MSDS for Serinol (2-amino-1,3-propanediol)

Identification

Product Name: Serinol
Chemical Formula: C3H9NO2
CAS Number: 534-03-2
Synonyms: 2-Amino-1,3-propanediol, 1,3-Propanediol, 2-amino-, Propanolamine-1,3
Recommended Use: Intermediate for pharmaceuticals, surfactants, and other organic syntheses
Supplier Name: Please refer to your distributor or supplier
Contact Information: Refer to product label or purchasing documents for updated contact channels in case of emergency.

Hazard Identification

GHS Classification: Skin Irritation Category 2, Eye Irritation Category 2A
Signal Word: Warning
Hazard Statements: Causes skin irritation, causes serious eye irritation
Precautionary Statements: Wear protective gloves, eye protection, face protection; wash hands thoroughly after handling; avoid breathing dust or vapors
Pictograms: Exclamation mark
Other Hazards: Not classified as flammable, not considered a carcinogen by OSHA, NTP, IARC.

Composition / Information on Ingredients

Chemical Name: 2-Amino-1,3-propanediol
Concentration: ≥ 99%
CAS Number: 534-03-2
Impurities: Trace amounts of organics or water (typically less than 0.5% by weight)
Stabilizers or Additives: None commonly listed in commercial preparations.

First Aid Measures

Inhalation: Move to fresh air, keep at rest, seek medical attention if symptoms develop
Skin Contact: Remove contaminated clothing, wash affected area with plenty of soap and water, seek medical advice if irritation persists
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing, seek medical evaluation
Ingestion: Rinse mouth with water, do not induce vomiting, seek immediate medical attention
Most Important Symptoms/Effects: Redness, pain, irritation to eyes or skin, discomfort to upper respiratory tract if inhaled
Acute Symptoms: Irritation of eyes, skin, and mucous membranes
Delayed Symptoms: Continued irritation, allergic response in sensitized individuals
Advice for Physicians: Provide symptomatic treatment, consider possibility of chemical exposure.

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry powder, carbon dioxide, foam
Unsuitable Extinguishing Media: Strong water jet (may spread spilled material)
Hazardous Combustion Products: Carbon dioxide, carbon monoxide, nitrogen oxides, under fire conditions
Special Protective Equipment for Fire Fighters: Wear self-contained breathing apparatus and full protective clothing
Specific Hazards: May form combustible dust clouds in air, product itself does not ignite easily
Special Fire Fighting Procedures: Approach fire from upwind, avoid inhaling fumes, remove material from fire area if safe.

Accidental Release Measures

Personal Precautions: Wear suitable protective clothing, including gloves and tightly sealed goggles, avoid bodily contact
Environmental Precautions: Prevent further leakage or spillage if safe, avoid product entering drains, surface water, or ground water
Methods for Clean-Up: Absorb spills with inert material such as sand or vermiculite, collect in suitable closed containers for disposal, ventilate affected area
Reference to Other Sections: Consult sections on personal protection, disposal, and handling procedures for safer remediation.

Handling and Storage

Handling: Use only in well-ventilated areas, avoid contact with skin, eyes, and clothing, do not eat, drink or smoke in work areas, wash thoroughly after handling
Storage: Store in tightly closed, properly labeled containers, keep at room temperature or cooler, away from incompatible substances such as strong acids and oxidizers, protect from moisture
Specific End Uses: Intended for laboratory, pharmaceutical, or industrial use as designated by relevant health and safety authorities.

Exposure Controls and Personal Protection

Exposure Limits: No occupational exposure limits established by OSHA, ACGIH, or NIOSH
Appropriate Engineering Controls: Local exhaust ventilation recommended, ensure eyewash stations and safety showers are nearby
Personal Protective Equipment (PPE): Hand protection: Wear chemical-resistant gloves (nitrile or neoprene recommended)
Eye protection: Tight-fitting safety goggles or face shield
Skin protection: Use lab coats or chemical-resistant clothing as required
Respiratory protection: Use appropriate respirator if ventilation is inadequate or risk of inhalation exists
Hygiene Practices: Wash hands and face after handling, remove contaminated clothing.

Physical and Chemical Properties

Appearance: White crystalline powder or colorless solid
Odor: Faint, ammoniacal odor
Odor Threshold: Data not available
pH: Approximately 10 (aqueous solution)
Melting Point/Freezing Point: 33-36 °C
Boiling Point/Range: 219-221 °C
Flash Point: 110 °C (closed cup)
Evaporation Rate: Data not determined
Flammability: Not classified as highly flammable
Vapor Pressure: Negligible at room temperature
Vapor Density: Data not available
Relative Density: 1.167 g/cm³
Solubility: Soluble in water, ethanol
Partition Coefficient (n-octanol/water): -2.23 (estimated)
Auto-ignition Temperature: > 385 °C
Decomposition Temperature: Above 200 °C
Viscosity: Not determined
Explosive Properties: Not considered explosive
Oxidizing Properties: Not oxidizing.

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Reactivity: Stable under normal handling; avoid strong acids and oxidizing agents
Hazardous Reactions: Exothermic reactions possible with strong oxidizers
Conditions to Avoid: Excess heat, humidity, sources of ignition, contamination by incompatible substances
Incompatible Materials: Strong acids, acid chlorides, acid anhydrides, oxidizing agents
Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, nitrogen oxides.

Toxicological Information

Acute Toxicity: Oral LD50 (rat) approx. 4000 mg/kg
Skin Corrosion/Irritation: May cause skin irritation and redness with repeated contact
Serious Eye Damage/Irritation: Risk of serious eye irritation
Respiratory or Skin Sensitization: No data available for sensitization in humans; low likelihood, but use caution
Chronic Toxicity: No evidence of mutagenicity, carcinogenicity, or reproductive toxicity
Symptoms Related to Exposure: Rash, redness, eye watering, throat irritation
Further Information: Handling large quantities increases risk of adverse health impacts; routine safety assessments recommend further use-specific evaluation.

Ecological Information

Ecotoxicity: Low aquatic toxicity expected; limited studies suggest minor effects on aquatic invertebrates
Persistence and Degradability: Readily biodegradable in typical environmental conditions
Bioaccumulative Potential: Not expected to bioaccumulate (negative log Kow)
Mobility in Soil: High solubility in water leads to moderate to high mobility through soil
Other Adverse Effects: Spillage into water systems may promote increased biological oxygen demand (BOD); keep out of natural waterways and soil to minimize impact.

Disposal Considerations

Waste Treatment Methods: Dispose of contents and container in accordance with local/regional/national/international regulations
Product Disposal: Small quantities: dilute with water and discharge to controlled sewer if permitted; larger amounts: incinerate under controlled conditions
Container Disposal: Empty containers should be rinsed, then punctured and delivered to an approved waste management facility
Special Precautions: Do not allow product to reach sewage system or water course; avoid disposal in regular trash or unauthorized sites.

Transport Information

UN Number: Not classified as a dangerous good by DOT/TDG/ADR/RID/IMDG/ICAO/IATA
Proper Shipping Name: Not regulated
Hazard Class: Not applicable
Packing Group: Not applicable
Environmental Hazards: None identified under standard shipping practices
Special Precautions for User: Minimize risk during transport by securing containers, keeping upright, and protecting from physical damage.

Regulatory Information

OSHA Status: Not regulated as a hazardous substance
TSCA: Listed on the Toxic Substances Control Act inventory
DSL/NDSL (Canada): Listed
EU (EINECS/ELINCS): Listed under EINECS 208-590-3
REACH Registration: Pre-registered or exempted; consult with suppliers for importation details
SARA Title III: Not subject to reporting requirements under Section 313
California Proposition 65: Not listed
Other Regulatory Info: Observe national and local chemical safety regulations and worker health-protection ordinances where applicable.