Product Name: (R)-3-Amino-1,2-propanediol
Synonyms: (R)-2-Amino-1,3-propanediol; (R)-Serinol
Chemical Formula: C3H9NO2
CAS Number: 616-29-5
Recommended Use: Research, chemical synthesis, pharmaceuticals
Manufacturer Information: Reliable chemical suppliers distribute this compound, requiring lab-level safety handling.
Emergency Contact: Access to local medical services, poison control, and chemical safety teams supports emergency management.
GHS Classification: Serious Eye Damage/Eye Irritation (Category 2A), Skin Irritation (Category 2), Acute Toxicity (Oral, Category 4)
Label Elements: Signal word: Warning; Pictogram: Exclamation mark
Hazard Statements: Causes skin irritation and serious eye irritation, can be harmful if swallowed, contact may cause allergic reaction
Precautionary Statements: Wear gloves and goggles, avoid breathing dust or fume, wash hands thoroughly after handling, do not eat or drink near working area, store locked away, dispose of contents as required by local law
Other Hazards: Prolonged exposure increases risk of skin problems or respiratory irritation, not classified as carcinogenic, but unnecessary inhalation or direct contact risks remain
Chemical Name: (R)-3-Amino-1,2-propanediol
Synonyms: (R)-Serinol
CAS Number: 616-29-5
EC Number: 210-470-3
Purity: Higher than 98 percent in typical research grade lots
Impurities: None declared in specification, may contain trace moisture unless stored in sealed containers
Inhalation: Remove to fresh air, keep at rest, call for medical attention if symptoms develop
Skin Contact: Remove contaminated clothing, wash with plenty of water and mild soap, monitor for rash or irritation, seek medical advice for persistent effect
Eye Contact: Rinse cautiously with plenty of water for several minutes, remove contact lenses if present, continue rinsing, consult physician
Ingestion: Rinse mouth thoroughly, do not induce vomiting, drink water, seek immediate medical care if significant quantity ingested
Most Important Symptoms and Effects: Eye redness, tearing, itching or discomfort, nausea if swallowed, sore throat from dust inhalation
Notes to Doctor: Supportive care and symptomatic treatment, no specific antidote, ensure airway management in case of pulmonary complications
Suitable Extinguishing Media: Foam, dry chemical powder, or CO2 can control small fires involving amino alcohols
Specific Hazards: Burns readily, may give off nitrogen oxides or carbon monoxide when combusted
Protective Equipment: Firefighters require self-contained breathing apparatus, full protective clothing
Firefighting Instructions: Apply cooling water sprays to unaffected containers, avoid inhaling combustion fumes, evacuate area if significant fire
Hazardous Combustion Products: Carbon monoxide, nitrogen oxides, ammonia fumes in case of incomplete burning
Personal Precautions: Use gloves, protective glasses, dust mask or respirator, prevent skin and eye contact
Environmental Precautions: Prevent entry into waterways, sewage, or soil, notify proper authorities if contamination occurs
Methods for Clean-Up: Absorb solid with inert material, place in chemical waste container, ventilate affected area, thoroughly wash surface with water and detergent
Spill Response: Small spills can be swept up and contained safely, larger spills demand evacuation and expert cleanup
Handling: Wear gloves, goggles, and dust mask, use only in well-ventilated space, avoid ingestion and direct skin contact, keep away from incompatible agents such as strong acids
Storage: Store in tightly sealed container, cool and dry cabinet, protect from moisture, keep out of reach of children, avoid excessive heat or direct sunlight, segregate from oxidizers
Hygiene Measures: Wash hands after handling, remove contaminated clothing before leaving workspace, never eat or smoke in chemical work zones
Control Parameters: No established exposure limits exist for this compound, best practice calls for general occupational exposure rules applied to similar amino alcohols
Engineering Controls: Use chemical fume hood or local exhaust to keep airborne dust below detectable range
Personal Protective Equipment: Safety goggles, nitrile or latex gloves, laboratory coat, respirator if dust or mist becomes significant
Environmental Exposure Controls: Capture vapor or dust, install spill trays, practice good chemical housekeeping to avoid contamination
Physical Appearance: White to off-white crystalline solid
Odor: Mild, amine-like scent
Molecular Weight: 91.11 g/mol
Melting Point: 50-55°C
Boiling Point: Decomposes before boiling
Solubility: Highly soluble in water and alcohols
pH: Forms basic aqueous solution
Vapor Pressure: Negligible at room temperature
Partition Coefficient: Log Pow -1.24
Flash Point: Not available; standard procedures call for treating as flammable solid in dust form
Density: Around 1.15 g/cm³
Viscosity: Not applicable for solid
Evaporation Rate: Not measurable under room conditions
Chemical Stability: Stable under recommended storage and handling, decomposes at elevated temperatures
Conditions to Avoid: High humidity, open flame, high heat, strong oxidizers or acids
Incompatible Materials: Strong acids, acid chlorides, strong oxidizing agents
Hazardous Decomposition Products: Ammonia, nitrogen oxides, carbon monoxide under fire conditions
Hazardous Polymerization: Does not occur
Acute Toxicity: Harmful if swallowed; animal studies suggest oral LD50 above 500 mg/kg
Skin Corrosion/Irritation: May cause moderate to severe irritation on prolonged contact
Serious Eye Damage/Irritation: Prompts redness, tearing, discomfort, possible damage with prolonged contact
Respiratory Sensitization: Dust or vapor can cause mild respiratory irritation; improper use increases risk
Chronic Effects: No evidence of carcinogenic, mutagenic, or reprotoxic potential; limited long-term data
Other Information: Handling while using gloves, goggles, and with good lab hygiene minimize risks raised in published data
Ecotoxicity: No specific data for this compound, but low-level aqueous release may cause mild stress in aquatic life, similar to simple amines
Persistence and Degradability: Readily biodegradable by typical soil and wastewater bacteria
Bioaccumulation Potential: Low due to high water solubility, unlikely to persist in the environment
Mobility in Soil: Moves quickly through soil with water, likely breakdown under normal conditions
Other Adverse Effects: Uncontrolled disposal in large quantity may upset local water chemistry, careful containment during waste disposal remains fact-based practice
Waste Treatment Methods: Collect in chemical waste containers, do not allow into drains, canals, or soil
Disposal Route: Dispose through licensed waste disposal contractor according to local, regional, and national regulations
Contaminated Packaging: Rinse containers thoroughly before disposal or recycling, destroy unused batches per hazardous waste guidelines
Special Precautions: Only trained personnel should manage chemical waste, full PPE required throughout disposal process
UN Number: Not classified as hazardous for transportation
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not assigned
Packing Group: Not assigned
Transport Labels: No mandatory hazard label for small quantities used in research or development
Special Transport Precautions: Keep dry, seal tightly, prevent shipping damage, consult local transport authority for large volume movement
EU Regulations: Not listed as SVHC, not subjected to Annex XIV or XVII restrictions under REACH
US Regulations: Not on TSCA inventory of hazardous substances, no SARA or CERCLA reporting thresholds
Canada: Domestic Substances List – present in non-hazardous form
Other Local Requirements: Compliance with laboratory safety and chemical handling laws remains the operator’s duty
Safety Assessments: Updated at workplace annually, new information from published toxicology revises PPE guidelines or use restrictions
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