Product Name: (S)-(+)-2-Chloro-2-Propanol
CAS Number: 1518-37-8
EC Number: 216-160-6
Chemical Formula: C3H7ClO
Synonyms: (S)-2-Chloropropan-2-ol, (S)-1-Chloro-2-propanol
Recommended Use: Laboratory chemical, intermediate for synthesis
Manufacturer: Listed by supplier, with emergency contact number
Hazard Classification: Eye irritation (Category 2), Skin irritation (Category 2), Acute toxicity oral (Category 4)
GHS Label Elements: Exclamation mark pictogram, Signal word: Warning
Hazard Statements: Harmful if swallowed, causes skin irritation, causes serious eye irritation
Precautionary Statements: Avoid breathing dust or vapors, wear protective gloves and eye protection, wash hands thoroughly after handling
Other Hazards: May be harmful if inhaled or absorbed through skin; vapor may cause respiratory tract irritation
Chemical Name: (S)-(+)-2-Chloro-2-Propanol
CAS Number: 1518-37-8
Concentration: ≥ 99% pure
Impurities: No significant impurities classified as hazardous
Inhalation: Move affected person to fresh air, keep at rest, seek medical attention if symptoms develop
Skin Contact: Remove contaminated clothing, wash thoroughly with soap and water; seek medical advice if irritation persists
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses, continue rinsing, get medical attention
Ingestion: Rinse mouth, do not induce vomiting, seek medical attention immediately
Key Symptoms: Irritation to eyes, skin, respiratory tract; possible nausea, headache
Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, alcohol-resistant foam
Unsuitable Extinguishing Media: Water jets (may spread fire)
Specific Hazards: Forms toxic gases, such as hydrogen chloride and carbon monoxide, under combustion
Protective Equipment: Full protective gear, self-contained breathing apparatus
Firefighting Procedures: Avoid inhalation of fumes, keep containers cool with water spray, evacuate personnel to a safe area
Personal Precautions: Provide adequate ventilation, use personal protective equipment, avoid contact with skin, eyes, and clothing
Environmental Precautions: Prevent spilled material from entering drains, soil, or natural waters
Methods for Cleanup: Absorb spill with inert material (sand, earth), scoop up and place in suitable chemical waste container, wash site with water after material pickup
Emergency Procedures: Evacuate area, restrict access, ventilate area
Safe Handling: Use only in well-ventilated areas, avoid inhalation of vapors, prevent contact with eyes and skin, keep away from sources of ignition
Storage Conditions: Store tightly closed in a cool, dry, well-ventilated place away from incompatible substances (strong oxidizers, acids, bases)
Incompatible Materials: Strong oxidizing agents, acids, bases, reducing agents
Safe Storage Requirements: Keep container tightly closed, segregated storage for chemicals
Exposure Limits: No occupational exposure limits established; recommended to minimize exposure
Engineering Controls: Use fume hood, local exhaust ventilation; maintain eye-wash stations and safety showers
Personal Protective Equipment: Chemical splash goggles, compatible gloves (nitrile, neoprene), laboratory coat, avoid open-toed footwear
Respiratory Protection: Use NIOSH-approved respirator in case of insufficient ventilation
Hygiene Measures: Wash hands before breaks and after work, do not eat or drink in working area
Appearance: Colorless to light yellow liquid
Odor: Slight, characteristic
Melting Point: -44 °C
Boiling Point: 127 °C
Flash Point: 33 °C (closed cup)
Evaporation Rate: Not determined
Flammability: Flammable in presence of ignition sources
Vapor Pressure: 12 mmHg at 25 °C
Vapor Density: Greater than 1 (air = 1)
Relative Density: 1.11 g/cm³
Solubility: Miscible with water and organic solvents
Partition Coefficient (n-octanol/water): Not available
Auto-ignition Temperature: Not determined
Viscosity: Not determined
Chemical Stability: Stable under recommended handling and storage conditions
Reactivity: Reacts with strong oxidizers; forms explosive mixtures with air at elevated temperatures
Potential Hazardous Reactions: May generate toxic gases on decomposition (hydrogen chloride, phosgene)
Conditions to Avoid: Heat, sparks, open flame, sources of ignition, contact with incompatible substances
Incompatible Materials: Oxidizing agents, strong acids, bases
Decomposition Products: Hydrogen chloride gas, phosgene, carbon monoxide, carbon dioxide
Acute Toxicity: Harmful if swallowed (oral LD50 in rats: ~530 mg/kg)
Skin Corrosion/Irritation: May cause irritation on prolonged contact
Serious Eye Damage/Irritation: Causes eye irritation, redness, watering
Respiratory Sensitization: May cause irritation to respiratory tract if inhaled
Germ Cell Mutagenicity: Not classified
Carcinogenicity: Not listed as a carcinogen by IARC, NTP, or OSHA
Reproductive Toxicity: No evidence from available data
Target Organ Effects: Central nervous system, eyes, skin
Symptoms of Overexposure: Cough, drowsiness, headache, nausea;
Ecotoxicity: Harmful to aquatic life, no long-term data available
Mobility in Soil: Likely to leach into groundwater upon spillage, high mobility due to solubility
Persistence and Degradability: Not readily biodegradable; hydrolyzes slowly in water
Bioaccumulative Potential: Expected to have low bioaccumulation
Other Adverse Effects: Avoid release to environment, precaution to prevent penetration into sewers
Waste Treatment Methods: Incinerate in chemical incinerator with afterburner and scrubber, always comply with federal, state, and local regulations
Disposal of Contaminated Packaging: Rinse thoroughly, then dispose of as hazardous waste
Precautions: Keep out of drain, prevent spillage, avoid contamination with incompatible materials
UN Number: 1992
UN Proper Shipping Name: Flammable liquid, toxic, n.o.s. ((S)-(+)-2-chloro-2-propanol)
Transport Hazard Class: 3 (Flammable liquids), 6.1 (Toxic substances)
Packing Group: III
Environmental Hazards: Not classified as marine pollutant
Special Precautions: Store upright, away from incompatible cargo, emergency procedures for spillage
Regulatory Labels: Flammable liquid, toxic
OSHA Status: Not classified as highly hazardous; handle per Laboratory Standard
SARA Title III: Not reportable under Sections 302, 304, 313; Section 311/312 covers hazards
TSCA Status: Listed
RCRA Status: Considered hazardous if discarded as waste
DSL/NDSL (Canada): Check inventory status
Other Regulations: All components comply with REACH requirements, hazard chemical under local workplace safety standards