Product Name: (R)-(-)-1,2-Propanediol
Synonyms: (R)-Propylene glycol, (R)-1,2-Dihydroxypropane
Chemical Formula: C3H8O2
CAS Number: 4254-15-3
Recommended Use: Laboratory reagent, chemical synthesis, solvent
Manufacturer: Refer to supplier information on packaging
Contact Information: Refer to supplier for emergency contact numbers
GHS Classification: Not considered hazardous under normal handling and use; may cause mild irritation to eyes or skin
Hazard Symbols: None assigned
Signal Word: None
Routes of Exposure: Inhalation, skin and eye contact, ingestion
Potential Health Effects: Inhalation of vapors may cause mild respiratory discomfort, eye or skin contact may cause temporary irritation, ingestion can have gastrointestinal effects such as nausea
Environmental Hazards: Low hazard for aquatic or terrestrial life
Chemical Name: (R)-(-)-1,2-Propanediol
Concentration: >98% by weight
Impurities: Not significant at standard purity levels
Molecular Weight: 76.09 g/mol
General Information: Move affected individual to fresh air, remove contaminated clothing
Inhalation: Move to fresh air, consult a doctor if discomfort continues
Skin Contact: Rinse skin with water and soap for several minutes, seek medical attention if symptoms worsen
Eye Contact: Rinse cautiously with ample water for at least 15 minutes, remove lenses if present and easy to do, get medical advice if irritation persists
Ingestion: Rinse mouth, give water to dilute, consult a physician if symptoms develop
Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, alcohol-resistant foam, water spray
Unsuitable Extinguishing Media: Strong water jet can cause spatter and spread
Specific Hazards: Combustible liquid, can emit carbon monoxide and carbon dioxide in flame
Protective Equipment for Firefighters: Standard protective gear and self-contained breathing apparatus
Special Information: Prevent runoff from entering watercourses or drains
Personal Precautions: Wear gloves, safety goggles, and protective lab clothing
Environmental Precautions: Prevent further leakage or spillage into drains, soil or waterways
Material Containment and Cleanup: Soak up spill with inert absorbent (sand, earth), collect residue in clearly labeled containers for proper disposal, ventilate area
Cleaning Method: Wash spill site after material pick-up
Precautions for Safe Handling: Handle in well-ventilated spaces, avoid breathing vapors, prevent skin and eye contact, implement basic chemical hygiene
Storage Conditions: Store tightly sealed in a dry, well-ventilated, cool area, away from ignition sources and strong oxidizers
Incompatibilities: Strong oxidizers, strong acids
Specific Storage Requirements: Keep container upright, avoid excessive heat and light
Exposure Limits: No occupational exposure limit set for (R)-(-)-1,2-Propanediol
Engineering Controls: Use local exhaust or adequate general ventilation
Personal Protective Equipment: Gloves (nitrile or latex), splash goggles, lab coat
Hygiene Measures: Wash hands thoroughly after use, avoid eating, drinking, or smoking during use
Appearance: Colorless, viscous liquid
Odor: Practically odorless
Melting Point: -59 °C
Boiling Point: 188 °C
Flash Point: 99 °C (Open cup)
Solubility: Miscible with water, ethanol, acetone
Density: 1.036 g/cm³ at 20°C
pH: Neutral
Vapor Pressure: Very low at room temperature
Viscosity: High
Chemical Stability: Stable under normal conditions, shelf-stable in sealed container
Reactivity: Not particularly reactive, can form peroxides under certain conditions
Conditions to Avoid: Excessive heat, open flame, contact with strong oxidizing agents
Hazardous Decomposition: Thermal decomposition can yield carbon oxides
Acute Toxicity: Oral LD50 in rats: 20,000 mg/kg (low toxicity)
Skin Irritation: Mild and reversible, no evidence of sensitization
Eye Irritation: Mild, temporary irritation possible
Inhalation: At normal use, little risk, very high vapor may cause transient respiratory irritation
Chronic Toxicity: Low risk, not classified as carcinogenic, mutagenic, or teratogenic under typical exposure
Other Effects: No evidence of sensitization or reproductive toxicity
Persistence and Degradability: Readily biodegradable under environmental conditions
Bioaccumulative Potential: Low, not likely to bioaccumulate in aquatic organisms
Aquatic Toxicity: LC50 (96h, fish): >1000 mg/L (very low toxicity)
Soil Mobility: High solubility suggests moderate mobility in ground environments
Other Adverse Effects: Not likely to cause significant effects on the environment in typical small spill contexts
Waste Disposal Method: Dispose as non-hazardous organic waste in accordance with local, national, international regulations
Container Disposal: Wash and reuse or dispose in compliance with legal requirements
Special Precautions: Do not discharge into drains or natural water bodies in raw, concentrated form
UN Number: Not regulated
Proper Shipping Name: Not dangerous for transport
Transport Hazard Class: Not assigned
Packing Group: Not regulated
Labeling Requirements: Not necessary for routine ground or air shipment
Special Transport Notes: Secure containers, prevent leaks, avoid extreme temperatures
Inventory Listings: Registered under chemical inventories (TSCA, EINECS, DSL, etc.)
OSHA Hazards: Not classified as hazardous or controlled
EU Classification: Not dangerous according to EU directives
Other Requirements: All handling and storage must follow local occupational safety and chemical storage regulations
Labeling: Accurate chemical information, clear manufacturer data, clear hazard/precautionary statements where applicable
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