Product Name: (R)-1-(3-Chlorophenyl)-1,3-propanediol
Chemical Formula: C9H11ClO2
Synonyms: (R)-3-Chlorophenylpropanediol, (R)-1,3-Dihydroxy-3-chlorophenylpropane
CAS Number: 123456-78-9
Recommended Use: Research chemical, chemical synthesis intermediate
Manufacturer's Information: Technical Services, Sample Chemical Industry International, 100 Science Road, Princeton, NJ 08540
Emergency Telephone: +1-800-555-1212 (24-hour)
GHS Classification: Acute Toxicity (Oral) Category 4, Eye Irritation Category 2A, Skin Sensitizer Category 1
Pictograms: Exclamation Mark, Health Hazard
Signal Word: Warning
Hazard Statements: Harmful if swallowed; causes eye irritation; may cause an allergic skin reaction
Precautionary Statements: Avoid breathing dust or vapors; wash hands thoroughly after handling; wear protective gloves and eye protection; IF ON SKIN: Wash with plenty of water; IF IN EYES: Rinse cautiously with water for several minutes; remove contact lenses if present and easy to do; continue rinsing.
Other Hazards: At elevated temperature, vapors may cause respiratory tract irritation.
Chemical Name: (R)-1-(3-Chlorophenyl)-1,3-propanediol
CAS Number: 123456-78-9
Concentration: 98-100%
Impurities and Stabilizing Additives: Residual solvents <1%, no stabilizers reported
Other Components: No hazardous components or additives known at concentrations above relevant thresholds
Inhalation: Remove person to fresh air; keep comfortable for breathing; seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing; wash skin with plenty of soap and water; if skin irritation or rash develops, get medical attention
Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses if easy to do; continue rinsing; seek medical attention if irritation persists
Ingestion: Rinse mouth; do not induce vomiting; drink water if conscious; seek immediate medical attention
Most Important Symptoms: May cause redness, pain, burning sensation in eyes or on skin; prolonged exposure could result in dermatitis or respiratory irritation
Special Advice for First Responders: Use gloves and eye protection when giving first aid
Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical, carbon dioxide
Specific Hazards Arising from Chemical: Releases toxic fumes of hydrogen chloride and carbon oxides on decomposition, may produce dense smoke
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective clothing
Special Procedures: Evacuate area; cool exposed containers with water spray to prevent bursting
Personal Precautions: Avoid breathing dust; ventilate area; wear gloves, protective eyewear, and dust mask
Methods for Clean-Up: Use inert material (sand, earth) to contain and collect spill—sweep up carefully and dispose of following local regulations
Environmental Precautions: Prevent entry into sewers, waterways, and soil
Decontamination: Clean contaminated area thoroughly with soap solution; hold residues for proper waste disposal
Precautions for Safe Handling: Handle in a fume hood; avoid skin and eye contact; use spark-proof tools; keep containers tightly closed; practice good industrial hygiene
Storage Conditions: Store in original airtight container in a cool, dry, well-ventilated location; keep away from strong oxidants, acids, food and drink
Incompatibles: Strong oxidizers, strong acids, bases
Other Handling Advice: Do not reuse contaminated containers
Control Parameters: No occupational exposure limit established; minimize exposure by engineering controls
Engineering Controls: Use local exhaust ventilation; safety shower and eyewash station recommended
Personal Protective Equipment: Nitrile gloves, chemical safety goggles, lab coat, NIOSH-approved respirator when airborne dust is present
Hygiene Measures: Wash hands before breaks, after handling, and before eating or drinking
Appearance: White to off-white crystalline powder
Odor: Slightly phenolic
Melting Point: 102–105°C
Boiling Point: Decomposes before boiling
Vapor Pressure: Not determined
Solubility: Soluble in ethanol, slightly soluble in water
Density: 1.28 g/cm³ (estimated)
pH (aqueous soln, 1%): 5.5–6.5
Partition Coefficient (log Pow): Estimated 1.7
Flash Point: >110°C (closed cup)
Auto-ignition Temperature: Not available
Evaporation Rate: Not applicable
Viscosity: Not applicable
Chemical Stability: Stable at room temperature under recommended storage
Possibility of Hazardous Reactions: May react violently with strong oxidizers
Conditions to Avoid: Excess heat, open flames, ignition sources, exposure to moisture
Incompatible Materials: Strong acids, bases, oxidizing agents
Hazardous Decomposition Products: Hydrogen chloride, carbon monoxide, carbon dioxide, phosgene at elevated temperatures
Likely routes of exposure: Inhalation, skin and eye contact, ingestion
Acute Toxicity: Estimated LD50 oral (rat) 350 mg/kg
Irritation: Causes moderate skin and eye irritation
Sensitization: May cause allergic skin reaction in sensitive individuals
Chronic Effects: Prolonged or repeated exposure may aggravate pre-existing skin or respiratory conditions
Carcinogenicity: Not classified as carcinogen by IARC, NTP, or OSHA
Mutagenicity: No data available
Reproductive Toxicity: No evidence of risk in available animal data
Target Organs: Skin, eyes, respiratory tract
Toxicity: Harmful to aquatic organisms, may cause long-term effects in the aquatic environment
Persistence and Degradability: Not readily biodegradable; possible accumulation in sediment
Bioaccumulative Potential: Moderate potential (estimated log Kow 1.7)
Mobility in Soil: Low to moderate, depending on soil characteristics
Other Adverse Effects: Avoid release to the environment, possible risk to drinking water sources
Disposal Methods: Dispose through licensed chemical waste contractor in accordance with federal, state, and local regulations
Contaminated Packaging: Triple rinse then offer for recycling or dispose as hazardous waste
Special Precautions: Do not allow into drains, sewers, or waterways
Regulatory Provisions: Hand over to authorized waste disposal facility only
UN Number: 3276 (Hazardous material)
UN Proper Shipping Name: Toxic solid, organic, n.o.s. ((R)-1-(3-Chlorophenyl)-1,3-propanediol)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Special Precautions: Ensure no spillage during loading/unloading; protect from heat and moisture
Environmental Hazards: Marine pollutant
Transport in Bulk: Not recommended by bulk under MARPOL/IBC code
US Federal Regulations: Listed on TSCA inventory; subject to SARA Title III Section 313 (emissions reporting); not regulated under CERCLA or RCRA
EU Regulations: Substances of Very High Concern (SVHC) criteria do not apply; classified per REACH Article 33 as hazardous for health
Canada (DSL/NDSL): Present on NDSL
Other International Inventories: Registered in Japan ENCS and Korea ECL
Labeling Requirements: GHS pictograms and hazard statements required on container label
Restrictions: Use for laboratory or industrial purposes only; not for pharmaceutical, houseware, or food use
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