Product Name: Trimeprazine Tartrate
Chemical Name: 10-(3-dimethylaminopropyl)phenothiazine tartrate
Common Synonyms: Alimemazine tartrate, Vallergan
Recommended Use: Pharmaceutical active, antihistaminic, sedative
Supplier: Pharmaceutical manufacturer
CAS Number: 4136-97-2
Contact Details: Provided by supplier, includes emergency telephone number
Formula: C18H22N2S · C4H6O6
Molecular Weight: 460.56 g/mol
UN Number: Not classified
GHS Classification: Acute toxicity (Oral, Category 3); Skin irritation (Category 2); Serious eye irritation (Category 2A)
Signal Word: Danger
Hazard Statements: Harmful if swallowed; Causes skin irritation; Causes serious eye irritation
Precautionary Statements: Wash exposed skin thoroughly after handling; Avoid breathing dust; Wear protective gloves, protective clothing, eye, and face protection
Pictograms: Exclamation mark symbol
Chemical Identity: Trimeprazine Tartrate
Concentration: 95 – 100%
Impurities: Proprietary pharmaceutical impurities, levels trace under 1%
Other Components: No hazardous components exceeding reportable limits
Inhalation: Move affected individual to fresh air. Support breathing if necessary. Seek medical attention if symptoms persist.
Skin Contact: Rinse gently but thoroughly with soap and water. Remove contaminated clothing. Seek advice if skin response develops.
Eye Contact: Rinse eyes cautiously with water for several minutes; remove contact lenses if present and easy to do; continue rinsing. Consult a healthcare provider if irritation or pain persists.
Ingestion: Do not induce vomiting. Rinse mouth with water. Seek medical care if significant ingestion occurred or symptoms develop.
Most Important Symptoms: May cause drowsiness, gastrointestinal upset, respiratory changes, skin and eye irritation.
Immediate Medical Attention: Physician should monitor for respiratory distress, neurotoxic or allergic reactions. Supportive care recommended.
Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical, foam
Unsuitable Extinguishing Media: Avoid high-pressure water streams that may spread powder
Fire Hazards: Product is not highly flammable, but thermal decomposition may create hazardous fumes, including nitrogen oxides, sulfur oxides, carbon monoxide, carbon dioxide
Protective Equipment for Firefighters: Self-contained breathing apparatus, full protective gear
Explosion Hazards: Not known to form explosive mixtures with air
Personal Precautions: Don protective clothing, gloves, eye and respiratory protection
Environmental Precautions: Prevent powder or solution from entering drains, surface water, or soil
Containment Methods: Scoop up spilled powder/dust with non-sparking tools. Avoid raising dust. Use HEPA vacuum or wet methods for cleanup.
Clean-up Methods: Clean contaminated surfaces with soap and water. Dispose of in accordance with local and national regulations.
Decontamination: Do not touch or walk through spilled material unnecessarily
Handling: Avoid contact with skin, eyes, and clothing. Wash hands thoroughly after handling. Prevent the formation of dust. Work in a well-ventilated area.
Storage Conditions: Keep container tightly sealed in a cool, dry, well-ventilated place, away from direct sunlight and incompatible materials.
Storage Temperature: Store at room temperature, recommended 15–30°C
Incompatible Materials: Strong oxidizing agents, bases
Packaging Materials: Use original container. Ensure containers are clearly labeled.
Exposure Limits: No established occupational exposure limits; handle as hazardous pharmaceutical
Engineering Controls: Work in a chemical fume hood or appropriate exhaust system
Personal Protection: Protective gloves (nitrile or neoprene), lab coat, safety glasses with side shields, suitable respiratory protection if dust is present
Hygiene Measures: Wash hands and face after handling. Do not eat, drink, or smoke during use.
Environmental Controls: Prevent release to the environment. Treat liquid/solid waste as hazardous.
Appearance: White or slightly yellow crystalline powder
Odor: Odorless or faint characteristic odor
pH: Not available (slightly acidic aqueous solution)
Melting Point: 202 – 208°C (decomposes)
Boiling Point: Not established (decomposes before boiling)
Solubility: Freely soluble in water; soluble in ethanol; insoluble in ether and chloroform
Density: Not determined precisely
Partition Coefficient (n-octanol/water): Not available
Vapor Pressure: Negligible
Flash Point: Not relevant due to negligible volatility
Evaporation Rate: Not applicable
Appearance Under Light: May show slight yellowing with prolonged air/light exposure
Autoignition Temperature: Not available
Chemical Stability: Stable under recommended handling and storage conditions; sensitive to moisture and prolonged exposure to air
Possible Hazardous Reactions: May react with oxidizing agents
Incompatible Materials: Strong oxidizers, alkalies
Hazardous Decomposition Products: Nitrogen oxides, sulfur dioxides, carbon monoxide, carbon dioxide
Conditions to Avoid: High temperatures, contact with incompatible materials, exposure to air and moisture
Acute Toxicity: Oral LD50 (rat): 220 mg/kg reported in some studies
Routes of Exposure: Inhalation, skin, eye, ingestion
Health Hazards: May cause drowsiness, sedation, dizziness, anticholinergic effects (dry mouth, blurred vision), skin and eye irritation
Chronic Effects: With repeated or prolonged exposure, possible liver, kidney, and central nervous system effects
Sensitization: May cause allergic reaction in predisposed individuals
Carcinogenicity: Not classified as carcinogenic per IARC, NTP, or OSHA
Mutagenicity: No data supporting mutagenic effects in humans
Reproductive Toxicity: No conclusive animal or human evidence
Other Effects: Large overdoses may lead to profound sedation, hypotension, respiratory depression, convulsions
Target Organs: Liver, kidneys, central nervous system
Ecotoxicity: No official data, avoid environmental release
Aquatic Toxicity: Not tested; anticipated to be harmful to aquatic organisms at moderate to high concentrations
Mobility in Soil: Likely to be mobile in water due to solubility
Persistence and Degradability: Unknown; phenothiazines may be slowly biodegradable
Bioaccumulative Potential: No data
Other Information: Do not allow pharmaceutical chemicals to enter waterways or soil.
Waste Disposal Methods: Dispose according to local, regional, and national regulations. Incineration at an approved facility preferred.
Contaminated Packaging: Dispose of as hazardous waste in accordance with regulatory requirements
Unused Product: Return to supplier or dispose as regulated hazardous waste
Environmental Precautions: Do not discharge to drains, public water, or environment
UN Number: Not regulated for transport
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Special Precautions: Ensure packaging remains intact and secure
DOT, ICAO/IATA, IMDG: Not classified as dangerous good
Additional Transport Requirements: Protect from moisture and high heat during transport
TSCA (US): Not listed for commercial use
OSHA Hazard Communication Standard: Classified as hazardous
EC Inventory: Listed under EINECS
REACH Registration: Pharmaceutical use exemption may apply
DSL (Canada): Not listed
SARA Title III: Not classified under Sections 302, 304, or 313
WHMIS Classification: Pharmaceutical product, exempt under certain regulations
Other Regulatory Information: Handle following national and local pharmaceutical substance regulations; occupational exposure monitoring recommended in healthcare and laboratory settings
Providing high-quality chemical products and logistics solutions for global trade partners.
