Product Name: (R)-(-)-Propylene Glycol 1-Methyl Ether
Synonyms: (R)-(-)-1-Methoxy-2-propanol, Propylene glycol monomethyl ether (PGME) (R-configuration)
CAS Number: 34590-94-8
Recommended Use: Solvent for industrial, laboratory, and cleaning applications
Supplier Details: Manufacturer and contact specifics provided directly on product label and technical bulletin
Emergency Phone Number: Refer to product packaging or Safety Office directory for regional numbers
Classification: Flammable liquid (Category 3), Eye irritation (Category 2A), Specific target organ toxicity – single exposure (Category 3)
Signal Word: Warning
Hazard Statements: Flammable liquid and vapor. Causes serious eye irritation. May cause drowsiness or dizziness.
Pictograms: Flame, Exclamation Mark
Precautionary Statements: Keep away from heat, hot surfaces, sparks, open flames. Avoid breathing vapors. Use only outdoors or in well-ventilated areas. Wear eye protection and protective clothing.
Chemical Name: (R)-(-)-Propylene Glycol 1-Methyl Ether
Concentration: 99% or greater
CAS Number: 34590-94-8
Impurities: Trace impurities including water & other isomers, less than 1% total
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. Seek medical advice if irritation persists.
Skin Contact: Remove contaminated clothing. Wash affected area with mild soap and plenty of water. Get medical attention if skin irritation or rash occurs.
Inhalation: Remove person to fresh air and keep comfortable for breathing. Get medical attention if symptoms persist or worsen.
Ingestion: Rinse mouth with water. Do not induce vomiting unless advised by medical personnel. Get medical help or contact a Poison Center as soon as possible.
Most Important Symptoms: Eye redness, watering, dizziness, drowsiness, headache, and skin dryness
Note to Physicians: Treat symptomatically and provide supportive care as needed
Suitable Extinguishing Media: Use water spray, dry chemical, foam, or carbon dioxide.
Unsuitable Extinguishing Media: Direct water stream may spread fire.
Specific Hazards: Vapor may form explosive mixtures with air, containers can rupture under fire conditions, produces carbon monoxide and carbon dioxide upon combustion.
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear.
Special Precautions: Move containers from fire area if safe, cool containers with water spray to prevent pressure build-up or explosion.
Personal Precautions: Evacuate area and ensure adequate ventilation. Eliminate sources of ignition. Wear chemical-resistant gloves, goggles, and protective clothing.
Environmental Precautions: Prevent entry into waterways, drains, basements, or confined areas.
Methods for Cleanup: Contain spilled material with inert material such as sand or earth. Collect residue into containers for proper disposal. Clean area with water afterward.
Reference to Other Sections: Refer to Exposure Controls, Disposal Considerations, and Handling and Storage
Handling: Avoid inhalation of vapors and contact with skin and eyes. Don’t eat, drink, or smoke during use. Use spark-proof tools and explosion-proof equipment. Work in well-ventilated areas.
Storage: Store in tightly sealed containers, away from direct sunlight, sources of heat, oxidizing agents, acids, and alkalis. Keep temperature below 35°C to prevent evaporation or pressure build-up. Label all containers clearly. Store large quantities in fireproof areas with spill containment.
Exposure Limits: OSHA PEL: 100 ppm TWA, ACGIH TLV: 50 ppm TWA (skin)
Engineering Controls: Use local exhaust ventilation or other engineering controls to keep airborne levels below exposure limits.
Personal Protective Equipment: Chemical splash goggles, gloves resistant to organic solvents, lab coats or chemical aprons, flame-resistant clothing for larger scale work
Respiratory Protection: Use NIOSH or MSHA-approved respirator if exposure cannot be controlled by ventilation.
Hygiene Measures: Wash hands thoroughly after handling, remove and wash contaminated clothing before reuse. Avoid contact with skin and eyes.
Appearance: Clear, colorless liquid
Odor: Mild, ether-like
pH: Not available
Melting Point: -96°C
Boiling Point: 120°C
Flash Point: 39°C (closed cup)
Evaporation Rate: Slower than ether
Flammability: Flammable liquid
Vapor Pressure: 11 mmHg at 20°C
Vapor Density: 3.1 (air = 1)
Solubility: Miscible with water in all proportions
Partition Coefficient (log Kow): -0.43
Auto-Ignition Temperature: 330°C
Decomposition Temperature: Not specified
Viscosity: 1.7 mPa·s at 25°C
Chemical Stability: Stable under recommended storage and handling conditions.
Reactivity: Reactive with strong oxidizing agents, acids, and bases.
Conditions to Avoid: Heat, flames, sparks, and other sources of ignition. Prolonged exposure to moist air or water.
Incompatible Materials: Strong oxidants (such as chlorine, nitric acid), strong bases, acids, halogens.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, formaldehyde under fire or extreme heat.
Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Toxicity: LD50 Oral (rat) 4,015 mg/kg
Skin Corrosion/Irritation: May cause moderate skin irritation or dryness with prolonged exposure
Serious Eye Damage/Irritation: Causes eye irritation, redness, and watering
Respiratory or Skin Sensitization: Not classified as respiratory or skin sensitizer
STOT – Single Exposure: Drowsiness or dizziness possible at high doses
Carcinogenicity: Not classed as carcinogen by IARC, NTP, OSHA
Reproductive Toxicity: No definitive studies showing reproductive effects at typical exposure levels
Chronic Effects: Long-term exposure may contribute to central nervous system effects including headaches and drowsiness
Symptoms Related to Exposure: Eye irritation, headaches, dizziness, nausea, dry skin
Ecotoxicity: Harmful to aquatic life in high concentrations; LC50 (fish, 96 hr): 20,800 mg/L
Persistence and Degradability: Readily biodegradable by environmental bacteria
Bioaccumulative Potential: Low likelihood, low log Kow reading
Mobility in Soil: Product highly mobile in soil, leaches into groundwater
Other Adverse Effects: Significant spills may impact aquatic life and depurate oxygen from water bodies; avoid unintentional release to environment
Waste Treatment Methods: Dispose as hazardous waste in compliance with federal, state, and local regulations. Use licensed chemical disposal contractor.
Product/Container Disposal: Do not reuse empty containers. Rinse thoroughly, then dispose through incineration or approved waste collection service.
Environmental Precautions: Prevent further leakage or spillage. Do not allow product to reach sewers, waterways, or soil.
UN Number: UN 3092
Proper Shipping Name: 1-Methoxy-2-Propanol
Transport Hazard Class: 3 (Flammable Liquid)
Packing Group: III
Label: Flammable liquid
Environmental Hazards: Not a marine pollutant
Special Precautions: Follow all regulations when transporting; use sealed, labeled drums in upright position with secure loading methods
Additional Info: Check specific local, national, or international regulations before shipment
TSCA Status: Listed in the United States Toxic Substances Control Act Inventory
DSL/NDSL (Canada): Listed
EINECS/ELINCS (Europe): Listed
OSHA Hazards: Classified as hazardous chemical
SARA Title III Sections 311/312: Fire hazard, acute hazard
SARA Title III Sections 313: Not subject to reporting
REACH Status (EU): Registered
California Proposition 65: Not listed as causing cancer or reproductive toxicity
Other Regulation: Follow all local and workplace regulations for chemical storage, handling, labeling, and worker training
Providing high-quality chemical products and logistics solutions for global trade partners.
