Product Name: (R)-1-Chloro-2-propanol
Chemical Formula: C3H7ClO
Synonyms: (R)-1-Chloro-2-hydroxypropane, (R)-2-Hydroxy-1-chloropropane
CAS Number: 2931-67-9
Recommended Use: Organic synthesis, pharmaceutical intermediate, chemical research
Manufacturer: Supplier contact details required for transport and emergencies
Emergency Phone Number: Accessible numbers must be provided by the supplier/distributor
Address: Business address from labeling on container
Hazard Classification: Flammable liquid, Acute Toxicity Oral Category 4, Skin and Eye Irritant, Specific Target Organ Toxicity (Single Exposure) Category 3
Signal Word: Warning
Hazard Statements: Causes skin and serious eye irritation, may be harmful by inhalation, ingestion, or skin absorption, may cause respiratory irritation, flammable liquid and vapor
Pictogram: Exclamation mark, flame
Precautionary Statements: Keep away from open flame or sources of ignition, use only with adequate ventilation, avoid contact with skin, eyes, and clothing, wash hands thoroughly after handling, wear protective gloves and eye protection
Substance: (R)-1-Chloro-2-propanol
Chemical Identity: C3H7ClO
Purity: Greater than 98%
Impurities: Water and trace by-products from synthesis may appear in minimal amounts but remain unspecified
Inhalation: Remove person to fresh air promptly, support breathing with oxygen if necessary, seek medical advice if respiratory symptoms appear
Skin Contact: Remove any contaminated clothing, wash skin thoroughly using soap and plenty of water for several minutes, call a physician for irritation or allergic reaction
Eye Contact: Immediately flush the eyes with plenty of water for at least 15 minutes, lift eyelids to ensure complete rinsing, seek medical attention regardless of symptom severity
Ingestion: Rinse mouth thoroughly with water, never give liquids to an unconscious person, do not induce vomiting, contact poison control center or physician right away
Suitable Extinguishing Media: Use water spray, dry chemical, foam, or carbon dioxide extinguishers
Specific Hazards: Vapors form explosive mixtures with air, combustion products may release hydrochloric acid and carbon oxides
Protective Equipment: Firefighters require self-contained breathing apparatus and full protective gear
Advice for Firefighters: Keep upwind, use caution in confined spaces, prevent run-off to drains and surface waters
Personal Precautions: Evacuate non-essential personnel, wear recommended personal protective equipment including gloves, chemical goggles, and respirators where needed
Environmental Precautions: Prevent further leakage or spillage if safe to do so, avoid product release into soil, drains, and surface waters
Methods for Clean-up: Contain spillage with inert absorbent materials (sand, earth, vermiculite), collect into containers for disposal, wash spill area with copious amounts of water, ventilate the workspace
Safe Handling: Work in well-ventilated areas, avoid inhaling vapor or mist, keep away from open flames, smoking, or sources of static discharge, do not eat, drink, or smoke while handling this substance
Storage Conditions: Store in tightly closed containers in a cool, dry, well-ventilated area, segregate from oxidizers and acids, always keep product label on container, store away from food, beverages, and incompatible chemicals
Exposure Limits: No established national exposure limits, control to lowest achievable level
Engineering Controls: Utilize fume hoods or local exhaust as primary means of ventilation, use closed handling systems where possible
Personal Protective Equipment: Chemical-resistant gloves (nitrile or neoprene recommended), safety goggles or face shield, lab coat or impermeable apron, appropriate respiratory protection for higher concentrations or poor ventilation
Appearance: Colorless to pale yellow liquid
Odor: Strong, chemical odor
pH: Not applicable in pure form
Melting Point: -51°C
Boiling Point: 123–127°C
Flash Point: Around 48°C (closed cup)
Evaporation Rate: Not specified
Flammability: Flammable liquid
Upper/Lower Explosion Limits: Not specified
Vapor Pressure: Moderate at room temperature
Density: Approximately 1.15 g/cm³ at 20°C
Solubility: Soluble in water and common organic solvents
Partition Coefficient n-octanol/water (log Kow): Not available
Viscosity: Not available
Chemical Stability: Stable under standard conditions if stored properly
Reactivity: Reacts with strong acids and strong oxidizing agents, can hydrolyze slowly in water
Conditions to Avoid: Heat, flames, sparks, direct sunlight, moisture
Hazardous Decomposition Products: Upon decomposition may form toxic gases such as hydrogen chloride, carbon monoxide, and carbon dioxide
Polymerization: No hazardous polymerization expected under normal usage
Acute Toxicity: Oral rat LD50 is estimated between 180 and 300 mg/kg, based on analogs; can cause nausea, headache, dizziness, and respiratory irritation
Skin and Eye Effects: May cause burns, severe irritation, redness, blurred vision upon direct contact
Sensitization: Prolonged or repeated exposure might trigger skin sensitization in some individuals
Chronic Effects: Repeated exposure could damage kidneys, liver, and central nervous system
Mutagenicity/Carcinogenicity: No definitive data, but structurally similar chlorinated alcohols may present some concerns for genotoxicity, warrants careful use
Other Effects: Absorption through skin possible, especially in liquid form
Ecotoxicity: Toxic to aquatic organisms, possible long-term adverse effects in the aquatic environment
Persistence and Degradability: May undergo slow biodegradation in soil and water, but presence of chlorine atom implies persistence
Bioaccumulative Potential: Likely to exhibit low to moderate bioaccumulation
Mobility in Soil: Liquid at room temperature, moderately soluble in water, likely to migrate through soil easily
Other Adverse Effects: Avoid product release to the environment to minimize risk to aquatic ecosystems and drinking water sources
Waste Treatment Methods: Collect and place material in sealed, labeled hazardous waste containers
Disposal Recommendations: Dispose of contents and containers through licensed chemical disposal contractors following region-specific hazardous waste regulations
Contaminated Packaging: Empty containers should be triple rinsed; discard packaging through approved waste handlers
Prohibited Disposal: Never allow entry into drains, surface waters, or unprotected landfills
UN Number: UN1992
Proper Shipping Name: Flammable liquid, toxic, n.o.s. ((R)-1-Chloro-2-propanol mixture)
Transport Hazard Class: 3 (flammable liquids), 6.1 (toxic substances)
Packing Group: II
Label Requirements: Toxic, Flammable Liquid
Environmental Hazards: Product classified as marine pollutant for bulk shipments
Special Precautions: Handle with care to prevent leaks, spills, and exposure during transit, avoid shipping with incompatible materials
International Inventories: Listed under major chemical inventories such as TSCA (US), REACH (EU), DSL (Canada), AICS (Australia), subject to applicable quantity restrictions
Specific Regulations: Subject to local, regional, national restrictions for import, use, and disposal. May trigger workplace safety reporting and environmental monitoring
Workplace Labeling: Product labeling under OSHA Hazard Communication Standard and Globally Harmonized System (GHS) required
Other Information: Consult national regulations for information about storage, handling restrictions, and employee notification obligations
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