Product Name: Sodium stibogluconate
Chemical Formula: C12H21NaO16Sb
CAS Number: 16037-91-5
Intended Use: Pharmaceutical applications, mainly in treatment of leishmaniasis
Synonyms: Sodium antimony gluconate, Pentostam
Supplier: Pharmaceutical manufacturers, authorized distributors
Emergency Contact: Use national poison control center or local emergency medical services
Classification: Harmful if swallowed, severe eye irritant, skin sensitizer
Acute Health Effects: Headache, nausea, vomiting, cardiac disturbances, injection site reactions
Chronic Effects: Prolonged exposure risks organ damage to liver, kidneys, heart
Signal Word: Warning
Routes of Exposure: Ingestion, inhalation, skin and eye contact
Hazard Statements: Causes skin irritation, serious eye irritation, may cause respiratory irritation
Pictograms: Exclamation mark, health hazard, environment
Chemical Name: Sodium stibogluconate
Purity: Usually above 90% by weight
Active Ingredient: Antimonial compound, sodium stibogluconate
Other Components: Residual water, minor organic impurities
Eye Contact: Rinse cautiously with water for at least 15 minutes, remove contact lenses, continue rinsing, seek medical help
Skin Contact: Wash exposed skin thoroughly with soap and water, remove contaminated clothing, seek medical advice if irritation appears
Inhalation: Move person to fresh air, keep comfortable, support breathing if trouble starts, get medical attention
Ingestion: Rinse mouth, never give anything by mouth to an unconscious person, call poison control, seek immediate medical care
Medical Attention: Immediate for all significant exposures, monitor for signs of antimony toxicity
Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide
Specific Hazards: Fire creates toxic fumes of antimony oxides and sodium compounds
Protective Equipment: Self-contained breathing apparatus, full protective gear
Advice for Firefighters: Move containers from fire area if safe, avoid inhalation of combustion fumes
Personal Precautions: Keep unprotected personnel away, provide adequate ventilation, wear protective equipment
Spill Response: Absorb with inert material such as sand or vermiculite, scoop into labeled containers, seal for waste disposal
Environmental Precautions: Prevent material entering waterways, drains, or soil
Clean-Up Procedures: Detergent and water for area decontamination, dispose waste safely
Handling: Use in a chemical fume hood or controlled setting, avoid inhaling dust or vapors, prevent skin and eye contact, keep containers tightly closed
Storage: Store in a cool, dry, well-ventilated place away from incompatible materials, protect from light and moisture, secure storage area to prevent unauthorized access
Incompatibilities: Strong oxidizers, reducing agents, acids, bases, metals
Engineering Controls: Use local exhaust ventilation, safety shower, and eye wash stations
Personal Protection: Chemical-resistant gloves, protective clothing, tightly fitting safety goggles, approved respirator for dust or vapor risk
Hygiene Measures: Wash hands after handling, avoid eating or drinking in work areas
Appearance: White to off-white, hygroscopic powder
Odor: Odorless
pH (1% solution): Neutral to slightly alkaline
Melting Point: Decomposes before melting
Boiling Point: Not applicable
Solubility: Freely soluble in water, insoluble in organic solvents
Vapor Pressure: Negligible
Relative Density: 1.8 – 2.2 g/cm³
Partition Coefficient: Not determined
Evaporation Rate: Not applicable
Chemical Stability: Stable under recommended storage and handling conditions
Thermal Decomposition: Gives off toxic antimony oxides and sodium fumes
Reactivity: May react with acids and strong oxidizers
Hazardous Reactions: Risk of explosive or exothermic reactions with incompatible substances
Acute Toxicity: Ingestion produces abdominal pain, vomiting, heart rhythm changes, death at high doses
Inhalation Risk: Respiratory tract irritation, headache
Skin Contact: Irritation, possible allergic reaction
Eye Contact: Causes severe irritation, tearing, redness
Delayed Effects: Damage to heart, liver, kidneys on repeated or high-dose exposure
Carcinogenicity: No definitive evidence in humans, animal studies inconclusive
Mutagenicity: Not adequately tested, concern persists for persistent compounds
Aquatic Toxicity: Harmful to aquatic organisms, potential bioaccumulation in water systems
Soil Mobility: High solubility raises risk of groundwater contamination
Persistence and Degradability: Slow to degrade, strong environmental persistence
Ecotoxicity Concerns: Disrupts ecosystem balance at low concentrations
Disposal Impact: Improper disposal risks long-term environmental damage
Waste Treatment: Collect and send to specialized chemical waste facility
Contaminated Packaging: Treat empty containers as hazardous, follow all local regulations
Precautions: Do not release into environment, handle materials with dedicated tools and PPE
Regulatory Reference: Comply with chemical waste disposal law and environmental protection guidelines
UN Number: 3264
Proper Shipping Name: Corrosive liquid, acidic, organic, n.o.s. (Contains antimony compound)
Transport Hazard Class: 8
Packing Group: III
Marine Pollutant: Yes
Special Precautions: Secure packaging, declaration of dangerous goods, inform transport personnel of toxicity and spill measures
Labeling: Requires hazard pictograms and warning statements under chemical safety law
Chemical Inventory Status: Listed in national and international chemical inventories
Occupational Exposure Limits: Recommended: Antimony compounds TLV 0.5 mg/m³
Pharmaceutical Regulation: Controlled substance, prescription-only for pharmaceutical use
Environmental Restrictions: Discharge and emissions strictly limited by environmental law
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