Material Safety Data Sheet: (R)-2-Methyl Piperazine (L)-Tartrate

Identification

Product Name: (R)-2-Methyl Piperazine (L)-Tartrate
Chemical Formula: C11H22N2O6
CAS Number: 151682-57-6
Synonyms: (R)-2-Methylpiperazine Tartrate, Tartrate salt of (R)-2-methylpiperazine
Recommended Use: Intermediate in chemical synthesis, research reagent
Manufacturer Information: Contact details of supply firm and emergency telephone number should be available onsite; this information is necessary for fast communication during incidents.

Hazard Identification

Hazard Class: Classified as irritant to eyes, skin, and respiratory tract according to GHS
Label Elements: Signal word: Warning
Hazard Statements: Causes serious eye irritation, may cause skin irritation, may cause respiratory irritation
Pictograms: Exclamation mark (irritation hazard)
Precautionary Statements: Avoid breathing dust, wash thoroughly after handling, use protective equipment

Composition / Information on Ingredients

Chemical Name: (R)-2-Methyl Piperazine (L)-Tartrate
Purity: More than 98%
Impurities: Trace solvents and minor isomeric byproducts typical for this synthesis route, not expected above 1%
Molecular Weight: 278.3 g/mol

First Aid Measures

Eye Contact: Rinse with gentle but prolonged water flow, lifting eyelid continuously, remove contact lenses if present and easy to do, seek medical advice immediately if discomfort persists
Skin Contact: Wash area with soap and plenty of water, remove contaminated clothing, medical evaluation recommended for persistent irritation
Inhalation: Move to fresh air, maintain open airway, get medical attention in case of discomfort or symptoms like coughing or dizziness
Ingestion: Rinse mouth thoroughly, do not induce vomiting, seek immediate medical advice, provide the product label or safety sheet to medical personnel

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical powder, carbon dioxide, foam, water spray (do not use high-pressure streams which may scatter powder)
Special Protective Equipment: Firefighters should wear full protective suit and self-contained breathing apparatus
Hazardous Combustion Products: Can release nitrogen oxides, carbon monoxide, carbon dioxide, oxides of nitrogen and other toxic gases
Unusual Fire and Explosion Hazards: Product may decompose when heated, releasing vapors which could be hazardous to respiratory health, may form irritating aerosols

Accidental Release Measures

Personal Precautions: Evacuate area, ventilate space, wear gloves, safety goggles, dust mask
Environmental Precautions: Prevent entry into sewage or drainage systems, contain spill to avoid environmental contamination
Clean-Up Methods: Carefully sweep or scoop up with non-sparking tools and transfer to suitable container, avoid raising dust, wash site with copious water if appropriate, dispose of residue under applicable waste management regulations

Handling and Storage

Safe Handling: Use within well-ventilated environment, wear recommended PPE, avoid direct contact with skin or eyes, do not inhale powder or fumes
Storage: Keep tightly sealed in original container, store in a cool, dry, well-ventilated location, protect from moisture and incompatible materials like acids and oxidizers, keep away from sources of ignition

Exposure Controls and Personal Protection

Engineering Controls: General laboratory ventilation, fume hood for weighing or handling powder in quantity, eyewash station and safety shower in work area
Personal Protective Equipment: Safety goggles or face shield, Nitrile or latex gloves, long-sleeve lab coat, particulate respirator if dusting can occur
Hygiene Measures: Wash hands thoroughly after handling, change out of contaminated clothing, do not eat, drink, or smoke in work area, keep product away from skin, mouth, and eyes during use

Physical and Chemical Properties

Appearance: White to off-white crystalline powder
Odor: Faint amine odor
Melting Point: Typically between 100-120°C
Boiling Point: Decomposes before boiling
Solubility: Soluble in water, moderately soluble in polar organic solvents
pH: Aqueous solution is mildly acidic
Density: Around 1.26 g/cm³
Vapor Pressure: Negligible at room temperature
Partition Coefficient (log Kow): Not established for this compound, expected to be low based on structure

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Reactivity: Not classified as highly reactive, but can react with strong oxidizers or acids
Hazardous Reactions: May release corrosive fumes upon thermal decomposition
Conditions to Avoid: High temperatures, moisture, sources of ignition, strong acids or oxidizers
Incompatible Materials: Strong oxidizing agents, strong acids, bases
Hazardous Decomposition Products: Carbon oxides, nitrogen oxides, small organic molecules

Toxicological Information

Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Effects: Eye and skin irritant; inhalation can cause respiratory tract discomfort, coughing, headache; ingestion may lead to gastric distress, nausea, vomiting
Chronic Effects: Limited data, based on structural class repeated exposure could cause dermatitis or respiratory sensitization in sensitive individuals
Toxicity Data: No comprehensive animal LD50/LC50 values published as of yet, structure suggests moderate acute toxicity relative to alkylated piperazine salts
Other Health Information: No known carcinogenicity, mutagenicity, or reproductive toxicity based on available published toxicology for closely related analogues

Ecological Information

Ecotoxicity: Not widely studied, but similar compounds may have moderate acute aquatic toxicity, avoid uncontrolled release
Persistence and Degradability: Expected to be biodegradable based on structure of piperazine and tartrate core
Bioaccumulation Potential: Not expected to bioaccumulate appreciably due to hydrophilic properties
Mobility in Soil: Predicted to be mobile in moist environments, due to water solubility
Other Adverse Effects: No known significant ozone depletion, global warming, or photochemical ozone creation potentials

Disposal Considerations

Waste Treatment Methods: Collect and contain in a sealed container, label clearly as hazardous chemical waste
Disposal Methods: Dispose via licensed hazardous waste contractor, compliant with local, state, and national regulations
Incineration: Permitted in chemical incinerator equipped with afterburner and scrubber
Contaminated Packaging: Dispose like the product itself, empty container should not be reused unless adequately decontaminated

Transport Information

UN Number: Not assigned for small quantities
Proper Shipping Name: Chemically, not classified as Dangerous Goods in most jurisdictions for road, rail, sea, air
Transport Hazard Class: Not regulated as hazardous cargo, but best practices recommend protecting packaging from moisture, heat, rough handling
Packing Group: Not applicable
Marine Pollutant: Not designated as marine pollutant

Regulatory Information

OSHA Status: Not specifically listed; general chemical safety standards apply
TSCA Status: May be subject to reporting under TSCA Inventory
EU Classification: Not specifically listed under current ECHA regulations but should be handled as hazardous according to GHS
SARA Title III: Not classified as extremely hazardous substance
California Prop 65: No ingredients known to be listed
Other National and Local Regulations: Employer inspections and chemical inventories required, timely worker training and hazard communication practice needed, maintain and update information regularly to ensure safe use