listed
Other International Regulations: Listed in EINECS and ENCS chemical registries; consult local guidelines for workplace exposure and chemical usage
Workplace Labeling: Ensure compliant labeling at all container stages; information available through Safety Data Sheet repository
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