Product Name: (S)-1-Amino-3-chloro-2-propanol hydrochloride
Chemical Formula: C3H9Cl2NO
Synonyms: (S)-3-chloro-2-hydroxypropylamine hydrochloride
Recommended Use: Chemical research, synthesis of pharmaceutical intermediates
Supplier Information: Manufacturer’s contact and address required on original container
Emergency Contact: Refer to label or regional Poison Control Center
GHS Classification: Acute toxicity (oral, dermal, inhalation), skin irritation, eye damage
Signal Word: Warning
Hazard Statements: Harmful if swallowed; Causes skin and serious eye irritation; May cause respiratory irritation
Pictograms: Exclamation mark
Precautionary Statements: Avoid contact with eyes, skin, and clothing; Use personal protection; Wash after handling
Potential Health Effects: Exposure may cause burning sensation, coughing, difficulty breathing, pain in eyes or skin
Chemical: (S)-1-Amino-3-chloro-2-propanol hydrochloride
CAS Number: 132900-45-3
EC Number: Not assigned
Concentration: 98–100%
Impurities: Minor, exact composition provided on specific batch COA
Molecular Weight: 146.02 g/mol
Eye Contact: Rinse immediately with copious amounts of water for at least 15 minutes, lift eyelids, seek medical advice
Skin Contact: Remove contaminated clothing, wash area thoroughly with water and soap, get medical help if irritation persists
Inhalation: Move to fresh air, help breathing if affected, consult a doctor
Ingestion: Rinse mouth, never give anything by mouth to an unconscious person, seek immediate medical attention
Note to Physician: Treat symptomatically, monitor vital functions, consider delayed effects
Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical powder, carbon dioxide
Unsuitable Extinguishing Media: High-volume water jets can spread contamination
Hazards from Combustion: Hydrogen chloride gas, nitrogen oxides, carbon monoxide, irritating fumes
Protective Equipment for Firefighters: Full-body protection, self-contained breathing apparatus
Special Procedures: Cool containers exposed to fire, control run-off to prevent contamination
Personal Precautions: Evacuate area, ventilate space, use personal protective gear—gloves, goggles, protective clothing
Environmental Precautions: Avoid discharge to drains, water sources, and soil
Methods for Clean-Up: Collect spill with inert absorbent, keep material for proper disposal
Decontamination: Wash area thoroughly with water and mild detergent after pick-up
Reporting: Notify local authorities if large amounts enter environment
Handling: Use in fume hood, avoid inhaling dust, contact with skin and eyes, keep container tightly sealed
Hygiene Practices: Wash thoroughly after use, change contaminated clothing, no eating or drinking during handling
Storage: Store in a tightly closed container, dry, cool, well-ventilated area, protected from incompatible substances
Incompatibles: Strong oxidizers, strong acids, certain metals
Specific Storage Conditions: Maintain product in original packaging, avoid temperature extremes
Exposure Limits: No occupational exposure limits set by OSHA or ACGIH
Engineering Controls: Use with exhaust ventilation, eye wash stations, safety showers
Personal Protection: Gloves resistant to chemicals (nitrile or neoprene), protective clothing, chemical splash goggles, appropriate respirator if exposure risk exists
Work Practices: Avoid contact with skin, eyes, and clothing, use protective barriers where necessary
Appearance: White to off-white crystalline powder
Odor: Odorless or mild amine scent
Melting Point: 210–214°C (decomposition)
Boiling Point: Not available
Solubility: Soluble in water, slightly soluble in ethanol
pH (1% solution): Approximately 5.0–7.0
Density: 1.39 g/cm³ at 20°C
Partition Coefficient: No data available
Vapor Pressure: Negligible at room temperature
Chemical Stability: Stable at recommended storage conditions
Decomposition Products: Hydrogen chloride, nitrogen oxides, carbon oxides on combustion
Hazardous Reactions: Can react with oxidizing agents, acids, or alkali
Conditions to Avoid: Excess heat, open flames, incompatible materials
Polymerization: Not known to occur
Incompatible Materials: Avoid mixing with strong oxidants and strong acids
Routes of Exposure: Eyes, skin, ingestion, inhalation
Acute Toxicity: Data limited, may cause gastrointestinal distress, respiratory symptoms, skin and eye irritation
Chronic Effects: Prolonged exposure could cause dermatitis or respiratory discomfort
Carcinogenicity: No components classified as carcinogenic by IARC, NTP, or OSHA
Mutagenicity: Not reported
Reproductive Effects: No conclusive animal or epidemiological data
Sensitization: Some risk of allergic skin or respiratory reaction
Ecotoxicity: No specific data found, avoid large releases
Persistence and Degradability: Likely to degrade slowly in the environment
Bioaccumulation Potential: Limited bioaccumulation expected
Mobility in Soil: Soluble, may leach into groundwater if not properly contained
Other Effects: Do not allow product or contaminated run-off to reach major waterways
Waste Disposal Methods: Dispose as hazardous waste according to federal, state, and local regulations
Contaminated Packaging: Triple rinse before disposal, label for chemical residue
Disposal Precautions: Always follow responsible chemical disposal practices, consult authorized disposal contractor
Prohibited Actions: Do not dump into sewer, soil, or water bodies
UN Number: Not classified for transport (consult shipment documentation for updates)
Transport Hazard Class: Not regulated under most international regulations
Packing Group: Not assigned
Special Precautions: Protect from damage and moisture during transit
Emergency Response Guide: Carry Safety Data Sheet, use personal protection for accidental spillage
Labeling Requirements: GHS pictograms, hazard warnings, supplier identifier
TSCA Status: Not listed or subject to pre-manufacture notification exemption
REACH Status: Not registered; inquire with supplier about current status
SARA 313: No component listed
California Proposition 65: Not listed
Other Regulations: Check with local, state, and federal agencies for restrictions or reporting
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