Product Name: Synephrine Tartrate
Chemical Name: 4-[1-Hydroxy-2-(methylamino)ethyl]phenol tartrate
Synonyms: para-Synephrine Tartrate, Oxedrine Tartrate
CAS Number: 5985-28-4
Manufacturer: [Manufacturer details to be provided by supplier]
Recommended Use: Raw material for research, manufacturing, or analytical testing
Emergency Contact: [Contact information to be supplied by distributor]
Product Form: Solid crystalline powder
Classification: Irritant, Harmful if swallowed
GHS Label Elements: Exclamation mark, Health hazard
Signal Word: Warning
Potential Health Effects: May cause moderate eye and skin irritation, respiratory discomfort, and gastrointestinal distress if ingested
Target Organs: Eyes, skin, respiratory tract
Routes of Entry: Ingestion, inhalation, skin and eye contact
Hazard Statements: H302: Harmful if swallowed. H315: Causes skin irritation. H319: Causes serious eye irritation
Precautionary Statements: Wash skin and hands thoroughly after handling; avoid breathing dust; use in well-ventilated areas
Chemical Name: Synephrine Tartrate
Chemical Formula: C13H21NO6
Molecular Weight: 287.31 g/mol
Purity: >98%
Impurities: Typically present at less than 1% total
Other Ingredients: No other significant constituents
Eyes: Rinse cautiously with water for at least 15 minutes, hold eyelids open; remove contact lenses if present and easy to do
Skin: Wash with soap and plenty of water, remove contaminated clothing; seek medical attention for persistent irritation
Inhalation: Remove victim to fresh air; keep at rest in a position comfortable for breathing; seek medical advice if symptoms persist
Ingestion: Rinse mouth with water, do not induce vomiting unless instructed by medical personnel; seek immediate medical attention
Most Important Symptoms: Eye redness, burning sensation, coughing, nausea
Notes for Physician: Treat symptomatically and supportively
Suitable Extinguishing Media: Water spray, foam, dry powder, carbon dioxide
Unsuitable Extinguishing Media: Full water jet (may spread product)
Specific Hazards: May release toxic fumes of nitrogen oxides, carbon monoxide, carbon dioxide when heated
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Special Precautions: Cool exposed containers with water spray to prevent pressure build-up
Personal Precautions: Avoid dust generation; use personal protective equipment; ventilate affected area
Environmental Precautions: Prevent further leakage or spillage; keep material out of watercourses and drains
Methods for Cleaning Up: Sweep or absorb material with inert, non-flammable absorbent; transfer to suitable container for disposal; clean surfaces with water after collection
Additional Advice: Dispose according to federal, state, and local regulations; notify authorities if a large spill occurs
Handling: Prevent contact with skin and eyes; avoid inhalation of dust; use in well-ventilated conditions; wear suitable protective clothing, gloves, and eye/face protection; keep away from food, drink, and animal feed
Storage: Keep in tightly sealed original container; store in a cool, dry, and well-ventilated area away from incompatible substances (strong acids, bases, oxidizers); protect from moisture and direct sunlight
Incompatibilities: Do not store with strong oxidizing agents or bases
Storage Temperature: Recommended at 2–8°C for best stability
Exposure Limits: No occupational exposure limits specified by OSHA, NIOSH, or ACGIH
Engineering Controls: Use local exhaust ventilation or process enclosures; maintain appropriate air exchange
Respiratory Protection: NIOSH-approved respirator for dust if ventilation is inadequate
Eye Protection: Safety goggles or face shield
Skin Protection: Wear lab coat, protective gloves (nitrile, latex), and appropriate foot covering
Hygiene Measures: Wash hands immediately after handling; do not eat, drink, or smoke during use
Appearance: White to off-white crystalline powder
Odor: Odorless or faint
Odor Threshold: Not applicable
pH: 4.0–6.0 (1% solution in water)
Melting Point: 161–163°C
Boiling Point: Data not available
Flash Point: Not applicable
Flammability: Not classified as flammable, may burn with strong heating
Vapor Pressure: Negligible at room temperature
Solubility: Soluble in water, sparingly soluble in ethanol
Density: Approximately 1.36 g/cm3
Partition Coefficient (log Kow): Not determined
Decomposition Temperature: >250°C
Viscosity: Not applicable
Evaporation Rate: Not applicable
Chemical Stability: Stable under recommended storage conditions
Conditions to Avoid: Exposure to excessive heat, moisture, strong sunlight
Incompatible Materials: Strong acids, strong bases, oxidizing agents
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, tarry residues
Possibility of Hazardous Reactions: No dangerous polymerizations reported
Acute Toxicity: Oral LD50 (rat): estimated 250–500 mg/kg
Skin Corrosion/Irritation: May cause moderate irritation on prolonged skin contact
Serious Eye Damage/Irritation: Causes eye irritation, redness, discomfort
Respiratory or Skin Sensitization: No data currently available
Chronic Toxicity: Long-term effects not well described in literature, limited evidence for mutagenicity or carcinogenicity
Symptoms of Overexposure: Nausea, vomiting, headache, dizziness, rapid heartbeat at higher doses
Other Data: No listed effects on reproductive or developmental toxicity
Ecotoxicity: No specific data on aquatic or terrestrial toxicity in available resources; may pose risk to aquatic environments at high concentrations
Biodegradability: Data incomplete, presumed to be readily biodegradable based on structure
Bioaccumulative Potential: No evidence for bioaccumulation in aquatic organisms
Mobility in Soil: Expected to have moderate mobility due to water solubility
Other Adverse Effects: Low likelihood of causing significant ozone depletion, photochemical ozone creation, or global warming; avoid large releases to surface waters and sewers
Disposal Methods: Incineration in an approved facility or landfilling per local regulations; do not incinerate closed containers
Container Disposal: Triple rinse and dispose in accordance with regulatory guidelines
Environmental Precautions: Avoid mass discharge to environment; do not allow into drains or natural waters
Special Instructions: Consult specialist waste disposal companies where local rules require
UN Number: Not classified as a dangerous good by UN, nor by IATA or IMO
Proper Shipping Name: Not regulated for transport
Hazard Class: Not applicable
Packing Group: Not applicable
Marine Pollutant: No
Special Precautions: Transport in tightly sealed containers; avoid generating dust during transport; keep separate from incompatible materials
US Regulations: Not listed under SARA Title III or California Proposition 65; not included in DEA controlled substances list
EU Regulations: Not subject to registration under REACH when used as a research chemical; not listed as a substance of very high concern
Labelling Requirements: Label containers with product name, hazard pictograms, and handling instructions
Workplace Safety: Employers must ensure workers are trained on chemical hazards and safe handling practices
International Inventories: Listed or exempted on most country-specific chemical inventories
Other Requirements: Local regulations may require reporting of significant spills or releases; maintain all documentation and records as required by applicable law
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