Material Safety Data Sheet for Synephrine L-tartrate

Identification

Chemical Name: Synephrine L-tartrate
Synonyms: p-Synephrine tartrate, p-Synephrine L-(+)-tartrate
CAS Number: 5985-28-4
Molecular Formula: C9H13NO2 • C4H6O6
Recommended Use: Chemical additive, laboratory reagent
Manufacturer Contact: Provided per supplier
Emergency Phone: Consult local regulations or package insert
Product Code: As supplied

Hazard Identification

Classification: Harmful if swallowed, mild irritant to skin and eyes
Signal Word: Warning
GHS Pictograms: Exclamation mark
Hazard Statements: May cause drowsiness or dizziness. Ingestion can lead to gastrointestinal upset. May cause mild irritation to respiratory tract if dust is inhaled
Precautionary Statements: Avoid breathing dust. Use only outdoors or in well-ventilated areas. Wash hands after handling. If in eyes or on skin: rinse cautiously with water for several minutes
Potential Health Effects: Eye irritation, skin discomfort, respiratory irritation, gastrointestinal disturbance due to ingestion

Composition / Information on Ingredients

Component: Synephrine L-tartrate
Chemical Formula: C13H19NO8
Purity: >98%
CAS No: 5985-28-4
Impurities: Not anticipated at hazardous levels
Additives: None reported

First Aid Measures

Inhalation: Move affected person to fresh air. Seek medical advice if symptoms persist. Remove from exposure, loosen clothing at neck and waist.
Skin Contact: Wash with plenty of soap and water. Remove contaminated clothing and shoes. Contact physician if irritation develops.
Eye Contact: Rinse with water for several minutes, keeping eyelids open. Seek ophthalmic advice if irritation persists.
Ingestion: Rinse mouth, do not induce vomiting. Drink water if conscious. Obtain medical attention if feeling unwell or if large amounts consumed
Acute Effects: Mild irritation or discomfort
Note to Physician: Treat supportively. Monitor for allergic response.

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical, carbon dioxide
Unsuitable Extinguishing Media: High-pressure water streams may scatter chemical
Hazardous Combustion Products: Carbon dioxide, carbon monoxide, nitrogen oxides, possible irritant smoke
Special Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Unusual Fire Hazards: Dust may form explosive mixture in air, though generally low risk
Firefighting Instructions: Keep containers cool with water spray to prevent pressure build-up

Accidental Release Measures

Personal Precautions: Wear gloves, protective eyewear, dust mask if necessary. Avoid breathing dust. Keep unprotected persons away.
Environmental Precautions: Avoid entering sewers, water sources, or soil. Prevent run-off into drains.
Methods for Cleaning Up: Sweep up and collect spillage into labeled containers. Dampen with water to avoid dust formation. Waste disposal according to local authority requirements.
Decontamination Procedures: Wash area with soap and water. Ventilate the area after cleanup.
Emergency Procedures: Refer to Section 8 for protective equipment.

Handling and Storage

Precautions for Safe Handling: Avoid creating dust. Handle with care, using appropriate PPE. Do not eat, drink, or smoke when processing. Use in well-ventilated places.
Storage Conditions: Store in tightly closed containers in cool, dry, and well-ventilated area away from sunlight and incompatible materials.
Material Incompatibilities: Strong oxidizing agents, acids, bases.
Specific Procedures: Label containers clearly. Practice good industrial hygiene and safety procedures.

Exposure Controls and Personal Protection

Occupational Exposure Limits: None established for Synephrine L-tartrate
Engineering Controls: Use local exhaust ventilation or general room ventilation
Respiratory Protection: Dust mask or NIOSH-approved respirator if ventilation is insufficient
Skin Protection: Chemical-resistant gloves. Long-sleeved lab coat recommended.
Eye Protection: Safety goggles or face shield
Hygiene Measures: Wash hands thoroughly after handling. Remove and wash contaminated clothing before reuse.

Physical and Chemical Properties

Appearance: White or off-white crystalline powder
Odor: Faint, characteristic odor
Odor Threshold: Not determined
pH: 3.0–5.0 (1% solution in water)
Melting Point: 80–95°C (decomposition possible on heating)
Boiling Point: Not determined
Flash Point: Not highly flammable
Evaporation Rate: Not applicable (solid material)
Flammability: Material not classified as flammable
Explosion Limits: Not established
Vapor Pressure: Not applicable
Vapor Density: Not applicable
Relative Density: 1.5–1.6 (estimated)
Solubility: Soluble in water, sparingly soluble in ethanol
Partition Coefficient: Not determined
Decomposition Temperature: Not specified
Viscosity: Not applicable

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Reactivity: Not highly reactive under normal handling
Conditions to Avoid: Excessive heat, humidity, open flames, dust accumulation
Incompatible Materials: Strong oxidizers, acids, strong bases
Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides
Hazardous Polymerization: Does not occur

Toxicological Information

Likely Routes of Exposure: Skin, eyes, inhalation, ingestion
Acute Toxicity: Oral LD50 in rats estimated >2000 mg/kg (low acute toxicity)
Skin Corrosion/Irritation: May cause mild irritation in sensitive persons.
Serious Eye Damage/Irritation: Mild to moderate transient irritation possible.
Respiratory or Skin Sensitization: Not expected based on available data.
Carcinogenicity: Not classified as carcinogen by IARC, NTP, OSHA
Mutagenicity: No data indicating mutagenic effects
Reproductive Toxicity: No conclusive evidence of toxicity to reproduction
Chronic Effects: Not known to produce chronic health conditions.

Ecological Information

Aquatic Toxicity: No reported direct toxicity to aquatic organisms at low concentrations
Persistence and Degradability: Expected to be biodegradable
Bioaccumulation Potential: Low, unlikely to partition into fat
Soil Mobility: May move through soil if released, but likely to degrade
Additional Information: Avoid environmental discharge, follow good chemical stewardship practices

Disposal Considerations

Waste Classification: Non-hazardous chemical waste under most regulations
Methods of Disposal: Dispose of via licensed chemical waste contractor. Do not pour into drains or natural bodies of water. Incineration in accordance with local, regional, and national regulations recommended.
Container Disposal: Triple-rinse and dispose of empty containers according to local guidelines
Additional Advice: Follow all state, federal, and local environmental regulations.

Transport Information

UN Number: Not regulated under UN transport rules
UN Proper Shipping Name: Not classified as dangerous goods
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Labels: No special labeling required
Special Precautions: Protect from physical damage and climatic extremes.

Regulatory Information

Inventory Status: Listed in country or regional chemical inventories (TSCA, EINECS/ELINCS, DSL, AICS as appropriate)
USA Federal Regulation: Not subject to SARA Title III, not listed as toxic chemical
California Prop. 65: Not listed
EU Regulation: Not classified as dangerous according to Regulation (EC) No 1272/2008 (CLP)
Workplace Classification: General chemical, not considered hazardous for routine handling with normal precautions
Other Relevant Regulation: Adhere to all local regulations for procurement, storage, handling, and disposal.