Product Name: (S)-1-(3-(2-(7-Chloro-2-Quinolinyl)Ethenyl)Phenyl)-3-(2-(1-Hydroxy-1-Methylethyl)-Phenyl)Propanol
Chemical Family: Quinoline derivatives
Synonyms: None available
Manufacturer: Data available upon request
Product Use: Research, synthesis of analytical standards, or intermediates in pharmaceutical processes
Contact Information: Manufacturer phone, emergency contact, and email available on procurement documentation.
CAS Number: Refer to laboratory inventory or supplier documentation for specific identifier.
GHS Classification: Acute Toxicity (Oral/Derma/Inhalation): Category 4; Eye Irritation: Category 2A; Skin Sensitisation: Category 1.
Label Elements: Signal Word: WARNING; Hazard Pictograms: Exclamation mark.
Hazard Statements: Harmful if swallowed, in contact with skin or if inhaled. Causes serious eye irritation. May cause allergic skin reaction.
Precautionary Statements: Avoid breathing dust or vapors; use personal protective equipment; wash hands thoroughly after handling; do not eat, drink or smoke while handling substance.
Potential Health Effects: May cause respiratory tract irritation, dizziness, headaches, skin rashes.
Environmental Concerns: Hazardous to aquatic life with long lasting effects.
Chemical Name: (S)-1-(3-(2-(7-Chloro-2-Quinolinyl)Ethenyl)Phenyl)-3-(2-(1-Hydroxy-1-Methylethyl)-Phenyl)Propanol
PURITY: Not less than 98%
EC Number: Data not assigned
Other Components: Residual solvents and process-related impurities controlled below 0.5% (w/w).
Stabilizers/Preservatives: Not present.
Inhalation: Move individual to fresh air with speed; provide assisted respiration if breathing becomes difficult, keep at rest. Immediate medical attention for ongoing symptoms.
Skin Contact: Remove contaminated clothing; flush affected skin with ample cool water and mild soap, minimum fifteen minutes. Do not apply ointments or creams before medical assessment.
Eye Contact: Rinse thoroughly at eye-wash station for fifteen minutes; seek prompt medical evaluation.
Ingestion: Rinse mouth; never induce vomiting without medical instruction. Contact poison control center or emergency medical services promptly.
Self-Protection: Use gloves, goggles, and face mask as barriers during all first aid.
Suitable Extinguishing Media: Foam, dry chemical, carbon dioxide, or water spray can be effective for controlling fires involving quinoline derivatives.
Unsuitable Media: Do not use direct high-pressure water jet.
Fire Hazards: Product may release toxic gases such as hydrogen chloride, nitrogen oxides, and carbon oxides upon combustion.
Special Protective Equipment: Full firefighting suit, NIOSH certified self-contained breathing apparatus, gloves.
Flammability: Combustible dusts can form explosive mixtures with air.
Advice for Firefighters: Isolate area, remove personnel from downwind, prevent run-off from entering water bodies or sewers.
Personal Precautions: Wear gloves, impervious gown, NIOSH-approved respirator, and safety goggles; do not touch or walk through spilled product.
Environmental Protection: Prevent further leakage or spillage if safe to do so—do not allow to enter drainage system.
Methods for Clean-Up: Gently sweep up spilled material using spark-proof tools; transfer to sealed waste container clearly labelled for incineration.
Solid Spill: Use absorbent, non-combustible material (vermiculite, sand) to trap dust and residues; avoid creation of airborne particles.
Decontamination: Wash down surface with soap and water; ventilate area thoroughly before reuse.
Disposal: Handle as hazardous chemical waste according to local, federal, and state regulations.
Safe Handling: Only trained personnel should handle; keep containers tightly closed; avoid direct contact with material; apply engineering controls in work space.
Avoid Exposure: Keep away from ignition sources. Do not breathe dust or vapors.
Storage Conditions: Store in a dry, well-ventilated facility at 2°C – 8°C; protect from light, humidity, and incompatible substances (oxidizers, acids).
Container Material: Use sealed glass, HDPE, or equivalent containers with clear hazardous material labelling.
Special Requirements: Regularly inspect storage locations for leaks and container integrity.
Engineering Controls: Chemical fume hood; local exhaust; general ventilation sufficient for particulate capture.
Personal Protective Equipment: Lab coat, chemical resistant gloves (nitrile or neoprene), splash goggles, fitted respirator for dust.
Hygiene Measures: Wash hands and arms before breaks, lunches, or leaving laboratory; remove and wash contaminated clothing.
Exposure Limit Values: No occupational exposure limit established for compound; minimize exposure using prudent industrial hygiene practices.
Environmental Controls: Avoid release to the environment; handle waste liquids and solids as hazardous.
Appearance: Off-white to pale yellow crystalline powder.
Odor: Mild, aromatic or faintly chemical.
Molecular Formula: C29H27ClNO2
Molecular Weight: 458.99 g/mol
Melting Point: 120–128°C
Solubility: Low water solubility; soluble in ethanol, DMSO, and chloroform.
pH (Solution): Not applicable for the solid form; weakly basic in DMSO solution.
Vapor Pressure: Data unavailable; generally low volatility.
Boiling Point: Decomposes before boiling.
Partition Coefficient (Log Pow): Estimated > 3, denoting high hydrophobicity.
Other Properties: Non-volatile, non-corrosive as solid.
Chemical Stability: Stable at room temperature in closed containers under inert atmosphere and away from moisture.
Reactivity: Strong oxidizers, strong acids, or bases may initiate decomposition.
Hazardous Reactions: None expected during expected use.
Decomposition Products: Burning generates carbon monoxide, carbon dioxide, hydrogen chloride, nitrogen oxides.
Conditions to Avoid: High temperature, direct sunlight, moisture, or contact with incompatible materials for prolonged periods.
Acute Toxicity: Harmful; estimated oral/dermal/inhalation LD50 in rat models exceeds 200 mg/kg but less than 2000 mg/kg.
Skin Corrosion/Irritation: Mild to moderate irritation possible upon contact.
Serious Eye Damage/Irritation: May cause redness, tearing, and pain.
Respiratory Sensitization: Dust can irritate upper respiratory tract and provoke cough or shortness of breath.
Skin Sensitization: Some users may experience allergic reactions.
Chronic Exposure: Repeated exposure leads to possible liver, kidney, or nervous system injury.
Carcinogenicity/Mutagenicity: No specific data available; not listed by IARC, NTP, or OSHA.
Other Information: Work with caution; minimize direct skin and inhalation exposure.
Aquatic Toxicity: Toxic to aquatic organisms; risk of long-term adverse effects in aquatic environments.
Persistence and Degradability: Compound exhibits persistence; not readily biodegradable.
Bioaccumulative Potential: High partition coefficient suggests potential to bioaccumulate in aquatic organisms.
Mobility in Soil: Limited mobility; strong adsorption to soil particles predicted.
Other Adverse Effects: Spillage may impact sediment-dwelling flora and fauna; take all precautions against accidental release.
Ecotoxicological Data: Fish and invertebrate LC50/EC50 > 10 mg/L, but chronic exposure reduces survival.
Waste Codes: Not specifically regulated, but best handled as hazardous under local, state, and federal guidelines.
Disposal Methods: Incinerate waste in chemical incinerator equipped with scrubber; do not dispose into sewer or surface water.
Empty Container Precautions: Triple-rinse with suitable solvent; render container unfit for reuse; dispose of as hazardous chemical waste.
Contaminated Packaging: Collect with chemical waste material for proper disposal; never discharge into environment.
Disposal Personnel: Trained personnel with access to personal protection and chemical spill clean-up equipment.
UN Number: Not listed; ship as limited quantity or under non-hazardous classification based on authority guidelines.
Proper Shipping Name: Chemicals, N.O.S. (not otherwise specified).
Hazard Class: Consult regulatory body; generally not regulated as dangerous during ground shipping.
Packing Group: III if classified.
Environmental Hazards: Marine pollutant label recommended.
Transport Regulations: Ensure secondary containment and tamper-proof packaging for air, sea, or overland freight; document chain of custody.
US Regulations: Not specifically listed in EPA TSCA inventory; consider substances of unknown toxicity as hazardous.
SARA Title III: Not subject to reporting under Sections 302, 304, and 313, but prudent practices dictate notification of any significant spills.
OSHA Status: Hazardous chemical based on OSHA Hazard Communication Standard.
European Union: No REACH registration number; handled as hazardous preparation.
Canada: Not listed on DSL/NDSL.
Other Local Controls: Follow institutional and laboratory chemical safety rules strictly. Safety data available to all handlers.
Labelling: Ensure GHS compliant labels remain intact during storage, handling, and disposal, with provisions for emergency response.
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