Product Name: Sodium antimony gluconate
Synonyms: Sodium stibogluconate
Chemical Formula: C12H22O23Sb2Na
Recommended Use: Pharmaceutical intermediate, treatment of leishmaniasis
Manufacturer: Consult product packaging for manufacturer details
Contact Information: Emergency telephone numbers for toxicological emergency
CAS Number: 15451-89-9
EC Number: 239-446-7
Intended Users: Laboratory and clinical professionals
Product Description: Odorless white powder, soluble in water, stability relies on dry and dark storage
GHS Classification: Acute Toxicity - Oral (Category 3), Skin Sensitization (Category 1), Eye Irritation (Category 2A)
Label Elements: Skull and crossbones, exclamation mark
Hazard Statements: Harmful if swallowed, may cause allergic skin reactions, causes eye irritation
Signal Word: Danger
Precautionary Statements: Avoid inhalation, avoid ingestion, wear protective gloves, rinse eyes if contact occurs
Potential Health Effects: Shortness of breath, headache, nausea, skin rash, risk of long-term organ damage after repeated exposure
Symptoms of Exposure: Nausea, abdominal pain, dizziness, allergic manifestations on skin or respiratory tract
Chemical Name: Sodium antimony gluconate
Concentration: 100% (pure substance)
Impurities: May contain trace levels of sodium chloride or related sugars, considered negligible for hazard assessment
Molecular Weight: 692.84 g/mol
Antimony Content: Specific to batch analysis, relevant for toxicological risk
Inhalation: Move person to fresh air, seek medical support if symptoms persist or breathing is difficult, avoid self-exposure
Skin Contact: Remove contaminated clothing, rinse under running water at least 15 minutes, apply soap gently, get medical help for persistent skin effects
Eye Contact: Flush thoroughly with water for 15 minutes, keeping eyelids open, remove contact lenses if present and easy, seek urgent ophthalmic assessment
Ingestion: Rinse mouth with water, never induce vomiting without medical direction, call a poison center immediately
Most Important Symptom/Effect: Nausea, vomiting, muscle pain, respiratory distress, risk of shock in severe exposure
Advice for Physician: Monitor electrolyte balance and renal function, supportive care, consider chelation in significant poisoning
Suitable Extinguishing Media: Water spray, dry chemical powder, carbon dioxide, alcohol-resistant foam
Unsuitable Extinguishing Media: Direct water jet (spatter risk)
Protective Equipment: Full protective suit, self-contained breathing apparatus to avoid toxic decomposition fumes
Fire Hazards: Antimony oxides, sodium oxides, carbon oxides may form on thermal decomposition
Special Precautions: Keep containers cool, prevent runoff into drains, move containers from fire area if safe to do so
Personal Precautions: Use respiratory protection, prevent contact with skin and eyes, wear gloves and eye protection
Spill Response: Collect spillage using non-sparking tools, avoid generation of dust, sweep gently
Cleaning Method: Wipe area with damp material, place residue in a chemical waste container
Environmental Protection: Prevent material from entering sewers or surface water, inform authorities if substantial release occurs
Disposal of Spill: See Disposal Considerations section for approved methods
Safe Handling Practices: Minimize airborne dust, avoid inhalation or ingestion, employ fume hood for weighing or transferring, wash hands after use
Storage Conditions: Store in tightly sealed container, keep in cool dry area, protect from light and moisture
Incompatibles: Strong oxidizing agents, acids, bases—reactivity hazard possible
General Hygiene: Food, beverages, and feed kept away from working area, do not eat or smoke in relevant zones
OSHA/PEL (Antimony): 0.5 mg/m3 (TWA)
Engineering Controls: Enclosed processes, local exhaust ventilation
Personal Respiratory Protection: NIOSH/MSHA-approved respirator for powder handling
Skin Protection: Chemical-resistant gloves, laboratory coat, closed footwear
Eye Protection: Chemical safety goggles
Other Protective Measures: Emergency shower and eyewash stations in the immediate working area
Appearance: White crystalline powder
Odor: Odorless
pH (1% solution): 6.0–8.5
Melting Point: Not available
Boiling Point: Not determined
Solubility: Freely soluble in water, practically insoluble in organic solvents
Vapor Pressure: Negligible at ambient conditions
Density: Approx. 2.5 g/cm3
Volatility: Non-volatile
Chemical Stability: Stable under recommended storage conditions
Possibility of Hazardous Reactions: Reacts with strong oxidizers, risk of toxic fumes
Hazardous Decomposition Products: Toxic antimony oxides, carbon oxides, sodium oxides
Incompatible Materials: Strong acids and bases, oxidizers
Conditions to Avoid: Exposure to moisture, light, excessive heat
Routes of Exposure: Inhalation, ingestion, skin contact, eye contact
Acute Effects: Nausea, vomiting, diarrhea, headache, respiratory distress
Chronic Effects: Liver and kidney injury, skin sensitization, anemia, possible carcinogenicity upon prolonged exposure to antimony compounds
LD50 (Oral, rat): ~ 115 mg/kg (based on similar substances)
Sensitization: May cause delayed dermal reactions
Carcinogenicity: Antimony listed by IARC as Group 2B (possibly carcinogenic to humans), limited evidence
Aquatic Toxicity: Harmful to aquatic organisms, risk of long-term adverse effects in aquatic environment
Persistence and Degradability: Not readily biodegradable, bioaccumulation potential exists due to antimony
Mobility in Soil: Potential for leaching in sandy soils
Other Adverse Effects: Toxicity to soil microorganisms, may impact invertebrate survival and plant growth under high exposure
Waste Treatment Methods: Dispose by authorized hazardous waste handler, incinerate under controlled conditions if possible
Container Disposal: Triple rinse and puncture, do not reuse containers for other purposes
Legal Requirements: Follow local, regional, national, and international regulations for antimony-containing compounds
Do Not: Discharge into waterways, unlined landfills, or sewer systems
UN Number: 3077
UN Proper Shipping Name: Environmentally hazardous substance, solid, n.o.s. (contains antimony compound)
Transport Hazard Class: 9
Packing Group: III
Label: Miscellaneous dangerous materials
Marine Pollutant: Yes
Special Precautions for User: Protect containers from physical damage, avoid accidental release during transit
Inventory Listings: TSCA (USA), DSL (Canada), EINECS (EU)
Workplace Controls: OSHA, ACGIH, NIOSH, European workplace directives
Restricted Components: Subject to restrictions for pharmaceutical use in many countries
Other Regulations: SARA Title III, RoHS (EU), REACH, state and national chemical safety laws
Labeling Requirements: Conforms to GHS and applicable local chemical hazard communication standards