MSDS: (S)-2-(methylamino)-1-propanol hydrochloride

Identification

Product Name: (S)-2-(methylamino)-1-propanol hydrochloride
Chemical Formula: C4H12ClNO
Synonyms: (S)-1-Methylamino-2-propanol hydrochloride; (S)-2-(Methylamino)propan-1-ol hydrochloride
CAS Number: 3938-82-9
Manufacturer: Listed on packaging or supplied documentation
Recommended Use: Laboratory research, chemical synthesis, pharmaceutical intermediate
Emergency Contact: Reference on shipping papers and safety documentation
Supplier Information: Available on shipping paperwork or direct from vendor

Hazard Identification

GHS Classification: Acute Toxicity Oral Category 4, Skin Irritation Category 2, Eye Irritation Category 2A
Signal Word: Warning
Hazard Statements: Harmful if swallowed; Causes skin irritation; Causes serious eye irritation
Precautionary Statements: Do not eat, drink or smoke during use; Wash hands thoroughly after handling; Wear protective gloves and eye protection; If swallowed, call a poison center with packaging available; If skin irritation occurs, seek medical advice; In case of eye contact, rinse cautiously with water for several minutes
Potential Health Effects: Inhalation may cause respiratory tract irritation; Ingestion may upset gastrointestinal system and can be toxic; Repeated exposure may dry skin
Label Elements: Exclamation mark pictogram; Safety phrases printed on bottle or container; Emergency redress instructions

Composition / Information on Ingredients

Chemical Name: (S)-2-(methylamino)-1-propanol hydrochloride
Concentration: 98–100%
Impurities: Sweep for trace solvents or minor byproducts below reporting limits as per supplied analytical certificate
Molecular Weight: 125.61 g/mol
RTECS Number: UD7259000
Other Identifiers: Batch code and lot number traceable on container for recall or quality control requirements

First Aid Measures

Inhalation: Move person to fresh air, support breathing as needed, seek medical advice if symptoms such as cough, headache, or shortness of breath develop
Skin Contact: Remove contaminated clothing, rinse area with soap and plenty of water for at least 15 minutes, do not delay medical care for extensive exposures, cover affected area loosely
Eye Contact: Flush eyes with water for at least 15 minutes, use fingers to keep eyelids apart, remove contact lenses if present, immediate medical evaluation advised
Ingestion: Rinse mouth, do not induce vomiting unless directed by medical personnel, provide water if conscious, bring chemical container to show medical responders

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical powder, foam, carbon dioxide
Unsuitable Media: Avoid high-pressure water jets on chemical fires
Specific Hazards: Hydrogen chloride or carbon monoxide possible in thermal decomposition; avoid exposure to combustion vapors
Protective Equipment for Firefighters: Full firefighter turnout gear, self-contained breathing apparatus (SCBA), chemical-resistant gloves
Further Advice: Cool exposed containers with water spray, isolate area, avoid inhaling smoke or fumes, prepare for evacuation if fire impacts storage

Accidental Release Measures

Personal Precautions: Prevent dust formation, wear chemical splash goggles and nitrile gloves, ventilate enclosed areas
Environmental Precautions: Prevent release to surface water, soil, or drains by containing spill with inert absorbent
Cleanup Methods: Use non-combustible absorbent like vermiculite, scoop up material, seal in labeled chemical waste containers, decontaminate area with detergent solution
Disposal: Local, federal regulations guide disposal; contact authorized waste disposal service

Handling and Storage

Handling: Use chemical fume hood, avoid contact with skin or eyes, minimize dust generation, wash hands after use
Storage: Keep container tightly sealed, store in cool dry location, avoid direct sunlight, segregate from incompatible oxidizers or acids
Conditions to Avoid: Heat, moisture, strong acids and oxidizers, open flames
Incompatibilities: Strong acids, strong oxidizing agents, bases

Exposure Controls and Personal Protection

Engineering Controls: Chemical fume hood, local exhaust, avoid confined space accumulation
Personal Protective Equipment: Protective gloves (nitrile, neoprene), chemical safety goggles or face shield, lab coat or apron, closed-toe shoes
Respiratory Protection: NIOSH-approved dust mask if airborne powder present
Hygiene: Remove contaminated clothing, do not eat/drink/smoke during use, routine hand washing

Physical and Chemical Properties

Appearance: White crystalline powder
Odor: Mild, amine-like
Odor Threshold: No data available
pH: 4–6 (water solution)
Melting Point: 175–180 °C
Boiling Point: Decomposes prior to boiling
Solubility: Freely soluble in water, partially soluble in ethanol
Vapor Pressure: Not significant at room conditions
Density: Approximately 1.0 g/cm3
Partition Coefficient: Not determined
Flash Point: Not applicable (solid, non-flammable at ambient)

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Hazardous Reactions: May react exothermically with strong oxidizers or acids
Decomposition Products: Thermal decomposition releases toxic gases, including hydrogen chloride and nitrogen oxides
Conditions to Avoid: Exposure to heat, open flame, moisture
Incompatible Materials: Strong oxidizers, acids, bases

Toxicological Information

Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: LD50 (oral, rat): data not widely published, estimated < 2000 mg/kg
Skin Corrosion/Irritation: Documented irritation with repeated or prolonged contact
Serious Eye Damage/Irritation: Causes moderate to severe eye irritation
Chronic Effects: Not classified as carcinogen, mutagen, or reproductive toxin
Sensitization: Potential for allergic skin response not well established
Additional Data: No reports on long-term human exposure; animal studies suggest manageable toxicity at sub-gram doses

Ecological Information

Ecotoxicity: No measured data available for aquatic species; related compounds toxic at high concentrations
Persistence and Degradability: Expected to be moderately biodegradable in soil and water based on structure-class analogy
Bioaccumulative Potential: Not expected to bioaccumulate significantly due to high water solubility
Mobility in Soil: Mobile; risk of leaching to groundwater if large spills occur
Other Adverse Effects: No evidence of ozone depletion or long-term ecosystem damage

Disposal Considerations

Waste Disposal: Collect as hazardous chemical waste, store in tightly closed labeled containers
Disposal Methods: Incinerate at licensed facility or dispose in accordance with local, national regulations
Containers: Triple rinse before discarding; avoid discharges to environment
Special Instructions: Consult environmental authority for large-scale or bulk disposal

Transport Information

UN Number: UN2811 (Toxic solid, organic, n.o.s.)
Proper Shipping Name: Toxic solid, organic, n.o.s. ((S)-2-(methylamino)-1-propanol hydrochloride)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III (minor danger if transported as intended in original containers)
Marine Pollutant: Not classified
Special Precautions: Avoid contact with skin, dust; package securely to prevent breakage; emergency response documents accompany all shipments

Regulatory Information

US Regulations: SARA Title III Section 313 not listed; TSCA inventory review recommended; OSHA hazard classified
EU Regulations: REACH pre-registration supported by supplier as requested; CLP classified as irritant
Other Regulations: Not listed on international prohibited substance lists; workplace exposure limits not established
Labeling: GHS pictograms and hazard statements appear on package
Recordkeeping: Maintain purchase and handling records as required for restricted chemicals