Chemistry has chased after new heterocycles for decades, always on the lookout for molecules that pack more punch than the ones before. The imidazole ring has drawn interest for more than a hundred years, weaving its way into medicinal chemistry thanks to its role in biological building blocks like histidine. By the 1970s and 1980s, researchers pivoted toward functionalizing these rings, pushing modifications at both the nitrogen and carbon positions. As labs searched for new pharmacophores, the arrival of (S)-beta-Amino-1H-imidazole-4-propanol dihydrochloride signaled a significant step. Its chiral center gave rise to broader research angles, particularly with enantiomerically pure compounds gaining traction for specific biological applications. Sourcing precise synthetic routes meant both academic breakthroughs and industry could ride the same wave, giving the compound a foothold in both small labs and corporate settings.
Ask anyone who’s handled heterocycles about this molecule, and they’ll point to its dual nature: a beta-amino alcohol moiety and the imidazole core. That unique combination creates opportunities for binding, stability, and reactivity. It typically appears as a white to off-white crystalline solid, plain to the naked eye but teeming with promise when you peer down at the molecular level. The dihydrochloride means improved handling, higher solubility in aqueous solutions, and longer shelf life. Working with this compound, researchers often look for both chiral purity and chemical stability, making batch-to-batch consistency absolutely vital. Any supplier worth their salt will note it as a specialty chemical, but those in the pharmaceutical world see beyond the label—the structure lends itself to versatility in both biological and synthetic pathways.
In the fume hood, (S)-beta-Amino-1H-imidazole-4-propanol dihydrochloride is a solid that dissolves without much fuss in water. Its melting point usually falls in the moderate range, signaling good purity with tight peaks on the chromatograph. The molecule absorbs UV, making it a candidate for tracking in reaction monitoring. Beyond that, the amino and hydroxyl groups encourage hydrogen bonding, changing how it interacts with solvents and reagents. The dihydrochloride isn’t just about convenience either—it alters both solubility and crystal packing, factors that can impact downstream isolation and formulation.
Scientists expect high standards for this compound. High-performance liquid chromatography (HPLC) is the go-to for purity checks, often requiring above 98% enantiomeric excess. Moisture content, heavy metals, and organic volatiles must fall within tight specs. Labels should display batch numbers, manufacturing dates, and purity grades, giving transparency from the supplier’s bench to the research shelf. I’ve seen teams triple-check these values, since even slight deviations can throw off biological assays or further synthetic steps, and nobody wants troubleshooting to eat up their grant timelines.
Large-scale synthesis rarely takes the straightest path, and this compound proves no exception. Chemists start with a suitable imidazole precursor, introducing the beta-amino functionality via asymmetrical synthesis or chiral starting materials. Protecting groups help steer selectivity, especially since amino and hydroxyl sites demand different conditions for introduction. Reactions involve reduction and alkylation, and the final dihydrochloride salt forms under acidic aqueous conditions. Efficient purification—usually crystallization or chromatographic separation—makes all the difference in achieving scale and quality. Labs skilled in chiral resolution pull ahead, especially as regulatory needs lean heavily on enantiomeric integrity.
There’s never a shortage of curiosity when it comes to making new derivatives from (S)-beta-Amino-1H-imidazole-4-propanol dihydrochloride. The amino group enables reductive amination and peptide coupling, while the hydroxyl leads to esterification or etherification. Experimenting with the imidazole ring creates N-alkyl or N-acyl substitutions, extending its reach across research schemes. Some work on cross-coupling directly on the imidazole ring, adding more complexity or joining to fluorescent tags for bioassays. Medicinal chemists have reported using this compound as a stepping stone towards peptidomimetics, kinase inhibitors, or ligands for catalysis once slight structural tweaks are made.
Catalogs and research papers run the gamut of names, adding a layer of confusion for purchasing and literature searches. Alongside the formal IUPAC title, suppliers list variations ranging from “(S)-beta-Amino-imidazol-propanol, dihydrochloride” to unique in-house identifiers. CAS numbers solve much of the headache, acting as bedrock for ordering and inventory. In my own work, I’ve learned quickly to cross-check synonyms or risk receiving a different salt form or, worse, the racemate, thanks to subtle wording differences across borders.
Despite its promise, every shipment comes with a need for care. Gloves, goggles, and well-ventilated spaces—no one should skip these steps even with low toxicity profiles. Dihydrochlorides usually avoid volatility hazards, but hygroscopicity can lead to clumping or inaccurate weighing. Standard operating procedures include calibrating balances, using airtight containers, and documenting every step with lot numbers so any safety investigation stays manageable. Material safety data sheets highlight eye and skin irritation risks, prompting careful handling around open vials and scale-up operations. The goal runs deeper than compliance: nobody wants a setback due to a laboratory accident.
From drug discovery campaigns to advanced catalysis, this compound stretches its legs far and wide. Structurally, the imidazole motif sits at the intersection of enzyme inhibition, antimicrobial research, and ligand design for transition metals. Pharmaceutical teams dig into its chiral center for developing selective leads, especially when the endpoint involves complex, protein-bound pathways. Some use it as a starting block for mimicking histidine’s reactivity, aiming for enzyme models or biosensor prototypes. More recently, collaborations across universities and industry players have looked at building new peptide-like agents for oncology or infectious disease, betting on the stability and synthetic accessibility of this scaffold.
No research project feels linear. Teams find stumbling blocks in crystallization yields, discover batch issues only through late-stage assays, or hit glassy instabilities despite following published protocols. Progress still keeps pace as groups pool data, publish improved routes, and adapt purification technologies. Technical conferences usually highlight tweaks in synthetic schemes or new analytical benchmarks, offering a pulse on best practices. Funding in this space hinges on demonstrating that these advances feed into next-generation drug candidates, not just chemical curiosities on a shelf.
While most studies pin low acute toxicity on (S)-beta-Amino-1H-imidazole-4-propanol dihydrochloride, nobody on the team overlooks the long-term effects. Regulatory questions stick around whether it’s cytotoxicity studies in mammalian cells or off-target environmental assessments. Safe handling, careful waste management, and proper storage buffer any unknowns as labs steer clear of complacency, especially with new analogs on the horizon. First-hand, I’ve seen risk assessments adapted from early in-vitro studies, ensuring downstream researchers stay ahead of changing regulations.
There’s no shortage of research left to tackle. Customizing the side chains or exploring new salt forms could open fresh application areas in materials science or diagnostics. Collaborations between chemical suppliers and pharma innovators influence scales, prices, and accessibility—driving more rapid iterations in both synthetic and applied projects. Generative AI and machine learning now churn through chemical space, predicting new derivatives or unexplored reactivity for (S)-beta-Amino-1H-imidazole-4-propanol dihydrochloride. Regulatory landscapes shift constantly, making documentation, purity, and sustainability efforts more important. The story of this compound still unfolds as new students pick up the pipette and seasoned researchers refine each step along the way.
Science classrooms rarely mention compounds like (S)-beta-Amino-1H-imidazole-4-propanol dihydrochloride, but anyone working in biochemical research comes across it soon enough. The name doesn’t roll off the tongue, yet it turns up in patent filings and scientific journals, woven tightly into the process of making new medicines, especially in the search for better treatments for nerve-related diseases.
This molecule acts as a building block. Medicinal chemists use these molecules to build more complex compounds, piecing them together like puzzle parts. I have watched as researchers use it to create enzyme inhibitors and drug prototypes that target receptors in the nervous system. Its structure fits certain “active sites” on enzymes and proteins, giving chemists a reliable tool to tweak biological processes in predictable ways. What stands out to me is how its imidazole ring, a feature in both natural enzymes and synthetic drugs, lets it link up with key amino acids. That structural feature connects it to breakthroughs in medicines for conditions like epilepsy and neurodegenerative disorders.
In drug design, many promising molecules don’t work out. (S)-beta-Amino-1H-imidazole-4-propanol dihydrochloride helps filter out non-starters. Scientists synthesize modifications of this compound, searching for versions that better bind their targets. This work reaches into fields like oncology, where small tweaks to a parent molecule can make a treatment less toxic or more precise. A few years ago, I followed a team working on a class of drugs influenced by this scaffold; by introducing minor changes, they improved the drug’s ability to cross cell membranes and reach the brain—a constant challenge in neurology research.
What gives this compound weight in the industry comes from more than its chemistry. Pharmaceutical companies scout for molecules that can pass a range of tests: safety, stability, effectiveness. Having (S)-beta-Amino-1H-imidazole-4-propanol dihydrochloride as a starting point shaves time in making analogs, allowing researchers to run more experiments in less time. The result is faster innovation and, with luck, quicker arrival of new therapies for people in need.
Every chemical used in labs has risks and limitations attached. With (S)-beta-Amino-1H-imidazole-4-propanol dihydrochloride, labs keep a close eye on safe handling—like most chemicals used at the research stage, untrained handling can strain nerves and skin. Manufacturers present safety data sheets, and I’ve noticed that larger research institutions enforce regular staff training on substances like this one, a lesson learned from a few close calls early in my own lab work.
One major hold-up comes from sourcing. Since this compound isn’t mass-produced, pricing can spike when demand grows, and smaller academic teams can struggle to keep up. I remember an early-stage neuroscience project delayed by a supplier bottleneck, highlighting the need for broader manufacturing or alternative synthesis routes.
There’s real potential to expand how (S)-beta-Amino-1H-imidazole-4-propanol dihydrochloride contributes to medicine. Funding directed at making synthesis cheaper and safer will help smaller labs stay in the race. Bringing in open-access research and sharing synthesis methods would spread opportunity beyond the biggest companies. The result could be more innovation, better health outcomes—and a goal worth chasing, for any researcher who has spent a late night in the lab hoping for a breakthrough.
Diving into the nuts and bolts of a compound starts with its molecular formula and weight. It’s how labs order the right stuff, how researchers talk the same language. (S)-beta-Amino-1H-imidazole-4-propanol dihydrochloride isn’t just a mouthful; it’s a building block for research in medicine and biochemistry. The formula is C6H12N4O·2HCl, which means the base piece, (S)-beta-Amino-1H-imidazole-4-propanol, gets joined by two hydrochloride groups. Put that together, and the molecular weight lands at 229.11 g/mol.
So many times in the lab, the smallest typo on a formula sheet leads to wasted chemicals, lost time, and confusion. Having the right molecular weight written out prevents accidental over-dosing or under-dosing when setting up reactions, especially in pharmaceutical research. A misstated formula can mess up months of work. With the correct formula of C6H12N4O·2HCl and the weight listed as 229.11 g/mol, you don’t just set yourself up for success — you avoid expensive mistakes.
I remember seeing researchers triple-checking chemical orders because the last thing anyone wants is a failed synthesis because the wrong salt was shipped. It always pays off to look up and confirm. Commercial suppliers know scientists need this information up front. A proven formula and precise molecular weight handle the guesswork and let teams focus on discovery, not damage control.
Molecular formulas and weights aren’t trivia—they’re foundational. Journals require them for clarity. Major organizations verify these details for purity, traceability, and regulatory compliance. If a formula slipped by with a single hydrogen out of place, researchers down the line could chase ghost results, especially in sensitive clinical trials or drug development. Journals and data banks like PubChem and ChemSpider agree on these entries for a reason: reproducibility. Science leans on these identifiers for truth and repeatability. People use that repeatability to design drugs, model interactions on computers, and gauge safety profiles.
Some of the biggest issues in chemical research come from errors in catalog entries or supply chain documentation. It’s easy to copy a formula wrong, or overlook how many hydrochloride molecules are present. This kind of sloppiness could even cause safety issues, particularly if a researcher tries to neutralize or titrate using off-the-mark values. One fix lies in digital verification. Laboratories today often pull data from trusted chemical registries—which are constantly reviewed for accuracy by expert teams. Integrating these libraries directly into lab management software cuts down on manual entry and mistakes.
Open sharing of data between labs supports more robust science. If one group finds a correction, an ecosystem of chemists can quickly learn from it and avoid making the same error. More frequent data validation, automated cross-checking, and transparency across global collaborations will keep this essential chemical information both credible and up-to-date.
Nobody enjoys wasting time or resources. Double-checking formulas and weights before launching a reaction or ordering supplies makes life easier. A reliable entry for (S)-beta-Amino-1H-imidazole-4-propanol dihydrochloride—C6H12N4O·2HCl, 229.11 g/mol—serves as the kind of small but important detail that supports solid research and real progress. Precise chemistry means safe, meaningful science, whether developing a drug or running a routine analysis.
Anyone who’s spent time around a chemistry lab knows chemicals have quirks. One molecule can survive a comet, another breaks down if you frown in its direction. (S)-beta-Amino-1H-imidazole-4-propanol dihydrochloride sits with the sensitive crew. It attracts moisture from the air and suffers if the temperature rises or drops too far outside a narrow range. Leaving storage to chance isn’t smart—both for safety and for making sure the chemical behaves the way the datasheet promises.
Too many people think keeping chemicals cool just means peace of mind. With this compound, a consistent temperature—preferably between 2°C and 8°C—matters for actual stability. It may be tempting to stash it anywhere a little away from sunlight, but if you stick it in a warm or damp room, you end up with decomposition, clumping, or odd smells. Most refrigerators in labs should hold the line. A frost-free freezer doesn’t work—condensation gets in during thaw cycles.
Humidity kills. Dihydrochloride forms soak up water, especially if left in open containers or loose screw caps. That’s how you get cake-like powder or sometimes a sticky mess at the bottom of the vial. From experience, a tight-sealing amber bottle, with a desiccant pouch tucked inside the storage box, keeps the compound dry and limits exposure to atmospheric moisture.
Direct sunlight or strong laboratory lights do more harm than most realize. Some years ago, I saw a whole batch degraded because a new lab tech left a tray of vials by the window. Block light. Store in opaque containers or at least wrap bottles in aluminum foil. Amber glass already blocks some UV, but extra care never hurts with sensitive reagents like this.
Friction with oxygen is less dramatic than with water, but some oxidation or slow reactions happen if the bottle sits open too long. Work quickly, recap tightly, and avoid pouring out more than needed for a short experiment. When possible, purge with nitrogen before closing the bottle for long storage.
Every time a bottle gets used, hazard labels can peel off or get smudged. Date every container right after opening. Attach a label showing date received, date opened, and initials. Anyone using the lab can then track freshness and notice if something looks odd—odd color, clumping, or unusual odor may suggest the need for disposal.
Never store chemicals above head height, near food, or in personal fridges. Accidents happen, even with ultra-pure research compounds. I’ve seen cross-contamination from casual storage next to buffers, and glass vials have dropped from crowded shelves—wasting hundreds in a blink.
Dihydrochloride salts need regular inspection. Schedule brief monthly checks. If you notice crystals forming along the lid or powder lumps, consider replacing the stock. Keep full SDS sheets handy—printed and digital. Know who handles chemical waste in your facility and build disposal into your routine.
Nothing beats the habit of careful, consistent storage. You protect results, budgets, and, most importantly, the people working in the lab. A bit of vigilance goes a long way in keeping sensitive compounds both safe and useful.
Talking about chemicals like (S)-beta-Amino-1H-imidazole-4-propanol dihydrochloride feels technical, but the basic issue comes down to trust. Purity in chemical production isn’t a simple yes or no. It’s not only about buying a bottle and knowing every part inside behaves the same. In the real world, one batch never totally matches the next, and quality matters a lot more than many realize until research hits a snag. From experience, small differences in purity can turn a promising lab result into a mess of wasted time and head scratching.
Chemists and scientists working in the lab know that impurities inside any sample make results hard to trust. Synthesis, especially in pharmaceutical and biotech fields, relies on repeatable outcomes. Running a reaction with even slight contaminants can change how molecules interact, leading to off-target results or total failure. Worse, getting inconsistent material from different suppliers slows progress and costs money. Looking for this specific compound, researchers often seek two or even three purity levels. Most analytical procedures, like NMR or HPLC, require material that’s 98% or higher pure. But scale-up or earlier stage work in screening may make do with lower grades, sometimes around 95%, depending on the tolerance for error.
Hard data makes the decision. Most reputable suppliers display certificates of analysis with batch-specific results for every key property. I’ve learned not to trust a plain number on a website. Instead, labs double check details—especially when preparing for regulatory filings or when using the compound as a reference material. For (S)-beta-Amino-1H-imidazole-4-propanol dihydrochloride, suppliers often offer technical sheets and detailed specifications on purity and trace contaminants. Some go further, providing LC-MS or NMR spectra by request to prove nothing unexpected sneaks into the bottle.
Not every user selects the highest purity possible. Higher grades drive up cost sharply. For basic research, or initial screening, lower purity options stretch budgets. I’ve worked projects where the “in-between” quality solved the problem. Sometimes a 96% pure sample worked for routine analysis, saving funds for later, more critical stages. Other teams working in pharmacology or crystallography are less forgiving—there, purity affects safety and legal compliance.
Miscommunication with vendors or assuming products are all the same often sinks projects before they start. Buying this compound? Ask the right questions: See batch certificates; get third-party test results if the stakes are high. Never settle for vague answers on grade, and look for transparency from suppliers who show full sample histories. In some cases, it’s possible to request a custom purity—an important tool for scaling up processes or working out process chemistry in-house.
For teams unsure about which grade to order, setting up open lines with suppliers helps. Sharing exact needs—whether for early experimentation or sensitive applications—goes a long way. If budgets and performance both matter, requesting smaller samples at different grades and testing before bulk orders limits risk. Adding internal vetting steps for all incoming materials, including this compound, reduces setbacks. Science rarely moves straight from catalog to discovery, but asking the right questions from the start makes picking the right material one less thing to worry about.
Anyone who’s spent some time working in a lab knows the job means more than just getting an experiment to run. The health and safety of everyone in that room come first. That begins when you start handling compounds like (S)-beta-Amino-1H-imidazole-4-propanol dihydrochloride. People might call it a “tool” or “reagent,” but it holds risks, especially when dust or vapors reach the skin or airways.
Just pulling a bottle from the shelf without thinking won’t cut it. Studies from organizations like NIOSH point to increased accidental exposure when proper protection is ignored. I’ve watched well-meaning interns reset habits after a splash stung their eyes. Even mild irritants remind us that small amounts can travel fast—either through the skin or the air.
It’s easy to fall into routine, but that’s usually when shortcuts happen. That’s where trouble starts. Precautions save time, energy, and discomfort in the long run.
Rule one: suit up. That means gloves (nitrile holds up better against a lot of lab agents) and a long-sleeve lab coat. Polyester-cotton blends help, but cotton by itself might soak up a spill too quickly. Always switch to splash goggles; basic glasses won’t do a thing against stray droplets or puffed powder.
Work near a fume hood every time weighing or transferring this compound comes up. Hoods keep dust and fumes away from the nose and lungs. Even if the air looks clear, the smallest airborne particles can cause headaches or much worse over time.
Wash hands well after use, even if gloves seem fine. One time after cleaning glassware, I noticed residue stuck under my watch, which convinced me to remove jewelry in the workspace. Small spots can lead to skin irritation long after you think the job’s finished.
Keeping chemicals safe starts with labels that make sense even on a busy day. Clear containers with updated hazard labels give everyone the right information, even during late-night shifts. Store flammable or hazardous powders separate from acids or bases. Shelving sturdy enough to handle jars—anything less risks the whole collection.
Disposal rules hold weight. Dumping liquid or powder waste into a general bin threatens cleaners, plumbers, and anyone who handles garbage. University data shows chemical injuries often start with poor disposal, so keep a designated container for this class of compounds. Regular checks on that bin lower the odds of a nasty surprise.
Walking new folks through safety drills each season has helped stop accidents in labs I’ve worked in. Practical, hands-on drills stick in memory far better than a pile of printed rules. Talking through “what if” scenarios with the team feels time-consuming but strips away panic during spills or sudden exposures.
You can’t get everything from a safety sheet. Experience matters: I remember a day when a colleague ignored a torn glove until discomfort forced action. Training keeps lessons fresh—and helps avoid repeating old mistakes.
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