Product Name: Trimeprazine hemi-(+)-tartrate
Chemical Formula: C18H22N2S•C4H6O6
CAS Registry Number: 133-78-8
Recommended Use: Pharmaceutical intermediate, veterinary sedative, antihistamine
Manufacturer: Refer to supplier label for actual producer and emergency contact information
Synonyms: Alimemazine tartrate, Trimeprazine tartrate
GHS Classification: Harmful if swallowed, Causes eye irritation, May cause drowsiness or dizziness
Label Elements: Signal Word: Warning; Pictograms: Exclamation mark
Hazard Statements: May be harmful if inhaled or swallowed, May cause irritation to skin, eyes, and respiratory tract
Precautionary Statements: Avoid breathing dust, Wash hands thoroughly after handling, Wear eye/face protection, Use only outdoors or in a well-ventilated area
Health Hazards: Drowsiness, respiratory depression, ataxia, tachycardia
Environmental Hazards: May be toxic to aquatic life with long lasting effects
Chemical Identity: Trimeprazine hemi-(+)-tartrate
Common Name: Alimemazine tartrate
Concentration: 100% (pure compound)
Impurities: Trace inorganic salts or process contaminants (manufacturing-dependent)
Molecular Weight: 492.6 g/mol
Inhalation: Remove individual to fresh air, monitor for respiratory distress, seek medical advice if symptoms persist
Skin Contact: Wash affected area with plenty of soap and water, remove contaminated clothing, consult physician if irritation develops
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing, seek medical assistance
Ingestion: Rinse mouth with water, do not induce vomiting, call physician or poison control center immediately
Most Important Symptoms/Effects: CNS depression, possible allergic reactions, anticholinergic effects such as dry mouth, confusion, blurred vision
Suitable Extinguishing Media: Dry chemical, carbon dioxide, foam, water spray
Unsuitable Media: Direct water jet (may spread material)
Specific Hazards Arising from Chemical: May produce toxic fumes including carbon monoxide, nitrogen oxides, sulfur oxides under fire conditions
Protective Equipment: Wear self-contained breathing apparatus, full protective suit
Special Procedures: Avoid smoke exposure, move containers from fire area, contain run-off to prevent entry into water sources
Personal Precautions: Use personal protective equipment, avoid dust formation, ventilate area well
Environmental Precautions: Prevent entry into watercourses, drains, soil
Cleanup Methods: Sweep up (avoiding dust generation), place in approved container for disposal, wash area with detergent
Disposal: Follow local regulations for pharmaceutical compounds, incineration recommended
Handling: Use with adequate ventilation, avoid contact with eyes, skin, clothing, wash thoroughly after use
Protection: Laboratory coat, gloves, safety glasses
Storage Conditions: Store in a tightly closed container, shielded from direct sunlight, cool and dry place
Incompatible Materials: Strong oxidizers, acids, bases
Hygiene Practices: No eating, drinking, or smoking in handling areas
Exposure Limits: No established occupational exposure limit; always minimize exposure
Engineering Controls: Use fume hood, local exhaust
Respiratory Protection: NIOSH-approved respirator if dust or aerosol forms
Eye/Face Protection: Safety goggles or face shield
Skin Protection: Chemical-resistant gloves and clothing
Workplace Monitoring: Routine monitoring for airborne particulates
Appearance: White or off-white crystalline powder
Odor: Odorless or faint chemical smell
pH: No data for solid; in aqueous solution, slightly acidic
Melting Point: Around 186–189°C
Boiling Point: Decomposes before boiling
Solubility: Freely soluble in water and alcohol
Vapor Pressure: Not applicable
Density: Approx. 1.3 g/cm³ (estimated)
Partition Coefficient: No data available
Flash Point: Not applicable (solid)
Chemical Stability: Stable under recommended storage conditions
Conditions to Avoid: Heat, humidity, open flames, direct sunlight
Reactivity: Reacts with strong oxidizing agents
Decomposition Products: Nitrogen, carbon oxides, sulfur oxides
Hazardous Polymerization: Will not occur
Routes of Exposure: Inhalation, ingestion, skin, and eye contact
Acute Toxicity: LD50 (oral, rat): approx. 220 mg/kg
Chronic Toxicity: Long-term exposure may affect liver and central nervous system
Carcinogenicity: Not listed as a carcinogen by IARC, NTP, OSHA
Reproductive Toxicity: Data is limited; possible effects on fetal development cannot be excluded
Other Effects: May cause hypersensitivity, ataxia, convulsions, dry mucous membranes, tachycardia, hypotension, extrapyramidal symptoms
Aquatic Toxicity: May prove toxic to fish and invertebrates at high concentrations
Persistence and Degradability: Expected to be biodegradable over time
Bioaccumulation Potential: Low potential for bioaccumulation
Mobility in Soil: Moderate mobility due to water solubility
Other Environmental Hazards: Avoid uncontrolled release to the environment; pharmacologically active compounds may affect aquatic organisms
Waste Treatment Methods: Incineration at licensed facility wherever possible
Disposal of Contaminated Packaging: Rinse thoroughly before recycling or disposal, follow local and national regulations
Special Precautions: Do not allow unneutralized material to reach sewage or water systems
Legal Requirements: Dispose of as hazardous chemical waste under RCRA or comparable local regulations
UN Number: Not regulated for transport under ADR/RID/IMDG/IATA
Proper Shipping Name: Not assigned (non-hazardous for transport)
Transport Hazard Classes: None
Packing Group: Not assigned
Special Precautions for Transport: Protect from moisture and rough handling, not to be transported with foodstuff or animal feed
US TSCA: Listed or complies with inventory listing
SARA 313: Not subject to reporting requirements
OSHA: Not classified as hazardous; use prudent practices
EU REACH: Not registered due to pharmaceutical exemption
Other Regulations: Subject to pharmaceutical controls, disposal and use may be restricted under regional or local guidelines, follow specific country and workplace safety laws regarding pharmaceuticals
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